Aortic arch thrombosis in a neonate with heterozygous carrier status of factor V leiden mutation

Congenital Heart Disease

Volumn 1, Issue 1-2, 2006, Pages 40-45

  Metsvaht, Tuuli ^a   Hermlin, Toomas ^a   Kern, Hartmut ^b   Kahre, Tiina ^a   Starkopf, Joel ^a  

^a TARTU UNIVERSITY CLINICS   (Estonia)

^b German Red Cross Hospital   (Germany)

Author keywords

Aortic arch; Ascending aorta; Newborn; Occlusion; Thrombolysis; Thrombosis

Indexed keywords

AMINOTRANSFERASE; BLOOD CLOTTING FACTOR 5 LEIDEN; DOBUTAMINE; DOPAMINE; FRESH FROZEN PLASMA; LOW MOLECULAR WEIGHT HEPARIN; OXYGEN; PROSTAGLANDIN E2; PROTHROMBIN; STREPTOKINASE; TISSUE PLASMINOGEN ACTIVATOR;

AMINOTRANSFERASE BLOOD LEVEL; AORTA ARCH; AORTA COARCTATION; AORTA THROMBOSIS; ARTICLE; ARTIFICIAL VENTILATION; AUTOPSY; BLEEDING; CARDIOPULMONARY INSUFFICIENCY; CARDIOVASCULAR DISEASE; CASE REPORT; CLINICAL FEATURE; CRYOPRECIPITATE; CYANOSIS; DOPPLER ECHOCARDIOGRAPHY; DRUG INFUSION; ECHOCARDIOGRAPHY; FATALITY; FIBRINOGEN DEFECT; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; INFANT; MALE; MUTATIONAL ANALYSIS; OLIGURIA; OXYGEN THERAPY; PLASMA TRANSFUSION; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE; TREATMENT FAILURE; TREATMENT WITHDRAWAL;

ANGIOGRAPHY; AORTA; AORTA, THORACIC; AORTIC DISEASES; BLOOD COAGULATION DISORDERS, INHERITED; FACTOR V; FATAL OUTCOME; HEMODYNAMICS; HETEROZYGOTE; HUMANS; INFANT, NEWBORN; MALE; POINT MUTATION; RISK FACTORS; THROMBOSIS;

EID: 33644975281     PISSN: 1747079X     EISSN: 17470803     Source Type: Journal    
DOI: 10.1111/j.1747-0803.2006.00007.x     Document Type: Article

References (28)

