Elimination of abnormal sialylglycoproteins in fibroblasts with sialidosis and galactosialidosis by normal gene transfer and enzyme replacement

Glycobiology

Volumn 16, Issue 4, 2006, Pages 271-280

  Oheda, Yukako ^a   Kotani, Masaharu ^b   Murata, Mai ^b,c   Sakuraba, Hitoshi ^b,c   Kadota, Yoshito ^a   Tatano, Yutaka ^a,c   Kuwahara, Jun ^a   Itoh, Kohji ^a,c  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Galactosialidosis; Maackia amurensis lectin; Molecular therapy; Sialidosis; Sialylglycoprotein

Indexed keywords

BETA GALACTOSIDASE; CARBOXYPEPTIDASE C; COMPLEMENTARY DNA; ENZYME PRECURSOR; GLYCOCONJUGATE; GLYCOPEPTIDASE; HYALURONIC ACID; HYBRID PROTEIN; LECTIN; OLIGOSACCHARIDE; RECOMBINANT ENZYME; SIALIDASE; SIALOGLYCOPROTEIN;

ARTICLE; BIOASSAY; CONJUGATION; CONTROLLED STUDY; DIAGNOSTIC VALUE; ENZYME ACTIVITY; ENZYME REPLACEMENT; EXPRESSION VECTOR; FIBROBLAST CULTURE; FLUORESCENCE ANALYSIS; GALACTOSIALIDOSIS; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LYSOSOME STORAGE DISEASE; MAACKIA; PLASMID VECTOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN GLYCOSYLATION; SIALIDOSIS; WESTERN BLOTTING;

CARBOXYPEPTIDASE C; CELLS, CULTURED; EVALUATION STUDIES; FIBROBLASTS; GENE THERAPY; HUMANS; MUCOLIPIDOSES; NEURAMINIDASE; OLIGOSACCHARIDES; PROTEIN MODIFICATION, TRANSLATIONAL; RECOMBINANT FUSION PROTEINS; SIALOGLYCOPROTEINS; TRANSFECTION;

MAACKIA; MAACKIA AMURENSIS;

EID: 33645110218     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwj069     Document Type: Article

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