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Volumn 34, Issue 2, 2006, Pages 233-244

Homoharringtonine-induced apoptosis of human leukemia HL-60 cells is associated with down-regulation of telomerase

Author keywords

Apoptosis; Homoharringtonine; Leukemia cell; Telomerase

Indexed keywords

DNA; HOMOHARRINGTONINE; TELOMERASE;

EID: 33645059439     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X06003795     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 0033082415 scopus 로고    scopus 로고
    • Cytostatic concentrations of anticancer agents do not affect telomerase activity of leukaemic cells in vitro
    • Akiyama, M., J. Horiguchi-Yamada, S. Saito, Y. Hoshi, O. Yamada, H. Mizoguchi and H. Yamada. Cytostatic concentrations of anticancer agents do not affect telomerase activity of leukaemic cells in vitro. Eur. J. Cancer 35: 309-315, 1999.
    • (1999) Eur. J. Cancer , vol.35 , pp. 309-315
    • Akiyama, M.1    Horiguchi-Yamada, J.2    Saito, S.3    Hoshi, Y.4    Yamada, O.5    Mizoguchi, H.6    Yamada, H.7
  • 2
    • 0003893137 scopus 로고
    • (eds.). Cold Spring Harbor Laboratory Press, New York
    • Blackburn, E. and C. Greider (eds.). Telomeres. Cold Spring Harbor Laboratory Press, New York, 1995.
    • (1995) Telomeres
    • Blackburn, E.1    Greider, C.2
  • 3
    • 0035065901 scopus 로고    scopus 로고
    • Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation
    • Cai, Z., M. Lin, C. Wuchter, V. Ruppert, B. Dörken, W.D. Ludwig and L. Karawajew. Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation. Leukemia 15: 567-574, 2001.
    • (2001) Leukemia , vol.15 , pp. 567-574
    • Cai, Z.1    Lin, M.2    Wuchter, C.3    Ruppert, V.4    Dörken, B.5    Ludwig, W.D.6    Karawajew, L.7
  • 4
    • 4344613440 scopus 로고    scopus 로고
    • Mistletoe lectin induces apoptosis and telomerase inhibition in human A253 cancer cells through dephosphorylation of Akt
    • Choi, S.H., S.Y. Lyu and W.B. Park. Mistletoe lectin induces apoptosis and telomerase inhibition in human A253 cancer cells through dephosphorylation of Akt. Arch Pharm Res. 27: 68-76, 2004.
    • (2004) Arch Pharm Res. , vol.27 , pp. 68-76
    • Choi, S.H.1    Lyu, S.Y.2    Park, W.B.3
  • 5
    • 0020573616 scopus 로고
    • Phase I trial of homoharringtonine administered as a 5-day continuous infusion
    • Coonley, C.J., R.P. Warrell and C.W. Young. Phase I trial of homoharringtonine administered as a 5-day continuous infusion. Cancer Treat Rep. 67: 693-696, 1983.
    • (1983) Cancer Treat Rep. , vol.67 , pp. 693-696
    • Coonley, C.J.1    Warrell, R.P.2    Young, C.W.3
  • 6
    • 0037255947 scopus 로고    scopus 로고
    • Advanced-phase chronic myeloid leukemia
    • Cortes, J. and H. Kantarjian. Advanced-phase chronic myeloid leukemia. Semin. Hematol. 40: 79-86, 2003.
    • (2003) Semin. Hematol. , vol.40 , pp. 79-86
    • Cortes, J.1    Kantarjian, H.2
  • 7
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter, C.M., A.A. Avilion, C.E. Lefeuvre, N.G. Stewart, C.W. Greider, C.B. Harley and S. Bacchetti. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11: 1921-1929, 1992.
    • (1992) EMBO J. , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    Lefeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 8
    • 0033529563 scopus 로고    scopus 로고
    • For better or worse? Telomerase inhibition and cancer
    • de Lange, T. and T. Jacks. For better or worse? Telomerase inhibition and cancer. Cell 98: 273-275, 1999.
    • (1999) Cell , vol.98 , pp. 273-275
    • de Lange, T.1    Jacks, T.2
