The crystal structure of the R52Q mutant demonstrates a role for R52 in chromophore pKa regulation in photoactive yellow protein

Biochemistry

Volumn 45, Issue 11, 2006, Pages 3542-3547

  Shimizu, Nobutaka ^b   Kamikubo, Hironari ^a   Yamazaki, Yoichi ^a   Imamoto, Yasushi ^a   Kataoka, Mikio ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b JAPAN SYNCHROTRON RADIATION RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CHROMOPHORES; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; HYDROGEN BONDS; PH EFFECTS; PROTEINS;

CHROMOPHORE BINDING POCKET; CONFORMATIONAL CHANGES; PHOTOACTIVE YELLOW PROTEIN (PYP); WATER MOLECULES;

MUTAGENESIS;

ARGININE; GLUTAMINE; GUANIDINE DERIVATIVE; MUTANT PROTEIN; PHOTOACTIVE YELLOW PROTEIN; SOLVENT; WATER;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HYDROGEN BOND; MUTATION; PKA; PRIORITY JOURNAL; REGULATORY MECHANISM; WILD TYPE; X RAY CRYSTALLOGRAPHY;

ARGININE; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GLUTAMINE; GUANIDINE; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; PHOTORECEPTORS, MICROBIAL; PROTEIN CONFORMATION; WATER;

EID: 33645214376     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051430a     Document Type: Article

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