Circulating heat shock protein 60 is associated with early cardiovascular disease

Hypertension

Volumn 36, Issue 2, 2000, Pages 303-307

  Pockley, A Graham ^a   Wu, Ruhia ^b   Lemne, Carola ^b   Kiessling, Rolf ^c   De Faire, Ulf ^b   Frostegård, Johan ^b  

^a NORTHERN GENERAL HOSPITAL   (United Kingdom)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Atherosclerosis; Heat shock; Human; Hypertension,borderline; Proteins

Indexed keywords

CHOLESTEROL; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; PROTEIN ANTIBODY; TRIACYLGLYCEROL;

ADULT; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DEMOGRAPHY; DIASTOLIC BLOOD PRESSURE; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MASS SCREENING; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0033903935     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.36.2.303     Document Type: Article

References (44)

1. Is atherosclerosis an immunologically mediated disease?
2. Role of Hsp60 during autoimmune and bacterial inflammation
3. Heat shock, stress proteins, chaperones and proteotoxicity
4. Stress proteins may provide a link between the immune response to infection and autoimmunity
5. Association of serum antibodies to heat shock protein 65 with carotid atherosclerosis
6. Changes of serum antibodies to heat-shock protein 65 in coronary heart disease and acute myocardial infarction
7. Association of serum antibodies to heat-shock protein 65 with borderline hypertension
8. Surface expression by mononuclear phagocytes of an epitope shared with mycobacterial heat shock protein 60
9. Surface expressed heat-shock proteins by stressed or human immunodeficiency vires (HIV)-infected lymphoid cells represent the target for antibody-dependent cellular cytotoxicity
10. Surface staining and cytotoxic activity of heat-shock protein 60 in stressed aortic endothelial cells
11. Selective release from cultured mammalian cells of heat-shock (stress) proteins that resemble glia-axon transfer proteins
12. Heat shock protein studies in type 1 and type 2 diabetes and human islet cell culture
13. Identification of human heat shock protein 60 (Hsp60) and anti-Hsp60 antibodies in the peripheral circulation of normal individuals
14. Detection of heat shock protein 70 (Hsp70) and anti-Hsp70 antibodies in the serum of normal individuals
15. Carotid intima-media thickness and plaque in borderline hypertension
16. Antibodies to endothelial cells in borderline hypertension
17. Antibodies to Mycobacterial 65 kDa heat shock protein in systemic sclerosis (scleroderma)
18. Lipoprotein fractionation
19. Dyslipoproteinemic changes in borderline hypertension
20. Immunology of atherosclerosis: Demonstration of hsp60 expression and T lymphocytes bearing αβ or γδ receptor in human atherosclerotic lesions
21. Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65
22. Autoantibodies against heat shock protein mediate endothelial cytotoxicity
23. Epitope specificity of anti-heat shock protein 65/60 serum antibodies in atherosclerosis
24. The effects of hypertension on cerebral atherosclerosis in the cynomolgus monkey
25. A prospective, in vivo study of the relationship between blood flow haemodynamics and atherosclerosis in a hyperlipidemic swine model
26. Risk factors and atherosclerotic lesions: A review of autopsy studies
27. Thermosensitivity, a possible new locus involved in genetic hypertension
28. Restriction fragment length polymorphism of hsp70 gene, localized in the RT1 complex, is associated with hypertension in spontaneously hypertensive rats
29. Expression of hsp70 gene in lymphocytes from normotensive and hypertensive humans
30. Stress proteins in atherogenesis
31. Effect of heat shock proteins on survival of isolated aortic cells from normal and atherosclerotic cynomolgus macaques
32. Exogenous Hsp70 becomes cell associated, but not internalised by stressed arterial smooth muscle cells
33. Immune responses in atherosclerosis
34. Cytokine expression in advanced human atherosclerotic plaques: Dominance of proinflammatory (Th1) and macrophage-stimulating cytokines
35. Expression of a heat inducible gene of the Hsp70 family in myelomonocytic cells: Regulation by bacterial products and cytokines
36. Induction of human Hsp60 expression in monocytic cell lines
37. Cytokines induce stress protein formation in cultured cardiac myocytes
38. Cytokine induction of heat shock protein expression in human oligodendrocytes: An interleukin-1-mediated mechanism
39. Induction of heat shock protein in monocytic cells by oxidised low density lipoprotein
40. Cytokine and adhesion molecule expression in human monocytes and endothelial cells stimulated with bacterial heat shock proteins
41. Bacterial heat shock proteins directly induce cytokine mRNA and interleukin-1 secretion in macrophage cultures
42. Mycobacterial heat shock protein 65 induces proinflammatory cytokines but does not activate human mononuclear phagocytes
43. Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages
44. Oxidised-LDL induce the expression of heat shock protein 70 in human endothelial cells