메뉴 건너뛰기




Volumn 41, Issue 2, 2006, Pages 160-167

HIV-1 reverse transcriptase gene 103K/N and 184M/V combinations in tandem: Detection and quantification of HIV-1 populations in the CD45RO+ T-cell compartment by a double-ARMS real-time PCR assay

Author keywords

103K N; 184M V; CD45RO+ T cell compartment; HIV drug resistance resistance mutations; Mutations in tandem

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; CD45RO ANTIGEN; EFAVIRENZ; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE; SAQUINAVIR; TENOFOVIR; ZIDOVUDINE; CD45 ANTIGEN; OXAZINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 33645320316     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.qai.0000191998.70034.64     Document Type: Article
Times cited : (4)

References (42)
  • 1
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • Wei X, Ghosh SK, Taylor ME, et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature. 1995;373:117-122.
    • (1995) Nature , vol.373 , pp. 117-122
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3
  • 2
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
    • Ho DD, Neumann AU, Perelson AS, et al. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature. 1995;373:123-126.
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1    Neumann, A.U.2    Perelson, A.S.3
  • 3
    • 0024273119 scopus 로고
    • The accuracy of reverse transcriptase from HIV-1
    • Roberts JD, Bebenek K, Kunkel TA. The accuracy of reverse transcriptase from HIV-1. Science. 1988;242:1171-1173.
    • (1988) Science , vol.242 , pp. 1171-1173
    • Roberts, J.D.1    Bebenek, K.2    Kunkel, T.A.3
  • 4
    • 0028792184 scopus 로고
    • In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency
    • Chun TW, Finzi D, Margolick J, et al. In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency. Nat Med. 1995;1:1284-1290.
    • (1995) Nat Med , vol.1 , pp. 1284-1290
    • Chun, T.W.1    Finzi, D.2    Margolick, J.3
  • 5
    • 0032953920 scopus 로고    scopus 로고
    • Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • Finzi D, Blankson J, Siliciano JD, et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med. 1999;5:512-517.
    • (1999) Nat Med , vol.5 , pp. 512-517
    • Finzi, D.1    Blankson, J.2    Siliciano, J.D.3
  • 6
    • 0038579210 scopus 로고    scopus 로고
    • Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
    • Siliciano JD, Kajdas J, Finzi D, et al. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med. 2003;9:727-728.
    • (2003) Nat Med , vol.9 , pp. 727-728
    • Siliciano, J.D.1    Kajdas, J.2    Finzi, D.3
  • 7
    • 0037302334 scopus 로고    scopus 로고
    • Latency in human immunodeficiency virus type 1 infection: No easy answers
    • Persaud D, Zhou Y, Siliciano JM, et al. Latency in human immunodeficiency virus type 1 infection: no easy answers. J Virol. 2003;77:1659-1665.
    • (2003) J Virol , vol.77 , pp. 1659-1665
    • Persaud, D.1    Zhou, Y.2    Siliciano, J.M.3
  • 8
    • 0036720438 scopus 로고    scopus 로고
    • Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure
    • Ruff CT, Ray SC, Kwon P, et al. Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure. J Virol. 2002;76:9481-9492.
    • (2002) J Virol , vol.76 , pp. 9481-9492
    • Ruff, C.T.1    Ray, S.C.2    Kwon, P.3
  • 9
    • 10744223424 scopus 로고    scopus 로고
    • Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions
    • Metzner KJ, Bonhoeffer S, Fischer M, et al. Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions. J Infect Dis. 2003;188:1433-1443.
    • (2003) J Infect Dis , vol.188 , pp. 1433-1443
    • Metzner, K.J.1    Bonhoeffer, S.2    Fischer, M.3
  • 10
    • 1842484005 scopus 로고    scopus 로고
    • Role of minority populations of human immunodeficiency virus type 1 in the evolution of viral resistance to protease inhibitors
    • Charpentier C, Dwyer DE, Mammano F, et al. Role of minority populations of human immunodeficiency virus type 1 in the evolution of viral resistance to protease inhibitors. J Virol. 2004;78:4234-4247.
    • (2004) J Virol , vol.78 , pp. 4234-4247
    • Charpentier, C.1    Dwyer, D.E.2    Mammano, F.3
  • 11
    • 0036149707 scopus 로고    scopus 로고
    • Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection
    • Brenner BG, Routy JP, Petrella M, et al. Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection. J Virol. 2002;76:1753-1761.
    • (2002) J Virol , vol.76 , pp. 1753-1761
    • Brenner, B.G.1    Routy, J.P.2    Petrella, M.3
  • 12
    • 4143113433 scopus 로고    scopus 로고
    • Persistence of primary drug resistance among recently HIV-1 infected adults
    • Barbour JD, Hecht FM, Wrin T, et al. Persistence of primary drug resistance among recently HIV-1 infected adults. AIDS. 2004;18:1683-1689.
