Chemoselective hydrazone formation between HYNIC-functionalized peptides and 18F-fluorinated aldehydes

Nuclear Medicine and Biology

Volumn 33, Issue 2, 2006, Pages 173-183

  Bruus Jensen, Kjerstin ^a   Poethko, Thorsten ^a   Schottelius, Margret ^a   Hauser, Andrea ^a   Schwaiger, Markus ^a   Wester, Hans Jürgen ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

18F; Chemoselective; Hydrazone formation; Peptide; PET; Radiohalogenation

Indexed keywords

4 FLUOROBENZALDEHYDE F 18; 4 FORMYL N,N,N TRIMETHYLANILINIUM TRIFLATE; 6 HYDRAZINONICOTINIC ACID; ALDEHYDE DERIVATIVE; ANILINE DERIVATIVE; DIMETHYL SULFOXIDE; FLUORINE 18; FLUORINE DERIVATIVE; HYDRAZONE DERIVATIVE; NICOTINIC ACID DERIVATIVE; OCTREOTIDE; PEPTIDE DERIVATIVE; SUBSTANCE P DERIVATIVE; TECHNETIUM 99M; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DEGRADATION; DRUG STABILITY; FEMALE; FLUORINATION; ISOTOPE LABELING; MOUSE; MOUSE STRAIN; NONHUMAN; PH; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ALDEHYDES; ANIMALS; FLUORINE RADIOISOTOPES; HYDRAZINES; HYDRAZONES; ISOTOPE LABELING; METABOLIC CLEARANCE RATE; MICE; NICOTINIC ACIDS; PEPTIDES; RADIOPHARMACEUTICALS;

EID: 33644938767     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2005.10.010     Document Type: Article

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