  • 9
    • 0033973802 scopus 로고    scopus 로고
    • Telomerase activity and telomere length in acute and chronic leukemia, pre- and post-ex vivo culture
    • Engelhardt, M., K. Mackenzie, P. Drullinsky, R.T. Silver and M.A. Moore. Telomerase activity and telomere length in acute and chronic leukemia, pre- and post-ex vivo culture. Cancer Res. 60: 610-617, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 610-617
    • Engelhardt, M.1    Mackenzie, K.2    Drullinsky, P.3    Silver, R.T.4    Moore, M.A.5
  • 10
    • 0033548430 scopus 로고    scopus 로고
    • Anti-apoptotic role of telomerase in pheochromocytoma cells
    • Fu, W., J.G. Begley, M.W. Killen and M.P. Mattson. Anti-apoptotic role of telomerase in pheochromocytoma cells. J. Biol. Chem. 274: 7264-7271, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7264-7271
    • Fu, W.1    Begley, J.G.2    Killen, M.W.3    Mattson, M.P.4
  • 11
    • 0036648449 scopus 로고    scopus 로고
    • Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting telomerase and activation of c-myc and caspases leading to apoptosis
    • Giridharan, P., S.T. Somasundaram, K. Perumal, R.A. Vishwakarma, N.P. Karthikeyan, R. Velmurugan and A. Balakrishnan. Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting telomerase and activation of c-myc and caspases leading to apoptosis. Br. J. Cancer 87: 98-105, 2002.
    • (2002) Br. J. Cancer , vol.87 , pp. 98-105
    • Giridharan, P.1    Somasundaram, S.T.2    Perumal, K.3    Vishwakarma, R.A.4    Karthikeyan, N.P.5    Velmurugan, R.6    Balakrishnan, A.7
  • 12
    • 1542306071 scopus 로고    scopus 로고
    • Telomerase as a growth-promoting factor
    • Gorbunova, V. and A. Seluanov. Telomerase as a growth-promoting factor. Cell Cycle 2: 534-547, 2003.
    • (2003) Cell Cycle , vol.2 , pp. 534-547
    • Gorbunova, V.1    Seluanov, A.2
  • 13
    • 0025279931 scopus 로고
    • Telomeres shorten during aging of human fibroblasts
    • Harley, C.B., A.B. Futcher and C.W. Greider. Telomeres shorten during aging of human fibroblasts. Nature 345: 458-460, 1990.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 15
    • 0032781973 scopus 로고    scopus 로고
    • Resistance to apoptosis in human cells conferred by telomerase function and telomere stability
    • Holt, S.E., V.V. Glinsky, A.B. Ivanova and G.V. Glinsky. Resistance to apoptosis in human cells conferred by telomerase function and telomere stability. Mol. Carcinog. 25: 241-248, 1999a.
    • (1999) Mol. Carcinog. , vol.25 , pp. 241-248
    • Holt, S.E.1    Glinsky, V.V.2    Ivanova, A.B.3    Glinsky, G.V.4
  • 16
    • 0033004686 scopus 로고    scopus 로고
    • Role of telomerase in cellular proliferation and cancer
    • Holt, S.E. and J.W. Shay. Role of telomerase in cellular proliferation and cancer. J. Cell Physiol. 180: 10-18, 1999b.
    • (1999) J. Cell Physiol. , vol.180 , pp. 10-18
    • Holt, S.E.1    Shay, J.W.2
  • 20
    • 0028885644 scopus 로고
    • Interleukin-1 beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells
    • Kondo, S., B.P. Barna, T. Morimura, J. Takeuchi, J. Yuan, A. Akbasak and G.H. Barnett. Interleukin-1 beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells. Cancer Res. 55: 6166-6171, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 6166-6171
    • Kondo, S.1    Barna, B.P.2    Morimura, T.3    Takeuchi, J.4    Yuan, J.5    Akbasak, A.6    Barnett, G.H.7
  • 21
    • 0032580369 scopus 로고    scopus 로고
    • Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosis
