Evaluation of neoplastic human mast cells by tryptase-immunoelectron microscopy

Histopathology

Volumn 48, Issue 3, 2006, Pages 247-257

  Samorapoompichit, P ^a,b   Schernthaner, G H ^b   Worda, C ^b   Wimazal, F ^b   Krauth, M T ^b   Sperr, W R ^b   Valent, P ^b  

^a Medical University of Vienna Institute of Histology and Embryology   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Acute myeloid leukaemia; Neoplastic mast cells; Systemic mastocytosis; Tryptase; Ultrastructure

Indexed keywords

TRYPTASE; SERINE PROTEINASE;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; BLAST CELL; BLOOD CELL; BONE MARROW; CELL GRANULE; CELL MATURATION; CELL NUCLEUS; CELL STRUCTURE; CELL SURFACE; CELL TYPE; CELL ULTRASTRUCTURE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOPLASM; DIAGNOSTIC VALUE; FEMALE; GRANULATION TISSUE; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; LEUKEMIA; MALE; MAST CELL; MAST CELL LEUKEMIA; MYELOMASTOCYTIC LEUKEMIA; PRIORITY JOURNAL; SYSTEMIC MASTOCYTOSIS; TUMOR; UMBILICAL CORD BLOOD; CYTOLOGY; ELECTRON MICROSCOPY; ENZYMOLOGY; FETUS BLOOD; MIDDLE AGED; MYELOID LEUKEMIA; MYELOMONOCYTIC LEUKEMIA; PATHOLOGY; ULTRASTRUCTURE;

ADULT; AGED; CELL NUCLEUS; CYTOPLASM; FEMALE; FETAL BLOOD; HUMANS; LEUKEMIA, MAST-CELL; LEUKEMIA, MYELOID; LEUKEMIA, MYELOMONOCYTIC, ACUTE; MALE; MAST CELLS; MASTOCYTOSIS, SYSTEMIC; MICROSCOPY, ELECTRON; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; SERINE ENDOPEPTIDASES; TRYPTASES;

EID: 33644972948     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2005.02314.x     Document Type: Article

References (40)