    • (2004) AIDS , vol.18 , pp. 1683-1689
    • Barbour, J.D.1    Hecht, F.M.2    Wrin, T.3
  • 13
    • 2942618578 scopus 로고    scopus 로고
    • The lymphocyte HIV reservoir in patients on long-term HAART is a memory of virus evolution
    • Lambotte O, Chaix ML, Gubler B, et al. The lymphocyte HIV reservoir in patients on long-term HAART is a memory of virus evolution. AIDS. 2004;18:1147-1158.
    • (2004) AIDS , vol.18 , pp. 1147-1158
    • Lambotte, O.1    Chaix, M.L.2    Gubler, B.3
  • 14
    • 0026077832 scopus 로고
    • Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors
    • Nunberg JH, Schleif WA, Boots EJ, et al. Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors. J Virol. 1991;65:4887-4892.
    • (1991) J Virol , vol.65 , pp. 4887-4892
    • Nunberg, J.H.1    Schleif, W.A.2    Boots, E.J.3
  • 15
    • 0028841320 scopus 로고
    • Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (- -)-2′,3′-dideoxy-3′-thiacytidine
    • Kavlick MF, Shirasaka T, Kojima E, et al. Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (- -)-2′,3′-dideoxy-3′-thiacytidine. Antiviral Res. 1995;28:133-146.
    • (1995) Antiviral Res , vol.28 , pp. 133-146
    • Kavlick, M.F.1    Shirasaka, T.2    Kojima, E.3
  • 16
    • 0027285372 scopus 로고
    • Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
    • Tisdale M, Kemp SD, Parry NR, et al. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc Natl Acad Sci USA. 1993;90:5653-5656.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5653-5656
    • Tisdale, M.1    Kemp, S.D.2    Parry, N.R.3
  • 17
    • 0033081564 scopus 로고    scopus 로고
    • Resistance to non-nucleoside inhibitors of HIV-1 reverse transcriptase
    • Bacheler LT. Resistance to non-nucleoside inhibitors of HIV-1 reverse transcriptase. Drug Resist Updat. 1999;2:56-67.
    • (1999) Drug Resist Updat , vol.2 , pp. 56-67
    • Bacheler, L.T.1
  • 18
    • 0035292858 scopus 로고    scopus 로고
    • International perspectives on antiretroviral resistance: Non-nucleoside reverse transcriptase inhibitor resistance
    • Deeks SG. International perspectives on antiretroviral resistance: non-nucleoside reverse transcriptase inhibitor resistance. J Acquir Immune Defic Syndr. 2001;26(Suppl 1):S25-S33.
    • (2001) J Acquir Immune Defic Syndr , vol.26 , Issue.1 SUPPL.
    • Deeks, S.G.1
  • 19
    • 0345486993 scopus 로고    scopus 로고
    • Patterns of resistance and cross-resistance to human immunodeficiency virus type 1 reverse transcriptase inhibitors in patients treated with the nonnucleoside reverse transcriptase inhibitor loviride
    • Miller V, de Bethune MP, Kober A, et al. Patterns of resistance and cross-resistance to human immunodeficiency virus type 1 reverse transcriptase inhibitors in patients treated with the nonnucleoside reverse transcriptase inhibitor loviride. Antimicrob Agents Chemother. 1998;42:3123-3129.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3123-3129
    • Miller, V.1    De Bethune, M.P.2    Kober, A.3
  • 20
    • 0034639473 scopus 로고    scopus 로고
    • Mechanisms of virologie failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy
    • Trilege (Agence Nationale de Recherches sur le SIDA 072) Study Team
    • Descamps D, Flandre P, Calvez V, et al. Mechanisms of virologie failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Trilege (Agence Nationale de Recherches sur le SIDA 072) Study Team. JAMA. 2000;283:205-211.
    • (2000) JAMA , vol.283 , pp. 205-211
    • Descamps, D.1    Flandre, P.2    Calvez, V.3
  • 21
    • 2642704250 scopus 로고    scopus 로고
    • Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy
    • Gunthard HF, Wong JK, Ignacio CC, et al. Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy. J Virol. 1998;72:2422-2428.
    • (1998) J Virol , vol.72 , pp. 2422-2428
    • Gunthard, H.F.1    Wong, J.K.2    Ignacio, C.C.3
  • 22
    • 0036265127 scopus 로고    scopus 로고
    • The impact of the M184V substitution in HIV-1 reverse transcriptase on treatment response
    • Miller V, Stark T, Loeliger AE, et al. The impact of the M184V substitution in HIV-1 reverse transcriptase on treatment response. HIV Med. 2002;3:135-145.
