A rare case of adult-onset nesidioblastosis treated successfully with diazoxide

Endocrine Journal

Volumn 53, Issue 1, 2006, Pages 95-100

  Arao, Tadashi ^a   Okada, Yosuke ^a,b   Hirose, Akiko ^a   Tanaka, Yoshiya ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Adult onset nesidioblastosis; ASVS; Diazoxide; Hypoglycemia

Indexed keywords

DIAZOXIDE; OCTREOTIDE; VOGLIBOSE;

ADULT; ANGIOGRAPHY; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DIET THERAPY; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HOSPITAL ADMISSION; HUMAN; HYPERINSULINEMIA; HYPERTROPHY; HYPOGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULINOMA; LABORATORY TEST; MALE; MEDICAL EXAMINATION; PANCREAS DUCT; PANCREAS ISLET; PANCREAS ISLET BETA CELL; POSTOPERATIVE PERIOD; SPLEEN ARTERY; STIMULATION;

ANGIOGRAPHY; BLOOD GLUCOSE; DIAGNOSIS, DIFFERENTIAL; DIAZOXIDE; HUMANS; HYPERINSULINISM; HYPOGLYCEMIA; INSULIN-SECRETING CELLS; INSULINOMA; LIVER; MALE; MIDDLE AGED; NESIDIOBLASTOSIS; PANCREATIC NEOPLASMS; VASODILATOR AGENTS;

EID: 33644996354     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.53.95     Document Type: Article

References (31)

1. Goudswaard WB, Houthoff HJ, Koudstaal J, Zwierstra RP (1986) Nesidioblastosis and endocrine hyperplasia of the pancreas: a secondary phenomenon. Hum Pathol 17: 46-54.
2. Brown RE, Young RB (1970) A possible role for the exocrine pancreas in the pathogenesis of neonatal leucrine sensitive hypoglycemia. Am J Dig Dis 15: 65-72.
3. Walmsley D, Matheson NA, Ewen S, Himsworth RL, Bevan JS (1995) Nesidioblastosis in an elderly patient. Diabetic Med 12: 542-545.
4. Inagaki N, Gonoi T, Clement JP 4th, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J (1995) Reconstitution of IKATP: an inward rectifier subunit plus the sulfonyurea receptor. Science 270: 1166-1170.
5. + channel. Mol Cell Biol 18: 1652-1659.
6. Bryan J, Aguilar-Bryan L (1997) The ABCs of ATP-sensitive potassium channels: more pieces to the puzzle. Curr Opin Cell Biol 9: 553-559.
7. 2+ increase via suppression of channels in cultured rat adrenal chromaffin cells. J Neurochem 69: 377-387.
8. + current: a potential mechanism of the proarrhythmic effects of methanesulfonanilide class III agents. Cardiovasc Res 43: 125-134.
9. Doppman JL, Chang R, Shawker TH, Gorden P, Norton JA (1991) Insulinomas: localization with selective intra arterial injection of calcium. Ann Intern Med 123: 269-273.
10. Service FJ, Natt N, Thompson GB, Grant CS, van Heerden JA, Andrews JC, Lorenz E, Terzic A, Lloyd RV (1999) Noninsulinoma pancreatogenous hypoglycemia: A novel syndrome of hyperinsulinemic hypoglycemia in adults independent of mutations in Kir6.2 and SUR1 genes. J Clin Endocrinol Metab 84: 1582-1589.
11. Thompson GB, Service FJ, Andrews JC, Lloyd RV, Natt N, van Heerden JA, Grant CS (2000) Noninsulinoma pancreatogenous hypoglycemia syndrome: an update in 10 surgically treated patients. Surgery 128: 937-944.
12. Kaczirek K, Soleiman A, Schindl M, Passler C, Scheuba C, Prager G, Kaserer K, Niederle B (2003) Nesidioblastosis in adults: a challenging cause organic hyperinsulinism. Eur J Clin Invest 33: 488-492.
13. Harrison TS, Fajans SS, Floyd JC Jr, Thompson NW, Rasbach DA, Santen RJ, Cohen C(1984) Prevalence of diffuse pancreatic beta islet cell disease with hyperinsulinism: problems in recognition and management. World J Surg 8: 583-589.
14. Stefanini P, Carboni M, Patrassi N, Basoli A (1974) Hypoglycemia and insular hyperplasia: review of 148 cases. Ann Surg 180: 130-135.
15. Gebhard B, Holst JJ, Biegelmayer B, Miholic J (2001) Postprandial GLP-1, norepinephrine, and reactive hypoglycemia in dumping syndrome. Dig Dis Sci 46: 1915-1923.
16. Brubaker PL, Drucker DJ (2004) Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology 145: 2653-2659.
17. Service GJ, Thompson GB, Service FJ, Andrews JC, Collazo-Clavell ML, Lloyd RV (2005) Hyperinsulinemic hypoglycemia with nesidioblastosis after gastricbypass surgery. N Engl J Med 353: 249-254.
18. Witteles RM, Straus II FH, Sugg S, Koka MR, Costa EA, Kaplan EL (2001) Adult-onset nesidioblastosis causing hypoglycemia: an important clinical entity and continuing treatment dilemma. Arch Surg 136: 656-663.
19. Katai M, Sakurai A, Inaba H, Ikeo Y, Yamauchi K, Hashizume K (2005) Octreotide as a rapid and effective painkiller for metastatic carcinoid tumor. Endocrine J 52: 277-280.
20. Eugster EA, Pescovitz OH (1999) Gigantism. J Clin Endocrinol Metab 84: 4379-4384.
21. Otsuka F, Mizobuchi S, Ogura T, Sato K, Yokoyama M, Makino H(2004) Long-term effects of octreotide on pituitary gigantism: Its analgesic action on cluster headache. Endocrine J 51: 499-452.
22. Lamberts SW, van der Lely AJ, de Herder WW, Hofland LJ (1996) Octreotide. N Engl J Med 334: 246-254.
23. ATP channels learned from Kir6.2 genetically engineered mice. Diabetes 49: 311-318.
24. Aguilar-Bryan L, Bryan J (1999) Molecular biology of adenosine triphosphate-sensitive potassium channels. Endocrine Rev 20: 101-135.
25. Clayton PT, Eaton S, Aynsley-Green A, Edginton M, Hussain K, Krywawych S, Datta V, Malingre HE, Berger R, van den Berg IE (2001) Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of β-oxidation in insulin secretion. J Clin Invest 108: 457-465.
26. Molven A, Matre GE, Duran M, Wanders RJ, Rishaug U, Njolstad PR, Jellum E, Sovik O(2004) Familial hyperinsulinemic hypoglycemia caused by a defect in the SCHAD enzyme of mitochondrial fatty acid oxidation. Diabetes 53: 221-227.
27. Ashcroft FM (2005) ATP-sensitive potassium channelopathies: focus on insulin secretion. J Clin Invest 115: 2047-2058.
28. + channels in mouse pancreatic β-cells. Br J Pharmacol 98: 957-965.
29. Comi RJ, Gorden P, Doppman JL (1993) Insulinoma. In: Go VLW (ed) The Pancreas: Biology, Pathology, and Disease, 2nd ed, Raven Press, New York, 979-996.
30. Arita Y, Ito T (2004) Diagnosis and treatment of insulinoma. Jpn J Gastroenterol 101: 359-366 (in Japanese).
31. Tulassay Z, Tulassay T, Gupta R, Cierny G (1989) Long acting somatostatin analogue in dumping syndrome. Br J Surg 76: 1294-1295.