Combination tetrathiomolybdate and radiation therapy in a mouse model of head and neck squamous cell carcinoma

Archives of Otolaryngology - Head and Neck Surgery

Volumn 132, Issue 3, 2006, Pages 333-338

  Khan, Mohamed K ^a   Mamou, Fatema ^b   Schipper, Matthew J ^b   May, Kerstin S ^b   Kwitny, Alla ^b   Warnat, Amber ^b   Bolton, Brian ^b   Nair, Bindu M ^a   Kariapper, Muhammed S T ^a   Miller, Meredith ^b   Brewer, George ^c   Normolle, Daniel ^b   Merajver, Sofia D ^c   Teknos, Theodoros N ^c  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERULOPLASMIN; TETRATHIOMOLYBDIC ACID;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HEAD AND NECK CARCINOMA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; SQUAMOUS CELL CARCINOMA; STATISTICAL ANALYSIS; TUMOR GROWTH; TUMOR VOLUME;

ANGIOGENESIS INHIBITORS; ANIMALS; CARCINOMA, SQUAMOUS CELL; CERULOPLASMIN; CHELATING AGENTS; COMBINED MODALITY THERAPY; HEAD AND NECK NEOPLASMS; MICE; MICE, INBRED C3H; MOLYBDENUM; RANDOM ALLOCATION;

EID: 33645228948     PISSN: 08864470     EISSN: 08864470     Source Type: Journal    
DOI: 10.1001/archotol.132.3.333     Document Type: Article

References (39)