    • Kondo, Y., S. Kondo, Y. Tanaka, T. Haqqi, B.P. Barna and J.K. Cowell. Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosis. Oncogene 16: 2243-2248, 1998.
    • (1998) Oncogene , vol.16 , pp. 2243-2248
    • Kondo, Y.1    Kondo, S.2    Tanaka, Y.3    Haqqi, T.4    Barna, B.P.5    Cowell, J.K.6
  • 22
    • 0031006856 scopus 로고    scopus 로고
    • Bcl-2 modulates telomerase activity. J
    • Mandal, M. and R. Kumar. Bcl-2 modulates telomerase activity. J. Biol. Chem. 272: 14183-14187, 1997.
    • (1997) Biol. Chem. , vol.272 , pp. 14183-14187
    • Mandal, M.1    Kumar, R.2
  • 23
    • 0037735274 scopus 로고    scopus 로고
    • Metabolism of homoharringtonine, a cytotoxic component of the evergreen plant Cephalotaxus harringtonia
    • Ni, D., D.H. Ho, M. Vijjeswarapu, E. Felix, P.R. Rhea and Newman R.A. Metabolism of homoharringtonine, a cytotoxic component of the evergreen plant Cephalotaxus harringtonia. J. Exp. Ther. Oncol. 3: 47-52, 2003.
    • (2003) J. Exp. Ther. Oncol. , vol.3 , pp. 47-52
    • Ni, D.1    Ho, D.H.2    Vijjeswarapu, M.3    Felix, E.4    Rhea, P.R.5    Newman, R.A.6
  • 24
    • 0037789547 scopus 로고    scopus 로고
    • Imbalance between apoptosis and telomerase activity in myelodysplastic syndromes: Possible role in ineffective hemopoiesis
    • Ohshima, K., K. Karube, K. Shimazaki, H. Kamma, J. Suzumiya, M. Hamasaki and M. Kikuchi. Imbalance between apoptosis and telomerase activity in myelodysplastic syndromes: Possible role in ineffective hemopoiesis. Leuk. Lymphoma 44: 1339-1346, 2003.
    • (2003) Leuk. Lymphoma , vol.44 , pp. 1339-1346
    • Ohshima, K.1    Karube, K.2    Shimazaki, K.3    Kamma, H.4    Suzumiya, J.5    Hamasaki, M.6    Kikuchi, M.7
  • 26
    • 0031154380 scopus 로고    scopus 로고
    • Cancer researchers validate and pursue telomerase
    • Robertson, D. Cancer researchers validate and pursue telomerase. Nat. Biotechnol. 15: 518, 1997.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 518
    • Robertson, D.1
  • 27
    • 17944401846 scopus 로고    scopus 로고
    • Telomerase is limiting the growth of acute myeloid leukemia cells
    • Roth, A., S. Vercauteren, H.J. Sutherland and P.M. Lansdorp. Telomerase is limiting the growth of acute myeloid leukemia cells. Leukemia 17: 2410-2417, 2003.
    • (2003) Leukemia , vol.17 , pp. 2410-2417
    • Roth, A.1    Vercauteren, S.2    Sutherland, H.J.3    Lansdorp, P.M.4
  • 28
    • 0008789548 scopus 로고    scopus 로고
    • Telomerase activity in acute myelogenous leukaemia: Clinical and biological implications
    • Seol, J.G., E.S. Kim, W.H. Park, C.W. Jung, B.K. Kim and Y.Y. Lee. Telomerase activity in acute myelogenous leukaemia: Clinical and biological implications. Br. J. Haematol. 100: 156-165, 1998.
    • (1998) Br. J. Haematol. , vol.100 , pp. 156-165
    • Seol, J.G.1    Kim, E.S.2    Park, W.H.3    Jung, C.W.4    Kim, B.K.5    Lee, Y.Y.6
  • 29
    • 0027237540 scopus 로고
    • Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumor cells
    • Skladanowski, A. and J. Konopa. Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumor cells. Biochem. Pharmacol. 46: 375-382, 1993.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 375-382
    • Skladanowski, A.1    Konopa, J.2
  • 30
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel, B., A. Smogorzewska and T. de Lange. TRF2 protects human telomeres from end-to-end fusions. Cell 92: 401-413, 1998.
    • (1998) Cell , vol.92 , pp. 401-413
    • van Steensel, B.1    Smogorzewska, A.2    de Lange, T.3


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