Age-related alterations in GABAA receptor subunits in the nonhuman primate hippocampus

Brain Research

Volumn 1073-1074, Issue 1, 2006, Pages 120-130

  Rissman, Robert A ^a,b,d   Nocera, Romy ^b   Fuller, Laura M ^b   Kordower, Jeffrey H ^c   Armstrong, David M ^b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

^d SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Aging; Benzodiazepine; Densitometry; GABA receptor subunit; Hippocampus; Immunohistochemistry; Nonhuman primate

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; RECEPTOR SUBUNIT;

AGED; ALPHA CHAIN; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BETA CHAIN; BRAIN REGION; CONTROLLED STUDY; CYTOLOGY; DENSITOMETRY; DENTATE GYRUS; FEMALE; GENE MUTATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STUDY; RHESUS MONKEY;

AGING; ANALYSIS OF VARIANCE; ANIMALS; DENSITOMETRY; FEMALE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MACACA MULATTA; MALE; PROTEIN SUBUNITS; RECEPTORS, GABA-A;

ANIMALIA; MACACA MULATTA; PRIMATES;

EID: 33644953455     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.12.036     Document Type: Article

References (54)

1. D.G. Amaral, and R. Insausti The hippocampal formation G. Paxinos The Human Nervous System 1990 Academic Press Boston 711 754
2. M. Banay-Schwartz, A. Lajtha, and M. Palkovitis Changes with aging in the levels of the amino acids in rat CNS structural elements: I. Glutamate and related amino acids Neurochem. Res. 14 1989 555 562
3. E.A. Barnard, P. Skolnick, R.W. Olsen, H. Mohler, W. Siegart, G. Biggio, C. Braestrup, A.N. Bateson, and S.Z. Langer International Union of Pharmacology: XV. Subtypes of GABAA receptor: classification on the basis of subunit structure and receptor function Pharmacol. Rev. 50 1998 291 331
4. T.P. Bonnert, R.M. McKernan, S. Farrar, B. Le Bourdelles, R.P. Heavens, L. Hewson, M.R. Rigby, D.J. Sirnathsinghji, N. Brown, K.A. Wafford, and P.J. Whitting θ, a novel γ-aminobutyric acid type a receptor subunit Proc. Natl. Acad. Sci. U. S. A. 96 1999 9891 9896
5. - flux in rat brain membrane vesicles Life Sci. 43 1988 1761 1771
6. H.M. Duvernoy The human hippocampus Atlas of Applied Anatomy 1988 Gergmann Verlag München, F.R.G 43 75
7. M. Ewert, B.D. Shivers, H. Luddens, H. Mohler, and P.H. Seeburg Subunit specificity and epitope characterization of monoclonal antibodies directed against the GABAA/benzodiazepine receptor J. Cell Biol. 110 1990 2043 2048
8. A receptor-coupled chloride ionophore in rat cerebral cortex J. Neurochem. 53 1989 648 651
9. M. Esclapez, J.C. Hirsch, R. Khazipov, Y. Ben-Ari, and C. Bernard Opertative GABAergic inhibition in hippocampal ca1 pyramidal neurons in experimental epilepsy Proc. Natl. Acad. Sci. U. S. A. 94 22 1997 12151 12156
10. R. Garcia, and R. Jafford A comparative study of age-related changes in inhibitory processes and long-term potentiation in the lateral septum of mice Brain Res. 620 1983 229 236
11. W.H. Griffith, and D.A. Murchison Enhancement of GABA-activated membrane currents in aged Fisher 344 rat basal forebrain neurons J. Neurosci. 15 1995 2407 2416
12. A receptor subunits and glutamic acid decarboxylase in the rat inferior colliculus J. Neurosci. 14 1994 7469 7477
13. A receptor in the rat hippocampus Neuroscience 74 1996 341 348
14. A receptors in the human hippocampal formation J. Neurosci. 8 1988 1370 1383
15. A receptor subtypes in developing hippocampal neurons Neuron 7 1991 927 933
16. J.L. Kominsky Aging: effect of ex-vivo benzodiazepine binding after a diazepam injection Neurochem. Res. 12 1987 745 749
17. J.L. Kominsky, and M.F. MacFarland Aging: effect on neuronal and non-neuronal benzodiazepine binding sites Neurochem. Res. 8 1983 1135 1141
18. A receptor subunit mRNAs in the rat brain: II. Olifactory bulb and cerebellum J. Neurosci. 12 1992 1063 1076
19. A receptor subunit mRNAs in the rat brain: III. Embryonic and postnatal development J. Neurosci. 12 1992 4151 4172
