-
1
-
-
0033765491
-
Prognostic significance of p53 alterations in patients with non-small cell lung cancer: A meta-analysis
-
Mitsudomi T, Hamajima N, Ogawa M, Takahashi T. Prognostic significance of p53 alterations in patients with non-small cell lung cancer: a meta-analysis. Clin Cancer Res 2000;6:4055-4063.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4055-4063
-
-
Mitsudomi, T.1
Hamajima, N.2
Ogawa, M.3
Takahashi, T.4
-
2
-
-
0031908238
-
Mutation of p53 and K-ras genes as prognostic factors for non-small cell lung cancer
-
Huang C, Taki T, Adachi M, Konishi T, Higashiyama M, Kinoshita M, et al. Mutation of p53 and K-ras genes as prognostic factors for non-small cell lung cancer. Int J Oncol 1998;12:553-563.
-
(1998)
Int J Oncol
, vol.12
, pp. 553-563
-
-
Huang, C.1
Taki, T.2
Adachi, M.3
Konishi, T.4
Higashiyama, M.5
Kinoshita, M.6
-
4
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
-
5
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995;80:293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
6
-
-
0029131447
-
A functional p53-responsive intronic promoter is contained within the human mdm2 gene
-
Zauberman A, Flusberg D, Haupt Y, Barak Y, Oren M. A functional p53-responsive intronic promoter is contained within the human mdm2 gene. Nucleic Acids Res 1995;23:2584-2592.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2584-2592
-
-
Zauberman, A.1
Flusberg, D.2
Haupt, Y.3
Barak, Y.4
Oren, M.5
-
7
-
-
0037377060
-
Ubiquitination, phosphorylation and acetylation: The molecular basis for p53 regulation
-
Brooks CL, Gu W. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr Opin Cell Biol 2003;15:164-171.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 164-171
-
-
Brooks, C.L.1
Gu, W.2
-
8
-
-
0037329056
-
The p53-Mdm2 module and the ubiquitin system
-
Michael D, Oren M. The p53-Mdm2 module and the ubiquitin system. Semin Cancer Biol 2003;13:49-58.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 49-58
-
-
Michael, D.1
Oren, M.2
-
9
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
Honda R, Tanaka H, Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 1997;420:25-27.
-
(1997)
FEBS Lett
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
10
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, et al. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 2002;416:648-653.
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Qin, J.6
-
11
-
-
0030747031
-
p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung
-
Komiya T, Hosono Y, Hirashima T, Masuda N, Yasumitsu T, Nakagawa K, et al. p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung. Clin Cancer Res 1997;3:1831-1835.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1831-1835
-
-
Komiya, T.1
Hosono, Y.2
Hirashima, T.3
Masuda, N.4
Yasumitsu, T.5
Nakagawa, K.6
-
12
-
-
0037106265
-
Clinical significance of p21 expression in non-small-cell lung cancer
-
Shoji T, Tanaka F, Takata T, Yanagihara K, Otake Y, Hanaoka N, et al. Clinical significance of p21 expression in non-small-cell lung cancer. J Clin Oncol 2002;20:3865-3871.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3865-3871
-
-
Shoji, T.1
Tanaka, F.2
Takata, T.3
Yanagihara, K.4
Otake, Y.5
Hanaoka, N.6
-
13
-
-
0032886796
-
Overexpression of bax associated with mutations in the loop-sheet-helix motif of p53
-
Huang CL, Kohno N, Inufusa H, Kodama K, Taki T, Miyake M. Overexpression of bax associated with mutations in the loop-sheet-helix motif of p53. Am J Pathol 1999;155:955-965.
-
(1999)
Am J Pathol
, vol.155
, pp. 955-965
-
-
Huang, C.L.1
Kohno, N.2
Inufusa, H.3
Kodama, K.4
Taki, T.5
Miyake, M.6
-
14
-
-
0036697802
-
Establishment of a large cell lung cancer cell line (Y-ML-1B) producing granulocyte colony-stimulating factor
-
Sekido Y, Sato M, Usami N, Shigemitsu K, Mori S, Maeda O, et al. Establishment of a large cell lung cancer cell line (Y-ML-1B) producing granulocyte colony-stimulating factor. Cancer Genet Cytogenet 2002;137:33-42.
-
(2002)
Cancer Genet Cytogenet
, vol.137
, pp. 33-42
-
-
Sekido, Y.1
Sato, M.2
Usami, N.3
Shigemitsu, K.4
Mori, S.5
Maeda, O.6
-
16
-
-
0032446757
-
The possible role of apoptosis-suppressing genes, bcl-2 and mcl-1/EAT in human adrenal tumors
-
Ando T, Shibata H, Suzuki T, Kurihara I, Hayashi K, Hayashi M, et al. The possible role of apoptosis-suppressing genes, bcl-2 and mcl-1/EAT in human adrenal tumors. Endocr Res 1998;24:955-960.
-
(1998)
Endocr Res
, vol.24
, pp. 955-960
-
-
Ando, T.1
Shibata, H.2
Suzuki, T.3
Kurihara, I.4
Hayashi, K.5
Hayashi, M.6
-
17
-
-
0022504347
-
Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors
-
McCarty KS Jr, Szabo E, Flowers JL, Cox EB, Leight GS, Miller L, et al. Use of a monoclonal anti-estrogen receptor antibody in the immunohistochemical evaluation of human tumors. Cancer Res 1986;46:4244s-4248s.
-
(1986)
Cancer Res
, vol.46
-
-
McCarty Jr., K.S.1
Szabo, E.2
Flowers, J.L.3
Cox, E.B.4
Leight, G.S.5
Miller, L.6
-
18
-
-
0030932632
-
Mdm2 gene amplification and expression in non-small-cell lung cancer: Immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation
-
Higashiyama M, Doi O, Kodama K, Yokouchi H, Kasugai T, Ishiguro S, et al. Mdm2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation. Br J Cancer 1997;75:1302-1308.