1. Schmidt B, Andrew M. Neonatal thrombosis: Report of a prospective Canadian and international registry. Pediatrics. 1995; 96: 939-943.
2. Nowak-Gottl U, von Kries R, Gobel U. Neonatal symptomatic thromboembolism in Germany: Two year survey. Arch Dis Child Fetal Neonatal Ed. 1997; 76: 163F-167F.
3. Rees D, Cox M, Clegg JB. World distribution of factor V Leiden. Lancet. 1995; 346: 1133-1134.
4. Ridker PM, Miletich JP, Hennekens CH, Buring JE. Ethnic distribution of factor V Leiden in 4047 men and women. Implications for venous thromboembolism screening. JAMA. 1997; 277: 1305-1307.
5. Hajjar K. Factor V Leiden - an unselfish gene? N Engl J Med. 1994; 33: 1585-1587.
6. Andrew M, Paes B, Milner R, et al. Development of the human coagulation system in the full term infant. Blood. 1987; 70: 165-172.
7. Lanari M, Lazzarotto T, Papa I, et al. Neonatal aortic arch thrombosis as a result of congenital cytomegalovirus infection. Pediatrics. 2001; 108: E114.
8. Ahmadi A, Furste HO, Pringsheim W, et al. Congenital aortic thrombosis with complete obliteration of the aortic arch and the great vessels. Thorac Cardiovasc Surg. 1983; 31: 256-259.
9. McFaul RC, Keane JF, Nowicki ER, Castaneda AR. Aortic thrombosis in the neonate. J Thorac Cardiovasc Surg. 1981; 81: 334-337.
10. Trowitzsch E, Bernsau U, Luhmer I, Merkle W, Kallfelz C. Congenital thrombotic occlusion of the ascending aorta and the aortic arch. Pediatr Cardiol. 1985; 6: 165-169.
11. Scott WA, Snider AR, Dick M 2nd, Heidelberger KP, Bove EL, Peschiera AW. Congenital aortic arch thrombosis diagnosed by echocardiography. Am J Cardiol. 1987; 59: 485-486.
12. Pilosoff W, Schober JG, Muller KD, Schumacher G, Sebening W, Babic R. Complete thrombotic obliteration of the ascending aorta and the aortic arch as a cause of acute heart failure in a newborn. Eur J Pediatr. 1988; 148: 11-14.
13. Hamilton RM Penkoske PA, Byrne P, Duncan NF. Spontaneous aortic thrombosis in a neonate presenting as coarctation. Ann Thorac Surg. 1988; 45: 564-565.
14. Conti VR, Bilfinger TV, Wolf W. Aortic arch thrombosis in the neonate. J Thorac Cardiovasc Surg. 1988; 95: 138-140.
15. Uva MS, Serraf A, Lacour-Gayet F, et al. Aortic arch thrombosis in the neonate. Ann Thorac Surg. 1993; 55: 990-992.
16. Evans DJ, Pizer BL, Moghal NE, Joffe HS. Neonatal aortic arch thrombosis. Arch Dis Child. 1994; 71: F125-F127.
17. Zeevi B, Berant M. Spontaneous aortic arch thrombosis in a neonate. Heart. 1999; 81: 560.
18. Davidson A, Luhmer I, Kallfelz HC. Aortic arch thrombosis in the neonate. J Thorac Cardiovasc Surg. 1989; 97: 152-153.
19. Pohl M, Zimmerhackl LB, Heinen F, Sutor AH, Schneppenheim R, Brandis M. Bilateral renal vein thrombosis and venous sinus thrombosis in a neonate with factor V mutation (FV Leiden). J Pediatr. 1998; 132: 159-161.
20. Hagström JN, Walter J, Bluebond-Langner R, Amatniek JC, Manno CS, High KA. Prevalence of the factor V Leiden mutation in children and neonates with thromboembolic disease. J Pediatr. 1998; 133: 777-781.
21. Aschka I, Aumann V, Bergmann F, et al. Prevalence of factor V Leiden in children with thromboembolism. Eur J Pediatr. 1996; 155: 1009-1014.
22. Nowak-Gottl U, Koch HG, Aschka I, et al. Resistance to activated protein C (APCR) in children with venous or arterial thromboembolism. Br J Haematol. 1996; 92: 992-998.
23. Farnoux C, Camard O, Pinquier D, et al. Recombinant tissue-type plasminogen activator therapy of thrombosis in 16 neonates. J Pediatr. 1998; 133: 137-140.
24. Dizon-Townson D, Meline L, Nelson LM, Varner M, Ward K. Fetal carriers of the factor V Leiden mutation are prone to miscarriage and placental infarction. Am J Obstet Gynecol. 1997; 177: 402-405.
25. Ridker PM, Miletich JP, Buring JE, et al. Factor V Leiden mutation as a risk factor for recurrent pregnancy loss. Ann Intern Med. 1998; 128: 1000-1003.
26. Meinardi JR, Middeldorp S, de Kam PJ, et al. Increased risk for fetal loss in carriers of the factor V Leiden mutation. Ann Intern Med. 1999; 130: 736-739.
27. Kupferminc MJ, Eldor A, Steinman N, et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med. 1999; 340: 9-13.
28. Gopel W, Kim D, Gortner L. Prothrombotic mutations as a risk factor for preterm birth. Lancet. 1999; 353: 1411-1412.