-
1
-
-
0018747713
-
The influence of old age and of renal failure on hepatic glucuronidation in the rat
-
Ali M, Nicholls PJ, and Yoosuf A (1979) The influence of old age and of renal failure on hepatic glucuronidation in the rat. Br J Pharmacol 66:498P-499P.
-
(1979)
Br J Pharmacol
, vol.66
-
-
Ali, M.1
Nicholls, P.J.2
Yoosuf, A.3
-
2
-
-
0019182003
-
Metabolism of drugs by the kidney
-
Anders MW (1980) Metabolism of drugs by the kidney. Kidney Int 18:636-647.
-
(1980)
Kidney Int
, vol.18
, pp. 636-647
-
-
Anders, M.W.1
-
3
-
-
0019291189
-
Influence of renal failure on the hepatic clearance of bufuralol in man
-
Balant L, Francis RJ, Tozer TN, Marmy A, Tschopp JM, and Fabre J (1980) Influence of renal failure on the hepatic clearance of bufuralol in man. J Pharmacokinet Biopharm 8:421-438.
-
(1980)
J Pharmacokinet Biopharm
, vol.8
, pp. 421-438
-
-
Balant, L.1
Francis, R.J.2
Tozer, T.N.3
Marmy, A.4
Tschopp, J.M.5
Fabre, J.6
-
4
-
-
0029923354
-
Glucuronidation of diflunisal in liver and kidney microsomes of rat and man
-
Brunelle FM and Verbeeck RK (1996) Glucuronidation of diflunisal in liver and kidney microsomes of rat and man. Xenobiotica 26:123-131.
-
(1996)
Xenobiotica
, vol.26
, pp. 123-131
-
-
Brunelle, F.M.1
Verbeeck, R.K.2
-
5
-
-
0023095427
-
Purification and properties of rat kidney UDP-glucuronosyltransferase
-
Coughtrie MW, Burchell B, and Bend JR (1987) Purification and properties of rat kidney UDP-glucuronosyltransferase. Biochem Pharmacol 36:245-251.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 245-251
-
-
Coughtrie, M.W.1
Burchell, B.2
Bend, J.R.3
-
6
-
-
0020858720
-
Separation, purification and characterization of three isoenzymes of UDP-glucuronyltransferase from rat liver microsomes
-
Falany CN and Tephly TR (1983) Separation, purification and characterization of three isoenzymes of UDP-glucuronyltransferase from rat liver microsomes. Arch Biochem Biophys 227:248-258.
-
(1983)
Arch Biochem Biophys
, vol.227
, pp. 248-258
-
-
Falany, C.N.1
Tephly, T.R.2
-
7
-
-
0035209568
-
The role of hepatic and extrahepatic UDP-glucuronosyltransferase in human drug metabolism
-
Fisher MB, Paine MF, Strelevitz TJ, and Wrighton SA (2001) The role of hepatic and extrahepatic UDP-glucuronosyltransferase in human drug metabolism. Drug Metab Rev 33:273-297.
-
(2001)
Drug Metab Rev
, vol.33
, pp. 273-297
-
-
Fisher, M.B.1
Paine, M.F.2
Strelevitz, T.J.3
Wrighton, S.A.4
-
8
-
-
0022885624
-
Renal disease and drug metabolism: An overview
-
Gibson TP (1986) Renal disease and drug metabolism: an overview. Am J Kidney Dis 8:7-17.
-
(1986)
Am J Kidney Dis
, vol.8
, pp. 7-17
-
-
Gibson, T.P.1
-
9
-
-
0035076242
-
Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection
-
Hanioka N, Jinno H, Tanaka-Kagawa T, Nishimura T, and Ando M (2001) Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection. J Pharm Biomed Anal 25:65-75.
-
(2001)
J Pharm Biomed Anal
, vol.25
, pp. 65-75
-
-
Hanioka, N.1
Jinno, H.2
Tanaka-Kagawa, T.3
Nishimura, T.4
Ando, M.5
-
10
-
-
0035029212
-
Epirubicin glucuronidation is catalyzed by human UDP- glucuronosyltransferase 2B7
-
Innocenti F, Iyer L, Ramirez J, Green MD, and Ratain MJ (2001) Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7. Drug Metab Dispos 29:686-692.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 686-692
-
-
Innocenti, F.1
Iyer, L.2
Ramirez, J.3
Green, M.D.4
Ratain, M.J.5
-
11
-
-
0028092131
-
Purification of a phenobarbital-inducible morphine UDP- glucuronosyltransferase isoform, absent from Gunn rat liver
-
Ishii Y, Tsuruda K, Tanaka M, and Oguri K (1994) Purification of a phenobarbital-inducible morphine UDP-glucuronosyltransferase isoform, absent from Gunn rat liver. Arch Biochem Biophys 315:345-351.