-
(1997)
Br J Cancer
, vol.75
, pp. 1302-1308
-
-
Higashiyama, M.1
Doi, O.2
Kodama, K.3
Yokouchi, H.4
Kasugai, T.5
Ishiguro, S.6
-
19
-
-
0033946522
-
Mdm2 mRNA expression is a favorable prognostic factor in non-small-cell lung cancer
-
Ko JL, Cheng YW, Cheng SL, Su JM, Chen CY, Lee H. Mdm2 mRNA expression is a favorable prognostic factor in non-small-cell lung cancer. Int J Cancer 2000;89:265-270.
-
(2000)
Int J Cancer
, vol.89
, pp. 265-270
-
-
Ko, J.L.1
Cheng, Y.W.2
Cheng, S.L.3
Su, J.M.4
Chen, C.Y.5
Lee, H.6
-
20
-
-
0032535483
-
The ubiquitin-proteasome pathway: On protein death and cell life
-
Ciechanover A. The ubiquitin-proteasome pathway: on protein death and cell life. EMBO J 1998;17:7151-7160.
-
(1998)
EMBO J
, vol.17
, pp. 7151-7160
-
-
Ciechanover, A.1
-
22
-
-
0027427249
-
The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene
-
Papa FR, Hochstrasser M. The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature 1993;366:313-319.
-
(1993)
Nature
, vol.366
, pp. 313-319
-
-
Papa, F.R.1
Hochstrasser, M.2
-
23
-
-
0030598895
-
A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae
-
Moazed D, Johnson AD. A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae. Cell 1996;86:667-677.
-
(1996)
Cell
, vol.86
, pp. 667-677
-
-
Moazed, D.1
Johnson, A.D.2
-
24
-
-
0029939075
-
DUB-1, a deubiquitinating enzyme with growth suppressing activity
-
Zhu Y, Carroll M, Papa RF, Hochstrasser M, D'Andrea AD. DUB-1, a deubiquitinating enzyme with growth suppressing activity. Proc Natl Acad Sci U S A 1996;93:3275-3279.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3275-3279
-
-
Zhu, Y.1
Carroll, M.2
Papa, R.F.3
Hochstrasser, M.4
D'Andrea, A.D.5
-
25
-
-
0030895008
-
A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein
-
Everett RD, Meredith M, Orr A, Cross A, Kathoria M, Parkinson J. A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. EMBO J 1997;16:1519-1530.
-
(1997)
EMBO J
, vol.16
, pp. 1519-1530
-
-
Everett, R.D.1
Meredith, M.2
Orr, A.3
Cross, A.4
Kathoria, M.5
Parkinson, J.6
-
26
-
-
0348111469
-
Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP
-
Holowaty MN, Sheng Y, Nguyen T, Arrowsmith C, Frappier L. Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. J Biol Chem 2003;278:47753-47761.
-
(2003)
J Biol Chem
, vol.278
, pp. 47753-47761
-
-
Holowaty, M.N.1
Sheng, Y.2
Nguyen, T.3
Arrowsmith, C.4
Frappier, L.5
-
27
-
-
0037184947
-
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
-
Hu M, Li P, Li M, Li W, Yao T, Wu JW, et al. Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde. Cell 2002;111:1041-1054.
-
(2002)
Cell
, vol.111
, pp. 1041-1054
-
-
Hu, M.1
Li, P.2
Li, M.3
Li, W.4
Yao, T.5
Wu, J.W.6
-
28
-
-
11144354828
-
p53 apoptotic pathway molecules are frequently and simultaneously altered in nonsmall cell lung carcinoma
-
Mori S, Ito G, Usami N, Yoshioka H, Ueda Y, Kodama Y, et al. p53 apoptotic pathway molecules are frequently and simultaneously altered in nonsmall cell lung carcinoma. Cancer 2004;100:1673-1682.
-
(2004)
Cancer
, vol.100
, pp. 1673-1682
-
-
Mori, S.1
Ito, G.2
Usami, N.3
Yoshioka, H.4
Ueda, Y.5
Kodama, Y.6
-
29
-
-
0038068926
-
Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer
-
Kuroki T, Trapasso F, Yendamuri S, Matsuyama A, Alder H, Williams NN, et al. Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer. Cancer Res 2003;63:3352-3355.
-
(2003)
Cancer Res
, vol.63
, pp. 3352-3355
-
-
Kuroki, T.1
Trapasso, F.2
Yendamuri, S.3
Matsuyama, A.4
Alder, H.5
Williams, N.N.6
-
30
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D. p21 is a universal inhibitor of cyclin kinases. Nature 1993;366:701-704.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
31
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993;75:805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
32
-
-
15844397398
-
Diminished cell proliferation associated with the death-protective activity of Bcl-2
-
Borner C. Diminished cell proliferation associated with the death-protective activity of Bcl-2. J Biol Chem 1996;271:12695-12698.
-
(1996)
J Biol Chem
, vol.271
, pp. 12695-12698
-
-
Borner, C.1
-
33
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:609-619.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
34
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, et al. p53 status and the efficacy of cancer therapy in vivo. Science 1994;266:807-810.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
-
35
-
-
0033526357
-
Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer
-
Swisher SG, Roth JA, Nemunaitis J, Lawrence DD, Kemp BL, Carrasco CH, et al. Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. J Natl Cancer Inst 1999;91:763-771.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 763-771
-
-
Swisher, S.G.1
Roth, J.A.2
Nemunaitis, J.3
Lawrence, D.D.4
Kemp, B.L.5
Carrasco, C.H.6
|