    • (2002) HIV Med , vol.3 , pp. 135-145
    • Miller, V.1    Stark, T.2    Loeliger, A.E.3
  • 23
    • 0032875344 scopus 로고    scopus 로고
    • Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: A comparative analysis of RT variants Leu74Val and lamivudrne-selected Met184Val
    • Sharma PL, Crumpacker CS. Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudrne-selected Met184Val. J Virol. 1999;73: 8448-8456.
    • (1999) J Virol , vol.73 , pp. 8448-8456
    • Sharma, P.L.1    Crumpacker, C.S.2
  • 24
    • 0027957791 scopus 로고
    • Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy
    • Richman DD, Havlir D, Corbeil J, et al. Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy. J Virol. 1994;68:1660-1666.
    • (1994) J Virol , vol.68 , pp. 1660-1666
    • Richman, D.D.1    Havlir, D.2    Corbeil, J.3
  • 25
    • 2942565660 scopus 로고    scopus 로고
    • Structural and biochemical effects of human immunodeficiency virus mutants resistant to non-nucleoside reverse transcriptase inhibitors
    • Domaoal RA, Demeter LM. Structural and biochemical effects of human immunodeficiency virus mutants resistant to non-nucleoside reverse transcriptase inhibitors. Int J Biochem Cell Biol. 2004;36:1735-1751.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 1735-1751
    • Domaoal, R.A.1    Demeter, L.M.2
  • 26
    • 0032190074 scopus 로고    scopus 로고
    • Diagnosis of familial Mediterranean fever by a molecular genetics method
    • Eisenberg S, Aksentijevich I, Deng Z, et al. Diagnosis of familial Mediterranean fever by a molecular genetics method. Ann Intern Med. 1998;129:539-542.
    • (1998) Ann Intern Med , vol.129 , pp. 539-542
    • Eisenberg, S.1    Aksentijevich, I.2    Deng, Z.3
  • 27
    • 0024605518 scopus 로고
    • Analysis of any point mutation in DNA: The amplification refractory mutation system (ARMS)
    • Newton CR, Graham A, Heptinstall LE, et al. Analysis of any point mutation in DNA: the amplification refractory mutation system (ARMS). Nucleic Acids Res. 1989;17:2503-2516.
    • (1989) Nucleic Acids Res , vol.17 , pp. 2503-2516
    • Newton, C.R.1    Graham, A.2    Heptinstall, L.E.3
  • 28
    • 0025869153 scopus 로고
    • Analysis of apolipoprotein e genotypes by the Amplification Refractory Mutation System
    • Wenham PR, Newton CR, Price WH. Analysis of apolipoprotein E genotypes by the Amplification Refractory Mutation System. Clin Chem. 1991;37:241-244.
    • (1991) Clin Chem , vol.37 , pp. 241-244
    • Wenham, P.R.1    Newton, C.R.2    Price, W.H.3
  • 29
    • 0025744797 scopus 로고
    • Direct haplotype determination by double ARMS: Specificity, sensitivity and genetic applications
    • Lo YM, Patel P, Newton CR, et al. Direct haplotype determination by double ARMS: specificity, sensitivity and genetic applications. Nucleic Acids Res. 1991;19:3561-3567.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3561-3567
    • Lo, Y.M.1    Patel, P.2    Newton, C.R.3
  • 30
    • 27744581514 scopus 로고    scopus 로고
    • + T cells of patients on HAART with a viremia less than 1000 copies/ml
    • in press
    • + T cells of patients on HAART with a viremia less than 1000 copies/ml. J Clin Virol. 2005 (in press).
    • (2005) J Clin Virol
    • Mohey, R.1    Jørgensen, L.B.2    Møller, B.K.3
  • 31
    • 0034987622 scopus 로고    scopus 로고
    • Changes in human immunodeficiency virus type 1 populations after treatment interruption in patients failing antiretroviral therapy
    • Hance AJ, Lemiale V, Izopet J, et al. Changes in human immunodeficiency virus type 1 populations after treatment interruption in patients failing antiretroviral therapy. J Virol. 2001;75:6410-6417.
    • (2001) J Virol , vol.75 , pp. 6410-6417
    • Hance, A.J.1    Lemiale, V.2    Izopet, J.3
  • 32
    • 19944428265 scopus 로고    scopus 로고
    • Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis
    • Palmer S, Kearney M, Maldarelli F, et al. Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis. J Clin Microbiol. 2005;43:406-413.
