Membranes affinity of 10-hydroxycamptothecin and SN-38, anticancer agents, determined by fluorescence spectra analysis

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 6158, Issue , 2006, Pages

  Cyrankiewicz, Michał ^a   Ziomkowska, Blanka ^a   Kruszewski, Stefan ^a   Siuda, Ryszard ^b  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b UNIVERSITY OF TECHNOLOGY AND LIFE SCIENCES   (Poland)

Author keywords

10 hydroxycamptothecin; Camptothecin; Fluorescence; Liposomes; SN 38

Indexed keywords

ASSOCIATION REACTIONS; CELL MEMBRANES; FLUORESCENCE; HYDROLYSIS; LIPIDS; TUMORS;

10-HYDROXYCAMPTOTHECIN; CAMPTOTHECIN; LIPOSOMES; SN-38;

DRUG PRODUCTS;

EID: 33645241000     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.675791     Document Type: Conference Paper

References (7)

1. M.E Wall, M.C. Wani, C.E. Cook, "Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata", J. Am. Chem. Soc., 88, 3888-3890, 1966.
2. L.F. Liu, S.D. Desai, T-K. Li, Mao Y., M. Sun, S-P. Sim, "Mechanism of Action of Camptothecin", Ann. N. Y. Acad. Sci., 922, 11-26, 2000.
3. Z. Mi, T.G. Burke, "Differential interactions of camptothecin lactone and carboxylate forms with human blood components", Biochemistry 33, 10325-10336, 1994.
4. T.G. Burke, A.K. Mishra, M.C. Wani, M.E. Wall, "Lipid bilayer partitioning and stability of camptothecin drugs", Biochemistry 32, 5352-5364, 1993.
5. H. Białek, "System for computer recording and analysis of fluorescence spectra using momochromator SPM-2", (in polish) diploma thesis Instytut Matematyki i Fizyki ATR Bydgoszcz, 2003.
6. S. Kruszewski, T.G. Burke, "Camptothecins affinity to HSA and membranes determined by fluorescence anisotropy measurements", Opt. Appl., 32, 721-730, 2002.
7. th Slovak-Czech-Polish Optical Conference on Wave and Quantum Aspects of Contemporary Optics, Nitra, Slovak Republic, 2004.