Evaluation of analogues of DRDE-07 as prophylactic agents against the lethality and toxicity of sulfur mustard administered through percutaneous route

Journal of Applied Toxicology

Volumn 26, Issue 2, 2006, Pages 115-125

  Kulkarni, A S ^a   Vijayaraghavan, R ^a   Anshoo, Gautam ^a   Satish, H T ^a   Pathak, U ^a   Raza, S K ^a   Pant, S C ^a   Malhotra, R C ^a   Prakash, A O ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

Antidotes; DNA damage; DRDE 07; DRDE 07 analogues; GSH; Histopathology; Prophylaxis; Sulfur mustard

Indexed keywords

2 (2 AMINOETHYLAMINO)ETHYLPHENYLSULFIDE; AMIFOSTINE; ANTIDOTE; DNA FRAGMENT; DRDE 07; DRDE 09; DRDE 10; DRDE 21; DRDE 23; DRDE 30; DRDE 35; DRDE 38; GLUTATHIONE; MUSTARD GAS; SULFIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOXICITY; EXPERIMENTAL MODEL; FEMALE; HISTOPATHOLOGY; LD 50; LIPOPHILICITY; LIVER FUNCTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; RAT; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; AMIFOSTINE; ANIMALS; BODY WEIGHT; CHEMICAL WARFARE AGENTS; CHROMATOGRAPHY, THIN LAYER; FEMALE; GLUTATHIONE; LETHAL DOSE 50; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MUSTARD GAS; ORGAN SIZE; RATS; SKIN; SPLEEN;

ANIMALIA;

EID: 33645278079     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1114     Document Type: Article

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