Syntheses of glucose analogues of E5564 as a highly potent anti-sepsis drug candidate

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 9, 2006, Pages 3011-3016

  Shiozaki, Masao ^a   Doi, Hiromi ^b   Tanaka, Daisuke ^b   Shimozato, Takaichi ^b   Kurakata, Shin Ichi ^b  

^a Chemtech Labo Inc   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

E5564; LPS antagonist; RsDPLA

Indexed keywords

ANTIINFECTIVE AGENT; ERITORAN; GALACTOSAMINE; GLUCOSE DERIVATIVE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; IC 50; IN VIVO STUDY; MOUSE; NONHUMAN;

ANIMALS; ESCHERICHIA COLI; GLUCOSE; LIPID A; MALE; MICE; MOLECULAR STRUCTURE; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 33644968315     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.12.018     Document Type: Article

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