Contrasting effects of varicose vein surgery on endothelial-dependent and -independent cutaneous vasodilation in the Perimalleolar Region

European Journal of Vascular and Endovascular Surgery

Volumn 31, Issue 4, 2006, Pages 434-438

  Klonizakis, M ^a   Yeung, J M C ^a,b   Lingam, K ^b   Nash, J R ^b   Manning, G ^a   Donnelly, Richard ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b DERBY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Endothelial function; Laser Doppler; Microvascular; Sodium nitroprusside; Varicose veins

Indexed keywords

ACETYLCHOLINE; NITROPRUSSIDE SODIUM; VASODILATOR AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; ENDOTHELIUM; FEMALE; FEMORAL VEIN; HUMAN; IONTOPHORESIS; LASER DOPPLER FLOWMETRY; MALE; PERFUSION; PRIORITY JOURNAL; SAPHENOUS VEIN; STANDING; STATISTICAL ANALYSIS; STIMULUS RESPONSE; SUPINE POSITION; VARICOSIS; VASODILATATION; VEIN INSUFFICIENCY; VEIN LIGATION; VEIN SURGERY;

ACETYLCHOLINE; ANKLE; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; IONTOPHORESIS; MALE; MIDDLE AGED; NITROPRUSSIDE; POSTURE; SAPHENOUS VEIN; SKIN; VARICOSE VEINS; VASODILATION; VASODILATOR AGENTS; VENOUS INSUFFICIENCY;

EID: 33645031358     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2005.10.017     Document Type: Article

References (17)

1. T.M. Loosemore J.A. Dormandy Pathophysiology of venous ulceration Vasc Med Rev 4 1993 49-57
2. G.J. Murphy S.A. White M.L. Nicholson Vascular access for haemodialysis Br J Surg 87 2000 1300-1315
3. M. Klonizakis J.M.C. Yeung J.R. Nash K. Lingam G. Manning R. Donnelly Effects of posture and venous insufficiency on endothelial-dependent and -independent cutaneous vasodilation in the perimalleolar region Eur J Vasc Endovasc Surg 26 2003 100-104
4. P.L. Tharaux R. Girot A. Kanfer J.C. Dussaule J.P. Gaitz L. Tribout et. al. Cutaneous microvascular blood flow and reactivity in patients with homozygous sickle cell anaemia Eur J Haematol 68 2002 327-331
5. J.R. Barwell M. Taylor J. Deacon A.S. Ghauri C. Wakely L.K. Phillips et. al. Surgical correction of isolated superficial venous reflux reduces long-term recurrence rate in chronic venous leg ulcers Eur J Vasc Endovasc Surg 20 2000 363-368
6. J.P. Noon B.R. Walker M.F. Hand D.J. Webb Studies with iontophoretic administration of drugs to human dermal vessels in vivo: Cholinergic vasodilation is mediated by dilator prostanoids rather than nitric oxide Br J Clin Pharmacol 45 1998 545-550
7. K.R. Davis J. Ponnampalam R. Hayman S. Arulkumaran R. Donnelly Microvascular vasodilator response to acetylcholine is increased in women with pre-eclampsia Br J Obstet Gynaecol 108 2001 610-614
8. W.D. Strain N. Chaturvedi C.J. Bulpitt C. Rajkumar A.C. Shore Albumin excretion rate and cardiovascular risk: Could the association be explained by early microvascular dysfunction? Diabetes 54 2005 1816-1822
9. S.B. Palder R.L. Kirkman A.D. Whittemore R.M. Hakim J.M. Lazarus N.L. Tilney Vascular access for haemodialysis. Patency rates and results of revision Ann Surg 202 1985 235-239
10. R. Bull G. Ansell A.W. Stanton J.R. Levick P.S. Mortimer Normal cutaneous microcirculation in gaiter zone (ulcer-susceptible skin) versus nearby regions in healthy young adults Int J Microcirc Clin Exp 15 1995 65-74
11. U. Kalus J. Koscielny A. Grigorov E. Schaefer H. Peil H. Kiesewetter Improvement of cutaneous microcirculation and oxygen supply in patients with chronic venous insufficiency by orally administered extract of red vine leaves AS195: A randomised, double-blind, placebo-controlled, crossover trial Drugs R D 5 2004 63-71
12. O. Henriksen P. Sejersen Local reflex in microcirculation in human cutaneous tissue Acta Physiol Scand 98 1976 227-231
13. R. Kowalewski K. Sobolewski M. Wolanska M. Gacko Matrix metalloproteinases in the vein wall Int Angiol 23 2004 164-169
14. J. Golledge F.G. Quigley Pathogenesis of varicose veins Eur J Vasc Endovasc Surg 25 2003 319-324
15. P. Zamboni G. Scapoli V. Lanzara M. Izzo P. Fortini R. Legnaro et. al. Serum iron and matrix metalloproteinase-9 variations in limbs affected by chronic venous disease and venous leg ulcers Dermatol Surg 31 2005 644-649
16. D.N. Kolbach K. Hamulyak M.H. Prins H.A. Neumann J.P. Cleutjens Severity of venous insufficiency is related to the density of microvascular deposition of PAI-1, uPA and von Willibrand factor Vasa 33 2004 19-24
17. T. Urbanek B. Skop R. Wiaderkiewicz T. Wilczok K. Ziaja T. Lebda-Wyborny et. al. Smooth muscle cell apoptosis in primary varicose veins Eur J Vasc Endovasc Surg 28 2004 600-611