-
(1994)
Arch Biochem Biophys
, vol.315
, pp. 345-351
-
-
Ishii, Y.1
Tsuruda, K.2
Tanaka, M.3
Oguri, K.4
-
12
-
-
0033102535
-
The significance of amino acid residue Asp446 for enzymatic stability of rat UDP-glucuronosyltranferase UGT1A6
-
Iwano H, Yokota H, Ohgiya S, and Yuasa A (1999) The significance of amino acid residue Asp446 for enzymatic stability of rat UDP-glucuronosyltranferase UGT1A6. Arch Biochem Biophys 363:116-120.
-
(1999)
Arch Biochem Biophys
, vol.363
, pp. 116-120
-
-
Iwano, H.1
Yokota, H.2
Ohgiya, S.3
Yuasa, A.4
-
13
-
-
0026517062
-
New developments in glucuronidation research: Report of a workshop on "glucuronidation, its role in health and disease"
-
Jansen PL, Mulder GJ, Burchell B, and Bock KW (1992) New developments in glucuronidation research: report of a workshop on "glucuronidation, its role in health and disease". Hepatology 15:532-544.
-
(1992)
Hepatology
, vol.15
, pp. 532-544
-
-
Jansen, P.L.1
Mulder, G.J.2
Burchell, B.3
Bock, K.W.4
-
14
-
-
0034081480
-
The glucuronidation of morphine by dog liver microsomes: Identification of morphine-6-O-glucuronide
-
King C, Finley B, and Franklin R (2000) The glucuronidation of morphine by dog liver microsomes: identification of morphine-6-O-glucuronide. Drug Metab Dispos 28:661-663.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 661-663
-
-
King, C.1
Finley, B.2
Franklin, R.3
-
15
-
-
0030221217
-
The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1
-
King CD, Green MD, Rios GR, Coffman BL, Owens IS, Bishop WP, and Tephly TR (1996) The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1. Arch Biochem Biophys 332:92-100.
-
(1996)
Arch Biochem Biophys
, vol.332
, pp. 92-100
-
-
King, C.D.1
Green, M.D.2
Rios, G.R.3
Coffman, B.L.4
Owens, I.S.5
Bishop, W.P.6
Tephly, T.R.7
-
16
-
-
0031034450
-
Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds
-
King CD, Rios GR, Green MD, Mackenzie PI, and Tephly TR (1997) Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds. Drug Metab Dispos 25:251-255.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 251-255
-
-
King, C.D.1
Rios, G.R.2
Green, M.D.3
Mackenzie, P.I.4
Tephly, T.R.5
-
17
-
-
0017358161
-
Microsomal enzymes in malnutrition as determined by plasma half life of antipyrine
-
Krishnaswamy K and Naidu AN (1977) Microsomal enzymes in malnutrition as determined by plasma half life of antipyrine. Br Med J 26:538-540.
-
(1977)
Br Med J
, vol.26
, pp. 538-540
-
-
Krishnaswamy, K.1
Naidu, A.N.2
-
18
-
-
0035146107
-
Down-regulation of hepatic cytochrome P450 in chronic renal failure
-
Leblond F, Guevin C, Demers C, Pellerin I, Gascon-Barre M, and Pichette V (2001) Down-regulation of hepatic cytochrome P450 in chronic renal failure. J Am Soc Nephrol 12:326-332.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 326-332
-
-
Leblond, F.1
Guevin, C.2
Demers, C.3
Pellerin, I.4
Gascon-Barre, M.5
Pichette, V.6
-
20
-
-
0029089659
-
Glucuronidation of propofol in microsomal fractions from various tissues and species including humans: Effect of different drugs
-
Le Guellec C, Lacarelle B, Villard PH, Point H, Catalin J, and Durand A (1995) Glucuronidation of propofol in microsomal fractions from various tissues and species including humans: effect of different drugs. Anesth Analg 81:855-861.
