Calculation of high-LET radiotherapy dose required for compensation of overall treatment time extensions

British Journal of Radiology

Volumn 79, Issue 939, 2006, Pages 254-257

  Jones, B ^a   Carabe Fernandez, A ^b   Dale, R G ^b  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER RADIOTHERAPY; CONTROLLED STUDY; DOSE CALCULATION; DOSE TIME EFFECT RELATION; ENERGY METABOLISM; HUMAN; HUMAN TISSUE; LINEAR ENERGY TRANSFER; MATHEMATICAL COMPUTING; METHODOLOGY; RADIATION DOSE; RADIATION RESPONSE; RADIOSENSITIVITY;

ALGORITHMS; HUMANS; LINEAR ENERGY TRANSFER; NEOPLASMS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, HIGH-ENERGY; RELATIVE BIOLOGICAL EFFECTIVENESS; TIME FACTORS;

EID: 33644961539     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr/49977661     Document Type: Article

References (11)

1. Barendsen GW. Dose fractionation, dose rate and iso-effect relationships for normal tissue responses. Int J Radiat Oncol Biol Phys 1982;8:1981-97.
2. Fowler JF. The linear quadratic formula and progress in fractionated radiotherapy. Br J Radiol 1989;62:679-94.
3. Jones B, Dale RG, Deehan C, Hopkins KI, Morgan DAL. The role of biologically effective dose (BED) in clinical oncology. Clin Oncol 2001;13:71-81.
4. Dale RG, Hendry JH, Jones B, Deehan C, Sinclair J, Robertson G. Practical methods for compensating for missed treatment days in radiotherapy, with particular reference to head & neck schedules. Clin Oncol 2002;14:382-93.
5. Dale RG, Jones B, Sinclair JA. Dose equivalents of tumour repopulation during radiotherapy: the potential for confusion. Br J Radiol 2000;73:892-4.
6. Bewley DK. The physics and radiobiology of fast neutron beams. Bristol & New York: Adam Hilger, 1989:113.
7. Kellerer AM, Rossi HH. RBE and the primary mechanism of radiation action. Radiat Res 1971;47:15-34.
8. Tsujii H, Mizoe J, Kamada T, Baba M, Kato S, Kato H, et al. Overview of clinical experiences on carbon ion radiotherapy at NIRS. Radiother Oncol 2004;73 (Suppl. 2):S41-9.
9. Paginetti H, Niemierko A, Ancukiewicz M, Gerweck LE, Goitein M, Loeffler JS, et al. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys 2002;53:407-21.
10. Jones B, Dale RG. Estimation of optimum dose per fraction for high LET radiations: implications for proton radiotherapy. Int J Radiat Oncol Biol Phys 2000;48:1549-57.
11. Schulz-Ertner D, Nikoghosyan A, Thilmann C, Haberer T, Jakel O, Karger C, et al. Results of carbon ion radiotherapy in 152 patients. Int J Radiat Oncol Biol Phys 2004;58:631-40.