The first palladium-catalyzed Sonogashira coupling of unactivated secondary alkyl bromides

Tetrahedron Letters

Volumn 47, Issue 17, 2006, Pages 2925-2928

  Altenhoff, Gereon ^a   Würtz, Sebastian ^b   Glorius, Frank ^b  

^a BASF SE   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Cross coupling; N heterocyclic carbene; Palladium; Secondary alkyl halide; Sonogashira coupling

Indexed keywords

1,2 DIAMINOCYCLOHEXANE; ALKYNE DERIVATIVE; BROMINE DERIVATIVE; CARBENE; CYCLOHEPTYL BROMIDE; HALIDE; LIGAND; PALLADIUM; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CROSS COUPLING REACTION; SONOGASHIRA REACTION; SUBSTITUTION REACTION;

EID: 33645243581     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.02.111     Document Type: Article

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44. 4 (20 mL) and concentrated under reduced pressure. After purification by flash chromatography (eluent: hexane or pentane/diethylether) the products were obtained as pale-yellow liquids.