-
(1995)
Anesth Analg
, vol.81
, pp. 855-861
-
-
Le Guellec, C.1
Lacarelle, B.2
Villard, P.H.3
Point, H.4
Catalin, J.5
Durand, A.6
-
21
-
-
6344248683
-
Specificity and regioselectivity of the conjugation of estradiol, estrone and their catecholestrogen and methoxyestrogen metabolites by human uridine diphosphoglucuronosyltransferases expressed in endometrium
-
Lepine J, Bernard O, Plante M, Tetu B, Pelletier G, Labrie F, Belanger A, and Guillemette C (2004) Specificity and regioselectivity of the conjugation of estradiol, estrone and their catecholestrogen and methoxyestrogen metabolites by human uridine diphosphoglucuronosyltransferases expressed in endometrium. J Clin Endocrinol Metab 89:5222-5232.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5222-5232
-
-
Lepine, J.1
Bernard, O.2
Plante, M.3
Tetu, B.4
Pelletier, G.5
Labrie, F.6
Belanger, A.7
Guillemette, C.8
-
22
-
-
0028904918
-
Increased oxidation and decreased conjugation of drugs in the liver caused by starvation. Altered metabolism of certain aromatic compounds and acetone
-
Mandl J, Banhegyi G, Kalapos MP, and Garzo T (1995) Increased oxidation and decreased conjugation of drugs in the liver caused by starvation. Altered metabolism of certain aromatic compounds and acetone. Chem Biol Interact 96:87-101.
-
(1995)
Chem Biol Interact
, vol.96
, pp. 87-101
-
-
Mandl, J.1
Banhegyi, G.2
Kalapos, M.P.3
Garzo, T.4
-
23
-
-
24944515352
-
An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: Evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity
-
Miles KK, Stern ST, Smith PC, Kessler F, Ali S, and Ritter J (2005) An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity. Drug Metab Dispos 33:1513-1520.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1513-1520
-
-
Miles, K.K.1
Stern, S.T.2
Smith, P.C.3
Kessler, F.4
Ali, S.5
Ritter, J.6
-
25
-
-
0024994625
-
Conjugation of chemical carcinogens by primary cultures of human hepatocytes
-
Monteith DK, Michalopoulos G, and Strom SC (1990) Conjugation of chemical carcinogens by primary cultures of human hepatocytes. Xenobiotica 20:753-763.
-
(1990)
Xenobiotica
, vol.20
, pp. 753-763
-
-
Monteith, D.K.1
Michalopoulos, G.2
Strom, S.C.3
-
26
-
-
0034094062
-
Determination of the kinetics of rat UDPglucuronosyltransferases (UGTs) in liver and intestine using HPLC
-
Narayanan R, LeDuc B, and Williams DA (2000) Determination of the kinetics of rat UDPglucuronosyltransferases (UGTs) in liver and intestine using HPLC. J Pharm Biomed Anal 22:527-540.
-
(2000)
J Pharm Biomed Anal
, vol.22
, pp. 527-540
-
-
Narayanan, R.1
LeDuc, B.2
Williams, D.A.3
-
27
-
-
0023858335
-
Immunocharacterization of UDP-glucuronosyltransferases isoenzymes in human liver, intestine and kidney
-
Peters WHM and Jansent PLM (1988) Immunocharacterization of UDP-glucuronosyltransferases isoenzymes in human liver, intestine and kidney. Biochem Pharmacol 37:564-567.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 564-567
-
-
Peters, W.H.M.1
Jansent, P.L.M.2
-
28
-
-
0028044817
-
A recombinant phenobarbital-inducible rat liver UDP- glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols and carboxylic acids
-
Pritchard M, Fournel-Gigleux S, Siest G, Mackenzie P, and Magdalou J (1993) A recombinant phenobarbital-inducible rat liver UDP- glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols and carboxylic acids. Mol Pharmacol 45:42-50.
-
(1993)
Mol Pharmacol
, vol.45
, pp. 42-50
-
-
Pritchard, M.1
Fournel-Gigleux, S.2
Siest, G.3
Mackenzie, P.4
Magdalou, J.5
-
29
-
-
0142074311
-
Down-regulation of hepatic CYP3A in chronic renal insufficiency
-
Rege B, Krieg R, Gao N, and Sarkar MA (2003) Down-regulation of hepatic CYP3A in chronic renal insufficiency. Pharm Res (NY) 20:1600-1606.
-
(2003)
Pharm Res (NY)
, vol.20
, pp. 1600-1606
-
-
Rege, B.1
Krieg, R.2
Gao, N.3
Sarkar, M.A.4
-
30
-
-
0034534895
-
Role of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions
-
Ritter JK (2000) Role of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions. Chem Biol Interact 129:171-193.