20. A receptor channels Trends Pharmacol. Sci. 3 1991 219 230
21. A receptor channels Annu. Rev. Neurosci. 17 1994 569 602
22. B.R. Meyer Benzodiazepines in the elderly Med. Clin. N. Am. 66 5 1992 1017 1035
23. A receptor subunit mRNA levels in Fischer rats Mol. Brain Res. 14 1992 71 78
24. A/benzodiazepine receptors Mol. Brain Res. 24 1994 71 78
25. A receptor beta2/3 in the hippocampal formation of aged brains with Alzheimer-related neuropathologic changes Exp. Neurol. 147 1997 333 345
26. A receptor γ1 subunit in the hippocampal formation of aged brains with Alzheimer-related neuropathologic changes Brain Res. 799 1998 148 155
27. A receptor beta 2 and beta 3 subunits mRNA in the hippocampal formation of aged human brain with Alzheimer-related neuropathology Mol. Brain Res. 56 1-2 1998 268 272
28. A receptors. From subunits to diverse functions Ion Channels 4 1996 89 113
29. M. Monane Insomnia in the elderly J. Clin. Psychiatry 53 1992 23 28 (Suppl.)
30. J. Nissanov, and D.L. McEachron Advances in image processing for autoradiograph J. Chem. Neuroanat. 4 1991 329 342
31. J. Nissanov, S. Mani, and O.J. Tretiak Automatic grain counting Abstr.-Soc. Neurosci. 17 1991 590.8
32. A receptors FASEB J. 1990 1469 1480
33. Paul GABA and glycine F.E. Bloom D.J. Kupfer Psychopharmacology: The Fourth Generation of Progress 1995 Raven Press Ltd. New York 87 94
34. N.W. Pedigo, H. Schoemaker, M. Morelli, J.N. McDougal, J.B. Malick, T.F. Bucks, and H.I. Yamamura Benzodiazepine receptor binding in young, mature, and senescent rat brain and kidney Neurobiol. Aging 2 1981 83 88
35. A receptor subunits in the rat CNS J. Comp. Neurol. 326 1992 193 216
36. A. Peters, D.L. Rosene, M.B. Moss, T.L. Kemper, C.R. Abraham, J. Tigges, and M.S. Albert Neurobiological bases of age-related cognitive decline in the rhesus monkey J. Neuropathol. Exp. Neurol. 55 8 1996 861 874
37. D.L. Pettit, and G.J. Augustine Distribution of functional glutamate and GABA receptors on hippocampal pyramidal cells and interneurons J. Neurophysiol. 84 1 2000 28 38
38. A benzodiazepine receptors produced in transfected cells Science 242 1988 1389 1392
39. A receptor research Synapse 21 1995 189 274
40. P.M. Reeves, and M.P. Schweizer Aging, diazepam exposure and benzodiazepine receptors in the rat cortex Brain Res. 270 1983 376 379
41. A/benzodiazepine in the rat hippocampus during aging J. Pharmacol. Exp. Ther. 256 1991 902 908
42. A/benzodiazepine receptor complex Eur. J. Pharmacol. 267 1994 123 128
43. A receptor complex from rat cerebral cortex and hippocampus J. Neurochem. 64 1994 867 873
44. D.J. Ruano, J. Benavides, A. Machado, and J. Vitoria Aging-associated changes in the pharmacological properties of the benzodiazepine (ω) receptor isotypes in the rat hippocampus Mol. Brain Res. 25 1995 225 233
45. A and alpha-amino-3-hydroxy-5-methylsoxazole-4-propionate receptors are differentially affected by aging in the rat hippocampus J. Biol. Chem. 275 2000 19585 19593
46. A receptors in the brain shown by monoclonal antibodies Nature 314 1985 168 171
47. A receptors in neocortex Mol. Brain Res. 14 1992 207 212
48. W. Sieghart Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes Pharmacol. Rev. 47 1995 181 234
49. J. Tigges, J.G. Herndon, and D.L. Rosene Mild age-related changes in the dentate gyrus of adult rhesus monkeys Acta Anat. (Basel) 153 1 1995 39 48
50. C.C. Tsang, K.V. Speeg, and G.R. Wilkinson Aging and benzodiazepine binding in the rat cerebral cortex Life Sci. 30 1982 343 346
51. S.L. Vincent, A. Peters, and J. Tigges Effects of aging on the neurons within area 17 of rhesus monkey cerebral cortex Anat. Rec. 223 3 1989 329 341
52. A receptor gene family Ann. N. Y. Acad. Sci. 868 1999 645 653
53. A receptor subunit mRNA in the rat brain: I. Telencephalon, diencephalon, mesencephalon J. Neurosci. 12 1992 1041 1062
54. A binding in the brains of aged rats and monkeys Neurobiol. Aging 12 1991 93 98