Farnesol induces thyroid hormone receptor (THR) β1 but inhibits THR-mediated signaling in MCF-7 human breast cancer cells

Biochemical and Biophysical Research Communications

Volumn 343, Issue 1, 2006, Pages 239-243

  Duncan, Robin E ^a,b   Archer, Michael C ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Farnesol; Glycerol 3 phosphate dehydrogenase 1; Malic enzyme; MCF 7 human breast cancer cells; Proliferation; Sodium iodide symporter; Spot 14; Thyroid hormone receptor 1

Indexed keywords

FARNESOL; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE; THYROID HORMONE RECEPTOR BETA;

ARTICLE; BREAST CANCER; CANCER CELL; CELL GROWTH; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BREAST NEOPLASMS; CELL LINE, TUMOR; DNA; FARNESOL; GENE EXPRESSION REGULATION; HUMANS; RESPONSE ELEMENTS; RNA, MESSENGER; SIGNAL TRANSDUCTION; THYROID HORMONE RECEPTORS BETA;

MINK CELL FOCUS-FORMING VIRUS;

EID: 33645102823     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.02.145     Document Type: Article

References (23)

1. D. Tatman, and H. Mo Volatile isoprenoid constituents of fruits, vegetables and herbs cumulatively suppress the proliferation of murine B16 melanoma and human HL-60 leukemia cells Cancer Lett. 175 2002 129 139
2. T.E. Meigs, and R.D. Simoni Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase Arch. Biochem. Biophys. 345 1997 1 9
3. I. Adany, E.M. Yazlovitskaya, J.S. Haug, P.A. Voziyan, and G. Melnykovych Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically- derived cells in culture Cancer Lett. 79 1994 175 179
4. J.A. McAnally, M. Jung, and H. Mo Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells Cancer Lett. 202 2003 181 192
5. Y.D. Burke, A.S. Ayoubi, S.R. Werner, B.C. McFarland, D.K. Heilman, B.A. Ruggeri, and P.L. Crowell Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention Anticancer Res. 22 2002 3127 3134
6. K. Miquel, A. Pradines, and G. Favre Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells Biochem. Biophys. Res. Commun. 225 1996 869 876
7. C.V. Rao, H.L. Newmark, and B.S. Reddy Chemopreventive effect of farnesol and lanosterol on colon carcinogenesis Cancer Detect. Prev. 26 2002 419 425
8. B.M. Forman, E. Goode, J. Chen, A.E. Oro, D.J. Bradley, T. Perlmann, D.J. Noonan, L.T. Burka, T. McMorris, and W.W. Lamph Identification of a nuclear receptor that is activated by farnesol metabolites Cell 81 1995 687 693
9. N. Takahashi, T. Kawada, T. Goto, T. Yamamoto, A. Taimatsu, N. Matsui, K. Kimura, M. Saito, M. Hosokawa, K. Miyashita, and T. Fushiki Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes FEBS Lett. 514 2002 315 322
10. A. Aranda, and A. Pascual Nuclear hormone receptors and gene expression Physiol. Rev. 81 2001 1269 1304
11. R.J. Gillies, N. Didier, and M. Denton Determination of cell number in monolayer cultures Anal. Biochem. 159 1986 109 113
12. W. Huang, C. Wood, M.R. L'Abbe, G.S. Gilani, K.A. Cockell, and C.W. Xiao Soy protein isolate increases hepatic thyroid hormone receptor content and inhibits its binding to target genes in rats J. Nutr. 135 2005 1631 1635
13. P. Narayan, C.W. Liaw, and H.C. Towle Rapid induction of a specific nuclear mRNA precursor by thyroid hormone Proc. Natl. Acad. Sci. USA 81 1984 4687 4691
14. J.A. Franklyn, S. King, J.A. Ahlquist, and M.C. Sheppard Effect of hypothyroidism and thyroid hormone treatment of the rat on hepatic Spot 14 and thyroxine binding prealbumin mRNAs Acta Endocrinol. (Copenh) 121 1989 383 388
15. C. Gonzalez-Manchon, N. Butta, M. Ferrer, M.S. Ayuso, and R. Parrilla Molecular cloning and functional characterization of the human cytosolic malic enzyme promoter: thyroid hormone responsiveness DNA Cell Biol. 16 1997 533 544
16. J.M. Tibaldi, N. Sahnoun, and M.I. Surks Response of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme to constant infusions of l-triiodothyronine in rats bearing the Walker 256 carcinoma. Evidence for divergent postreceptor regulation of the thyroid hormone response J. Clin. Invest. 74 1984 705 714
17. - symporter mediates iodide uptake in breast cancer metastases and can be selectively down-regulated in the thyroid Clin. Cancer Res. 10 2004 4294 4302
18. C. Spitzweg, W. Joba, J.C. Morris, and A.E. Heufelder Regulation of sodium iodide symporter gene expression in FRTL-5 rat thyroid cells Thyroid 9 1999 821 830
19. Y. de Launoit, and R. Kiss Influence of l-thyroxine, l-triiodothyronine, thyroid stimulating hormone, or estradiol on the cell kinetics of cultured mammary cancer cells In Vitro Cell Dev. Biol. 25 1989 585 591
20. C.R. Nogueira, and M.M. Brentani Triiodothyronine mimics the effects of estrogen in breast cancer cell lines J. Steroid Biochem. Mol. Biol. 59 1996 271 279
21. H.Y. Tang, H.Y. Lin, S. Zhang, F.B. Davis, and P.J. Davis Thyroid hormone causes mitogen-activated protein kinase-dependent phosphorylation of the nuclear estrogen receptor Endocrinology 145 2004 3265 3272
22. F. Zhou-Li, V. Albaladejo, M.O. Joly-Pharaboz, B. Nicolas, and J. Andre Antiestrogens prevent the stimulatory effects of l-triiodothyronine on cell proliferation Endocrinology 130 1992 1145 1152
23. B.A. Cunningham, J.T. Moncur, J.T. Huntington, and W.B. Kinlaw "Spot 14" protein: a metabolic integrator in normal and neoplastic cells Thyroid 8 1998 815 825