Site-directed mutagenes is to assess the binding capacity of class S protein of Staphylococcus aureus leucotoxins to the surface of polymorphonuclear cells

Journal of Biomedicine and Biotechnology

Volumn 2006, Issue , 2006, Pages

  Baba Moussa, L ^a   Werner, S ^b   Coraiola, M ^c   Colin, D A ^b   Keller, D ^b   Sanni, A ^a   Dalla Serra, M ^c   Monteil, H ^b   Prevost G ^b  

^a UNIVERSITY OF ABOMEY CALAVI   (Benin)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c ITC IRST   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; LEUKOTOXIN; PROTEIN S; STAPHYLOCOCCUS TOXIN; THREONINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; OLIGOMERIZATION; POLYMORPHONUCLEAR CELL; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; STAPHYLOCOCCUS AUREUS;

STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 33645227644     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/JBB/2006/80101     Document Type: Article

References (26)

1. Kloos WE, Bannerman TL. Staphylococcus and micrococcus. In: Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH, eds. Manual of Clinical Microbiology. 7th ed. Washington, DC: American Society for Microbiology Press; 1999:264-282.
2. Foster TJ, Höök M. Surface protein adhesins of Staphylococcus aureus. Trends in Microbiology. 1998;6(12):484-488.
3. Prévost G. The bi-component staphylococcal leucotoxins and γ-haemolysins (toxins). In: Alouf JE, Freer JH, eds. The Comprehensive Sourcebook of Bacterial Protein Toxins. London, UK: Academic Press; 1999:402-418.
4. Prévost G, Colin DA, Staali L, et al. Les leucotoxines formant des pores de Staphylococcus aureus: variabilité des cellulescibles et deux processus pharmacologiques [Pore-forming leukotoxins from Staphylococcus aureus: variability of the target cells and 2 pharmacological processes]. Pathologie Biologie. 1998;46(6):435-441.
5. Prévost G, Bouakham T, Piémont Y, Monteil H. Characterisation of a synergohymenotropic toxin produced by Staphylococcus intermedius. FEBS Letters. 1995;376(3):135-140.
6. Tomita T, Kamio Y. Molecular biology of the pore-forming cytolysins from Staphylococcus aureus, α- and γ-hemolysins and leukocidin. Bioscience, Biotechnology, and Biochemistry. 1997;61(4):565-572.
7. Cooney J, Kienle Z, Foster TJ, O'Toole PW. The gamma-hemolysin locus of Staphylococcus aureus comprises three linked genes, two of which are identical to the genes for the F and S components of leukocidin. Infection and Immunity. 1993;61(2):768-771.
8. Kaneko J, Kimura T, Kawakami Y, Tomita T, Kamio Y. Panton-Valentine leukocidin genes in a phage-like particle isolated from mitomycin C-treated Staphylococcus aureus V8 (ATCC 49775). Bioscience, Biotechnology, and Biochemistry. 1997;61(11):1960-1962.
9. Supersac G, Prévost G, Piémont Y. Sequencing of leucocidin R from Staphylococcus aureus P83 suggests that staphylococcal leucocidins and gamma-hemolysin are members of a single, two-component family of toxins. Infection and Immunity. 1993;61(2):580-587.
10. Gravet A, Baba Moussa L, Werner S, et al. Characterization of a novel 30%-distributed staphylococcal leucotoxin and structure comparison with the other members of the toxin family. In: Hacker J, Alouf JE, Brand BC, et al., eds. Bacterial Protein Toxins. Stuttgart, Germany: Gustav Fischer; 1998:401-402. Zentralblatt für Bakteriologie, Suppl. 29.
11. Gouaux E, Hobaugh M, Song L. α-Hemolysin, γ-hemolysin, and leukocidin from Staphylococcus aureus: distant in sequence but similar in structure. Protein Science. 1997;6(12): 2631-2635.
12. Prévost G, Mourey L, Colin DA, Menestrina G. Staphylococcal pore-forming toxins. In: van der Goot FG, Compans RW, Cooper M, et al., eds. Pore-Forming Toxins. Vol 257. 2001:53-83. Current Topics in Microbiology and Immunology.
13. Lesieur C, Vécsey-Semjén B, Abrami L, Fivaz M, van der Goot FG. Membrane insertion: the strategies of toxins. Molecular Membrane Biology. 1997;14(2):45-64.
14. Meunier O, Ferreras M, Supersac G, et al. A predicted β-sheet from class S components of staphylococcal γ-hemolysin is essential for the secondary interaction of the class F component. Biochimica et Biophysica Acta (BBA)/Biomembranes. 1997;1326(2):275-286.
15. Walker B, Bayley H. Key residues for membrane binding, oligomerization, and pore forming activity of staphylococcal alpha-hemolysin identified by cysteine scanning mutagenesis and targeted chemical modification. The Journal of Biological Chemistry. 1995;270(39):23065-23071.
16. 2+-activation from the pore-forming function of the bicomponent Panton-Valentine leucocidin in human PMNs. FEBS Letters. 1999;461(3):280-286.
17. Meunier O, Falkenrodt A, Monteil H, Colin DA. Application of flow cytometry in toxinology: pathophysiology of human polymorphonuclear leukocytes damaged by a pore-forming toxin from Staphylococcus aureus. Cytometry. 1995;21(3):241-247.
18. Gauduchon V, Werner S, Prévost G, Monteil H, Colin DA. Flow cytometric determination of Panton-Valentine leucocidin S component binding. Infection and Immunity. 2001; 69(4):2390-2395.
19. Byler DM, Susi H. Examination of the secondary structure of proteins by deconvolved FTIR spectra. Biopolymers. 1986; 25(3):469-487.
20. Prévost G, Supersac G, Colin DA, et al. The new family of leucotoxins from Staphylococcus aureus: structural and biological properties. In: Alouf JE, Freer J, Aitken R, Boulnois G, eds. Bacterial Protein Toxins. Stuttgart, Germany: Gustav Fischer; 1994:284-293. Zentralblatt für Bakteriologie, Suppl. 24.
21. Pédelacq J-D, Maveyraud L, Prévost G, et al. The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins. Structure. 1999;7(3):277-287.
22. Guillet V, Roblin P, Werner S, et al. Crystal structure of leucotoxin S component: new insight into the Staphylococcal β-barrel pore-forming toxins. The Journal of Biological Chemistry. 2004;279(39):41028-41037.
23. 2+ channels in the membrane of human polymorphonuclear neutrophils. Journal of Membrane Biology. 1998;162(3):209-216.
24. Colin DA, Mazurier I, Sire S, Finck-Barbançon V. Interaction of the two components of leukocidin from Staphylococcus aureus with human polymorphonuclear leukocyte membranes: sequential binding and subsequent activation. Infection and Immunity. 1994;62(8):3184-3188.
25. Olson R, Nariya H, Yokota K, Kamio Y, Gouaux E. Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel. Nature Structural Biology. 1999;6(2):134-140.
26. Menzies BE, Kernodle DS. Site-directed mutagenesis of the alpha-toxin gene of Staphylococcus aureus: role of histidines in toxin activity in vitro and in a murine model. Infection and Immunity. 1994;62(5):1843-1847.