Determination of antiviral nucleoside analogues AM365 and AM188 in perfusate and bile of the isolated perfused rat liver using HPLC

Biomedical Chromatography

Volumn 20, Issue 3, 2006, Pages 244-250

  Wang, Jiping ^a,b   Nation, Roger L ^b   Evans, Allan M ^a   Cox, Susan ^c   Li, Jian ^b  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c Avexa Ltd   (Australia)

Author keywords

AM188; AM365; HPLC; Isolated perfused rat liver; Nucleoside analogue

Indexed keywords

BIOMOLECULES; BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; SODIUM COMPOUNDS;

AM188; AM365; ANALYTICAL COLUMNS; ANTIVIRAL NUCLEOSIDE; HPLC; ISOLATED PERFUSED RAT LIVER; MOBILE PHASIS; NUCLEOSIDE ANALOGS; RAT LIVERS; SODIUM ORTHOPHOSPHATE;

RATS;

2 AMINO 9 (3 HYDROXY 2 HYDROXYMETHYLPROP 1 YL)PURINE; 9 (3 HYDROXY 2 HYDROXYMETHYLPROP 1 YL)GUANINE; AM 188; AM 365; ANTIVIRUS AGENT; METHANOL; NUCLEOSIDE ANALOG; ORGANOPHOSPHATE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL TISSUE; ARTICLE; BILE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DISPOSITION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER METABOLISM; LIVER PERFUSION; NONHUMAN; PH; QUALITY CONTROL; QUANTITATIVE ANALYSIS; RAT; VALIDATION PROCESS;

ANIMALIA;

EID: 33645366185     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.554     Document Type: Article

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