1. Teicher BA, Holden SA, Dupuis NP, et al. Potentiation of cytotoxic therapies by TNP-470 and minocycline in mice bearing EMT-6 mammary carcinoma. Breast Cancer Res Treat. 1995;36:227-236.
2. Teicher BA, Holden SA, Ara G, et al. Influence of anti-angiogenic treatment on 9L gliosarcome: oxygenation and response to cytotoxic therapy. Int J Cancer. 1995;61:732-737.
3. Mauceri HJ, Hanna NN, Beckett MA, et al. Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature. 1998;394:287-291.
4. Gorski DH, Beckett MA, Jaskowiak NT, et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res. 1999;59:3374-3378.
5. Kishi K, Petersen S, Petersen C, et al. Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor. Cancer Res. 2000;60:1326-1331.
6. Brewer GJ, Hedera P, Kluin KJ, et al. Treatment of Wilson disease with ammonium tetrathiomolybdate, III: initial therapy in a total of 55 neurologically affected patients and follow-up with zinc therapy. Arch Neurol. 2003;60:379-385.
7. Brewer GJ. Copper control as an antiangiogenic anticancer therapy: lessons from treating Wilson's disease. Exp Biol Med (Maywood). 2001;226:665-673.
8. Brewer GJ, Merajver SD. Cancer therapy with tetrathiomolybdate: antiangiogenesis by lowering body copper - a review. Integr Cancer Ther. 2002;1:327-337.
9. Goodman VL, Brewer GJ, Merajver SD. Copper deficiency as an anti-cancer strategy. Endocr Relat Cancer. 2004;11:255-263.
10. Khan MK, Miller MW, Taylor J, et al. Radiotherapy and antiangiogenic TM in lung cancer. Neoplasia. 2002;4:164-170.
11. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1995;1:27-31.
12. Folkman J. Tumor angiogenesis. In: Holland JF, ed. Cancer Medicine. Vol 1. 4th ed. Baltimore, Md: Williams & Wilkins; 1996:181-204.
13. Kerbel RS. Tumor angiogenesis: past, present and the near future. Carcinogenesis. 2000;21:505-515.
14. Lopez-Graniel CM, Tamez de Leon D, Meneses-Garcia A, et al. Tumor angiogenesis as a prognostic factor in oral cavity carcinomas. J Exp Clin Cancer Res. 2001;20:463-468.
15. Smith BD, Smith GL, Carter D, Sasaki CT, Haffty BG. Prognostic significance of vascular endothelial growth factor protein levels in oral and oropharyngeal squamous cell carcinoma. J Clin Oncol. 2000;18:2046-2052.
16. Beatrice F, Cammarota R, Giordano C, et al. Angiogenesis: prognostic significance in laryngeal cancer. Anticancer Res. 1998;18(6B):4737-4740.
17. Williams JK, Carlson GW, Cohen C, Derose PB, Hunter S, Jurkiewicz MJ. Tumor angiogenesis as a prognostic factor in oral cavity tumors. Am J Surg. 1994;168:373-380.
18. Lin DT, Subbaramaiah K, Shah JP, Dannenberg AJ, Boyle JO. Cyclooxygenase-2: a novel molecular target for the prevention and treatment of head and neck cancer. Head Neck. 2002;24:792-799.
19. Franchi A, Gallo O, Paglierani M, et al. Inducible nitric oxide synthase expression in laryngeal neoplasia: correlation with angiogenesis. Head Neck. 2002; 24:16-23.
20. Solomon B, Hagekyriakou J, Trivett MK, Stacker SA, McArthur GA, Cullinane C. EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2003;55:713-723.
21. Wolf JS, Chen Z, Dong G, et al. IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. Clin Cancer Res. 2001;7:1812-1820.
22. Teknos TN, Cox C, Barrios MA, et al. Tumor angiogenesis as a predictive marker for organ preservation in patients with advanced laryngeal carcinoma. Laryngoscope. 2002;112:844-851.
23. Koukourakis MI, Giatromanolaki A, Sivridis E, et al. Squamous cell head and neck cancer: evidence of angiogenic regeneration during radiotherapy. Anticancer Res. 2001;21(6B):4301-4309.
24. Ito Y, Kamijo T, Yokose T, et al. Microvessel density predicts the radiosensitivity of metastatic head and neck squamous cell carcinoma in cervical lymph nodes. Int J Oncol. 2001;19:1127-1132.
25. Aebersold DM, Beer KT, Laissue J, et al. Intratumoral microvessel density predicts local treatment failure of radically irradiated squamous cell cancer of the oropharynx. Int J Radiat Oncol Biol Phys. 2000;48:17-25.
26. Zatterstrom UK, Brun E, Willen R, Kjellen E, Wennerberg J. Tumor angiogenesis and prognosis in squamous cell carcinoma of the head and neck. Head Neck. 1995;17:312-318.
27. Kamijo T, Yokose T, Hasebe T, et al. Image analysis of microvessel surface area predicts radiosensitivity in early-stage laryngeal carcinoma treated with radiotherapy. Clin Cancer Res. 2001;7:2809-2814.
28. Brun E, Zatterstrom U, Kjellen E, et al. Prognostic value of histopathological response to radiotherapy and microvessel density in oral squamous cell carcinomas. Acta Oncol. 2001;40:491-496.
29. Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996;86:353-364.
30. Pan Q, Kleer CG, van Golen KL, et al. Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis. Cancer Res. 2002;62:4854-4859.
31. Pan Q, Bao LW, Merajver SD. Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade. Mol Cancer Res. 2003;1:701-706.
32. Engleka KA, Maciag T. Inactivation of human fibroblast growth factor-1 (FGF-1) activity by interaction with copper ions involves FGF-1 dimer formation induced by copper-catalyzed oxidation. J Biol Chem. 1992;267:11307-11315.
33. Watanabe T, Seno M, Sasada R, Igarashi K. Molecular characterization of recombinant human acidic fibroblast growth factor produced in E. coli: comparative studies with human basic fibroblast growth factor. Mol Endocrinol. 1990;4:869-879.
34. Patstone G, Maher P. Copper and calcium binding motifs in the extracellular domains of fibroblast growth factor receptors. J Biol Chem. 1996;271:3343-3346.
35. Ziche M, Jones J, Gullino PM. Role of prostaglandin E1 and copper in angiogenesis. J Natl Cancer Inst. 1982;69:475-482.
36. Schosinsky KH, Lehmann HP, Beeler MF. Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride. Clin Chem. 1974;20:1556-1563.
37. Brewer GJ, Johnson V, Dick RD, Kluin KJ, Fink JK, Brunberg JA. Treatment of Wilson disease with ammonium tetrathiomolybdate, II: initial therapy in 33 neurologically affected patients and follow-up with zinc therapy. Arch Neurol. 1996;53:1017-1025.
38. Brewer GJ, Dick RD, Grover DK, et al. Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: phase I study. Clin Cancer Res. 2000;6:1-10.
39. Teknos TN, Islam M, Arenberg DA, et al. The effect of tetrathiomolybdate on cytokine expression, angiogenesis, and tumor growth in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg. 2005;131:204-211.