-
(2000)
Chem Biol Interact
, vol.129
, pp. 171-193
-
-
Ritter, J.K.1
-
31
-
-
0032791711
-
Expression and inducibility of the human bilirubin UDP- glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: Evidence for both genetic and environmental influences
-
Ritter JK, Kessler FK, Thompson MT, Grove AD, Auyeung DJ, and Fisher RA (1999) Expression and inducibility of the human bilirubin UDP- glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: evidence for both genetic and environmental influences. Hepatology 30:476-484.
-
(1999)
Hepatology
, vol.30
, pp. 476-484
-
-
Ritter, J.K.1
Kessler, F.K.2
Thompson, M.T.3
Grove, A.D.4
Auyeung, D.J.5
Fisher, R.A.6
-
32
-
-
0026508999
-
Characterization of human liver cytochromes P-450 involved in theophylline metabolism
-
Sarkar MA, Hunt C, Guzelian PS, and Karnes HT (1992) Characterization of human liver cytochromes P-450 involved in theophylline metabolism. Drug Metab Dispos 20:31-37.
-
(1992)
Drug Metab Dispos
, vol.20
, pp. 31-37
-
-
Sarkar, M.A.1
Hunt, C.2
Guzelian, P.S.3
Karnes, H.T.4
-
33
-
-
0027991904
-
Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation
-
Senafi SB, Clarke DJ, and Burchell B (1994) Investigation of the substrate specificity of a cloned expressed human bilirubin UDP- glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation. Biochem J 303:233-240.
-
(1994)
Biochem J
, vol.303
, pp. 233-240
-
-
Senafi, S.B.1
Clarke, D.J.2
Burchell, B.3
-
35
-
-
0024416484
-
Zidovudine disposition in patients with severe renal impairment: Influence of hemodialysis
-
Singlas E, Pioger JC, Taburet AM, Colin JN, and Fillastre JP (1989) Zidovudine disposition in patients with severe renal impairment: influence of hemodialysis. Clin Pharmacol Ther 46:190-197.
-
(1989)
Clin Pharmacol Ther
, vol.46
, pp. 190-197
-
-
Singlas, E.1
Pioger, J.C.2
Taburet, A.M.3
Colin, J.N.4
Fillastre, J.P.5
-
36
-
-
0025284207
-
UDP-glucuronosyltransferases: A family of detoxifying enzymes
-
Tephly TR and Burchell B (1990) UDP-glucuronosyltransferases: a family of detoxifying enzymes. Trends Pharmacol Sci 11:276-279.
-
(1990)
Trends Pharmacol Sci
, vol.11
, pp. 276-279
-
-
Tephly, T.R.1
Burchell, B.2
-
37
-
-
0025757336
-
The effect of renal failure on hepatic drug clearance
-
Touchette MA and Slaughter RL (1991) The effect of renal failure on hepatic drug clearance. DICP-Ann Pharmacother 25:1214-1224.
-
(1991)
DICP-Ann Pharmacother
, vol.25
, pp. 1214-1224
-
-
Touchette, M.A.1
Slaughter, R.L.2
-
38
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression and disease
-
Tukey RH and Strassburg CP (2000) Human UDP-glucuronosyltransferases: metabolism, expression and disease. Annu Rev Pharmacol Toxicol 40:581-616.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
39
-
-
0035103197
-
Relative enzymatic activity, protein stability and tissue distribution of human steroid-metabolizing UGT2B subfamily members
-
Turgeon D, Carrier JS, Levesque E, Hum DW, and Belanger A (2001) Relative enzymatic activity, protein stability and tissue distribution of human steroid-metabolizing UGT2B subfamily members. Endocrinology 142:778-787.
-
(2001)
Endocrinology
, vol.142
, pp. 778-787
-
-
Turgeon, D.1
Carrier, J.S.2
Levesque, E.3
Hum, D.W.4
Belanger, A.5
-
40
-
-
0029978949
-
Influence of diet and nutritional status on drug metabolism
-
Walter-Sack I and Klotz U (1996) Influence of diet and nutritional status on drug metabolism. Clin Pharmacokinet 31:47-64.
-
(1996)
Clin Pharmacokinet
, vol.31
, pp. 47-64
-
-
Walter-Sack, I.1
Klotz, U.2
|