1. Lennert K Parwaresch MR Mast cells and mast cell neoplasia: a review Histopathology 1979 3 349 365
2. Metcalfe DD Classification and diagnosis of mastocytosis: current status JInvestDermatol 1991 96 2S 4S
3. Austen KF Systemic mastocytosis NEnglJMed 1992 326 639 640
4. Caplan RM The natural course of urticaria pigmentosa ArchDermatol 1963 87 146 157
5. Valent P Biology, classification and treatment of human mastocytosis Wien KlinWschr 1996 108 385 397
6. Valent P Akin C Sperr WR et al. Diagnosis and treatment of systemic mastocytosis: state of the art BrJHaematol 2003 122 1 23
7. Travis WD Li CY Bergstralh EJ Yam LT Swee RG Systemic mast cell disease. Analysis of 58 cases and literature review Medicine 1988 67 345 368
8. Horny H-P Parwaresch MR Lennert K Bone marrow findings in systemic mastocytosis HumPathol 1985 16 808 814
9. Lawrence JB Friedman BS Travis WD Chinchilli VM Metcalfe DD Gralnick HR Hematologic manifestations of systemic mast cell disease: a prospective study of laboratory and morphologic features and their relation to prognosis AmJMed 1991 91 612 624
10. Travis WD Li CY Yam LT Bergstralh EJ Swee RG Significance of systemic mast cell disease with associated hematologic disorders Cancer 1988 62 965 972
11. Horny H-P Ruck M Wehrmann M Kaiserling E Blood findings in generalized mastocytosis: evidence of frequent simultaneous occurrence of myeloproliferative disorders BrJHaematol 1990 76 186 193
12. Parker RI Hematologic aspects of mastocytosis: II. Management of hematologic disorders in association with systemic mast cell disease JInvestDermatol 1991 96 52S 54S
13. Sperr WR Horny H-P Lechner K Valent P Clinical and biologic diversity of leukemias occurring in patients with mastocytosis Leukemia Lymphoma 2000 37 473 486
14. Travis WD Li CY Hoagland HC Travis LB Banks PM Mast cell leukemia: report of a case and review of literature Mayo ClinProc 1986 61 957 966
15. Dalton R Chan L Batten E Eridani S Mast cell leukaemia: evidence for bone marrow origin of the pathologic clone BrJHaematol 1986 64 397 406
16. Horny H-P Sillaber C Menke D et al. Diagnostic value of immunostaining for tryptase in patients with mastocytosis AmJSurgPathol 1998 22 1132 1140
17. Schwartz LB Metcalfe DD Miller JS Earl H Sullivan T Tryptase levels as an indicator of mast cell activation in systemic anaphylaxis and mastocytosis NEnglJMed 1987 316 1622 1626
18. Schwartz LB Sakai K Bradford TR et al. The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis JClinInvest 1995 96 2702 2710
19. Longley BJ Tyrrell L Lu SZ et al. Somatic c-kit activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm NatGenet 1996 12 312 314
20. Longley BJ Jr. Metcalfe DD Tharp M et al. Activating and dominant inactivating c-kit catalytic domain mutations in distinct forms of human mastocytosis ProcNatl AcadSciUSA 1999 96 1609 1614
21. Escribano L Orfao A Villarrubia J et al. Sequential immunophenotypic analysis of mast cells in a case of systemic mast cell disease evolving to a mast cell leukemia Cytometry 1997 30 98 102
22. Escribano L Orfao A Diaz-Agustin B et al. Indolent systemic mast cell disease in adults: immunophenotypic characterization of bone marrow mast cells and its diagnostic implications Blood 1998 91 2731 2736
23. Valent P Horny H-P Escribano L et al. Diagnostic criteria and classification of mastocytosis: a consensus proposal LeukRes 2001 25 603 625
24. Valent P Horny HP Li CY et al. Pathology and genetics. Tumours of haematopoietic and lymphoid tissues. In Jaffe ES Harris NL Stein H Vardiman JW eds WHO classification of tumours Vol. 1 Geneva World Health Organization 2001 291 302
25. Valent P Sperr WR Samorapoompichit P et al. Myelomastocytic overlap syndromes: biology, criteria, and relationship to mastocytosis LeukRes 2001 25 595 602
26. Sperr WR Escribano L Jordan JH et al. Morphologic properties of neoplastic mast cells: delineation of stages of maturation and implication for cytological grading of mastocytosis LeukRes 2001 25 529 536
27. Agis H Beil WJ Bankl HC et al. Mast cell-lineage versus basophil lineage involvement in myeloproliferative and myelodysplastic syndromes: diagnostic role of cell-immunophenotyping LeukLymphoma 1996 22 187 204
28. Baghestanian M Bankl HC Sillaber C et al. A case of malignant mastocytosis with circulating mast cell precursors: biologic and phenotypic characterization of the malignant clone Leukemia 1996 10 159 166
29. Horny HP Valent P Diagnosis of mastocytosis: general histopathological aspects, morphological criteria, and immunohistochemical findings LeukRes 2001 25 543 551
30. Horny HP Valent P Histopathological and immunohistochemical aspects of mastocytosis IntArchAllergy Immunol 2002 127 115 117
31. Bennett JM Catovsky D Daniel MT et al. Proposals for the classification of the myelodysplastic syndromes BrJHaematol 1982 51 189 199
32. Bennett JM Catovsky D Daniel MT et al. Proposed revised criteria for the classification of acute myeloid leukemia: a report of the French-American British Cooperative Group AnnInternMed 1985 103 620 625
33. Bennett JM Catovsky D Daniel MT et al. The chronic myeloid leukaemias: guidelines for distinguishing chronic granulocytic, atypical chronic myeloid, and chronic myelomonocytic leukaemia BrJHaematol 1994 87 746 754
34. Valent P Spanblöchl E Sperr WR et al. Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture Blood 1992 80 2237 2245
35. -, colony forming cell JImmunol 1993 151 4221 4227
36. Butterfield JH Weiler D Dewald G Gleich GJ Establishment of an immature mast cell line from a patient with mast cell leukemia LeukRes 1988 12 345 355
37. Samorapoompichit P Kiener HP Schernthaner GH et al. Detection of tryptase in cytoplasmic granules of basophils in patients with chronic myeloid leukemia and other myeloid neoplasms Blood 2001 98 2580 2583
38. Valent P Spanblöchl E Bankl HC et al. Kit ligand/mast cell growth factor-independent differentiation of mast cells in myelodysplasia and chronic myeloid leukemia blast crisis Blood 1994 84 4322 4332
39. Valent P Samorapoompichit P Sperr WR Horny HP Lechner K Myelomastocytic leukemia: myeloid neoplasm characterized by partial differentiation of mast cell-lineage cells HematolJ 2002 3 90 94
40. Fukuda T Kamishima T Tsuura Y et al. Expression of the c-kit gene product in normal and neoplastic mast cells but not in neoplastic basophil/mast cell precursors from chronic myelogenous leukaemia JPathol 1995 177 139 146