Increased stress protein ORP150 autoantibody production in Type 1 diabetic patients

Diabetic Medicine

Volumn 23, Issue 2, 2006, Pages 216-219

  Nakatani, Y ^a   Kaneto, H ^a   Hatazaki, M ^a   Yoshiuchi, K ^a   Kawamori, D ^a   Sakamoto, K ^a   Matsuoka, T ^a   Ogawa, S ^b   Yamasaki, Y ^a   Matsuhisa, M ^a,c  

^a OSAKA UNIVERSITY   (Japan)

^b KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

ER Stress; ORP150; Type 1 DM

Indexed keywords

AUTOANTIBODY; HEAT SHOCK PROTEIN; OXYGEN REGULATED PROTEIN 150; PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOPLASMIC RETICULUM; FEMALE; FOLLOW UP; GENE OVEREXPRESSION; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; LIVER; MAJOR CLINICAL STUDY; MALE; STRESS;

ADULT; AUTOANTIBODIES; CHRONIC DISEASE; DIABETES MELLITUS, TYPE 1; ENDOPLASMIC RETICULUM; FEMALE; HUMANS; INFLAMMATION; MALE; MOLECULAR CHAPERONES; OXYGEN; PROTEINS; STRESS;

EID: 33645080433     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2005.01766.x     Document Type: Article

References (12)

1. Aridor M Balch WE Integration of endoplasmic reticulum signaling in health and disease Nat Med 1999 5 745 751
2. Ron D Translational control in the endoplasmic reticulum stress response J Clin Invest 2002 110 1383 1388
3. Kuwabara K Matsumoto M Ikeda J Hori O Ogawa S Maeda Y et al. Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain J Biol Chem 1996 271 5025 5032
4. Tamatani M Matsuyama T Yamaguchi A Mitsuda N Tsukamoto Y Taniguchi M et al. ORP150 protects against hypoxia/ischemia-induced neuronal death Nat Med 2001 7 317 323
5. Harding HP Ron D Endoplasmic reticulum stress and the development of diabetes Diabetes 2002 51 S455 461
6. Nakatani Y Kaneto H Kawamori D Yoshiuchi K Hatazaki M Matsuoka TA et al. Involvement of endoplasmic reticulum stress in insulin resistance and diabetes J Biol Chem 2005 280 847 851
7. Ozcan U Cao Q Yilmaz E Lee AH Iwakoshi NN Ozdelen E et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes Science 2004 306 457 461
8. Ozawa K Miyazaki M Matsuhisa M Takano K Nakatani Y Ogawa S et al. The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes Diabetes 2005 54 657 663
9. Tsukamoto Y Kuwabara K Hirota S Ikeda J Stern D Yanagi H et al. 150-kD oxygen-regulated protein is expressed in human atherosclerotic plaques and allows mononuclear phagocytes to withstand cellular stress on exposure to hypoxia and modified low density lipoprotein J Clin Invest 1996 98 1930 1941
10. Kobayashi T Yura T Yanagi H The increment of anti-ORP150 autoantibody in initial stages of atheroma in high-fat diet-fed mice Vet Med Sci 2002 64 177 180
11. Yamasaki Y Kawamori R Matsushima H Kajimoto Y Morishima T Kamada T et al. Atherosclerosis in carotid artery of young IDDM patients monitored by ultrasound high-resolution B-mode imaging Diabetes 1994 43 634 639
12. Hayaishi-Okano R Yamasaki Y Katakami N Nishikawa N Kajimoto Y Hori M et al. Elevated C-reactive protein associates with early-stage carotid atherosclerosis in young subjects with type 1 diabetes Diabetes Care 2002 25 1432 1438