    • (2005) J Clin Microbiol , vol.43 , pp. 406-413
    • Palmer, S.1    Kearney, M.2    Maldarelli, F.3
  • 33
    • 3042817611 scopus 로고    scopus 로고
    • Persistence of multidrug-resistant HIV-1 without antiretroviral treatment 2 years after sexual transmission
    • Delaugerre C, Morand-Joubert L, Chaix ML, et al. Persistence of multidrug-resistant HIV-1 without antiretroviral treatment 2 years after sexual transmission. Antivir Ther. 2004;9:415-421.
    • (2004) Antivir Ther , vol.9 , pp. 415-421
    • Delaugerre, C.1    Morand-Joubert, L.2    Chaix, M.L.3
  • 34
    • 1642277960 scopus 로고    scopus 로고
    • Detection of drug-resistant minority variants of HIV-1 during virologie failure of indinavir, lamivudine, and zidovudine
    • Dykes C, Najjar J, Bosch RJ, et al. Detection of drug-resistant minority variants of HIV-1 during virologie failure of indinavir, lamivudine, and zidovudine. J Infect Dis. 2004;189:1091-1096.
    • (2004) J Infect Dis , vol.189 , pp. 1091-1096
    • Dykes, C.1    Najjar, J.2    Bosch, R.J.3
  • 35
    • 2442710266 scopus 로고    scopus 로고
    • Novel recombinant phenotypic assay for clonal analysis of reverse transcriptase mutations conferring drug resistance to HIV-1 variants
    • Paolucci S, Baldanti F, Zavattoni M, et al. Novel recombinant phenotypic assay for clonal analysis of reverse transcriptase mutations conferring drug resistance to HIV-1 variants. J Antimicrob Chemother. 2004;53:766-771.
    • (2004) J Antimicrob Chemother , vol.53 , pp. 766-771
    • Paolucci, S.1    Baldanti, F.2    Zavattoni, M.3
  • 36
    • 13844274980 scopus 로고    scopus 로고
    • Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART
    • Nettles RE, Kieffer TL, Kwon P, et al. Intermittent HIV-1 viremia (Blips) and drug resistance in patients receiving HAART. JAMA. 2005;293:817-829.
    • (2005) JAMA , vol.293 , pp. 817-829
    • Nettles, R.E.1    Kieffer, T.L.2    Kwon, P.3
  • 37
    • 0027373308 scopus 로고
    • High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase
    • Boucher CA, Cammack N, Schipper P, et al. High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother. 1993;37:2231-2234.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2231-2234
    • Boucher, C.A.1    Cammack, N.2    Schipper, P.3
  • 38
    • 0029028067 scopus 로고
    • Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
    • Larder BA, Kemp SD, Harrigan PR. Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Science. 1995;269:696-699.
    • (1995) Science , vol.269 , pp. 696-699
    • Larder, B.A.1    Kemp, S.D.2    Harrigan, P.R.3
  • 39
    • 20644436472 scopus 로고    scopus 로고
    • In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA
    • Wainberg MA, Miller MD, Quan Y, et al. In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA. Antivir Ther. 1999;4:87-94.
    • (1999) Antivir Ther , vol.4 , pp. 87-94
    • Wainberg, M.A.1    Miller, M.D.2    Quan, Y.3
  • 40
    • 0032501984 scopus 로고    scopus 로고
    • Lamivudine resistance of HIV type 1 does not delay development of resistance to nonnucleoside HIV type 1-specific reverse transcriptase inhibitors as compared with wild-type HIV type 1
    • Jonckheere H, Witvrouw M, De CE, et al. Lamivudine resistance of HIV type 1 does not delay development of resistance to nonnucleoside HIV type 1-specific reverse transcriptase inhibitors as compared with wild-type HIV type 1. AIDS Res Hum Retroviruses. 1998;14:249-253.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 249-253
    • Jonckheere, H.1    Witvrouw, M.2    De, C.E.3
  • 41
    • 0037974512 scopus 로고    scopus 로고
    • The M184V substitution in human immunodeficiency virus type 1 reverse transcriptase delays the development of resistance to amprenavir and efavirenz in subtype B and C clinical isolates
    • Diallo K, Brenner B, Oliveira M, et al. The M184V substitution in human immunodeficiency virus type 1 reverse transcriptase delays the development of resistance to amprenavir and efavirenz in subtype B and C clinical isolates. Antimicrob Agents Chemother. 2003;47:2376-2379.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2376-2379
    • Diallo, K.1    Brenner, B.2    Oliveira, M.3
  • 42
    • 4143088125 scopus 로고    scopus 로고
    • Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance
    • Ross L, Parkin N, Chappey C, et al. Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance. AIDS. 2004;18:1691-1696.
    • (2004) AIDS , vol.18 , pp. 1691-1696
    • Ross, L.1    Parkin, N.2    Chappey, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.