Smooth muscle cell: A key cell for plaque vulnerability regulation?

Circulation Research

Volumn 98, Issue 4, 2006, Pages 448-449

  Bochaton Piallat, Marie Luce ^a   Gabbiani, Giulio ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

smooth muscle actin; CITTA; Collagen; MHC II; Myofibroblast

Indexed keywords

ATHEROMA; ATHEROSCLEROTIC PLAQUE; CELL POPULATION; EDITORIAL; EXTRACELLULAR MATRIX; HUMAN; IMMUNOCOMPETENT CELL; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; ATHEROSCLEROSIS; CYTOLOGY; FIBROBLAST; GENE; GENETICS; METABOLISM; NOTE; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

COLLAGEN; GAMMA INTERFERON; MHC CLASS II TRANSACTIVATOR PROTEIN; NUCLEAR PROTEIN; TRANSACTIVATOR PROTEIN;

ATHEROSCLEROSIS; COLLAGEN; FIBROBLASTS; GENES, MHC CLASS II; HUMANS; INTERFERON TYPE II; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NUCLEAR PROTEINS; TRANS-ACTIVATORS;

EID: 33645293510     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000214330.15785.46     Document Type: Editorial

References (14)

1. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;352:1685-1695.
2. Libby P. Coronary artery injury and the biology of atherosclerosis: inflammation, thrombosis, and stabilization. Am J Cardiol. 2000;86:3J-8J; discussion 8J-9J.
3. Barnes MJ, Farndale RW. Collagens and atherosclerosis. Exp Gerontol. 1999;34:513-525.
4. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol. 2002;3:349-363.
5. Ronnov-Jessen L, Petersen OW, Koteliansky VE, Bissell MJ. The origin of the myofibroblasts in breast cancer. J Clin Invest. 1995;95:859-873.
6. Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003;112:1776-1784.
7. Hashimoto N, Jin H, Liu T, Chensue SW, Phan SH. Bone marrow-derived progenitor cells in pulmonary fibrosis. J Clin Invest. 2004;113:243-252.
8. Hao H, Gabbiani G, Camenzind E, Bacchetta M, Virmani R, Bochaton-Piallat ML. Phenotypic modulation of intima and media smooth muscle cells in fatal cases of coronary artery lesion. Arterioscler Thromb Vasc Biol. 2006;26:326-332.
9. Libby P, Sukhova G, Lee RT, Galis ZS. Cytokines regulate vascular functions related to stability of the atherosclerotic plaque. J Cardiovasc Pharmacol. 1995;25:S9-S12.
10. Xu Y, Wang L, Buttice G, Sengupta PK, Smith BD. Major histocompatibility class II transactivator (CIITA) mediates repression of collagen (COL1A2) transcription by interferon gamma (IFN-gamma). J Biol Chem. 2004;279:41319- 41332.
11. Xu Y, Wang L, Buttice G, Sengupta PK, Smith BD. Interferon gamma repression of collagen (COL1A2) transcription is mediated by the RFX5 complex. J Biol Chem. 2003;278:49134-49144.
12. Hansson GK, Hellstrand M, Rymo L, Rubbia L, Gabbiani G. Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells. J Exp Med. 1989;170:1595-1608.
13. Jonasson L, Holm J, Skalli O, Gabbiani G, Hansson GK. Expression of class II transplantation antigen on vascular smooth muscle cells in human atherosclerosis. J Clin Invest. 1985;76:125-131.
14. Butticè G, Miller J, Wang L, Smith BD. Interferon-γ induces major histocompatibility (MHC) Class II transactivator (CIITA) that mediates collagen repression and MHC II activation by human aortic smooth muscle cells. Circ Res. 2006;98:472-479.