The cannabinoid CB1 receptor mediates retrograde signals for depolarization-induced suppression of inhibition in cerebellar Purkinje cells

Journal of Neuroscience

Volumn 22, Issue 5, 2002, Pages 1690-1697

  Yoshida, Takayuki ^a   Hashimoto, Kouichi ^a   Zimmer, Andreas ^b   Maejima, Takashi ^a   Araishi, Kenji ^a   Kano, Masanobu ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Cannabinoid receptor; Cerebellum; Inhibitory transmission; Purkinje cell; Retrograde signal; Synaptic modulation

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; CALCIUM ION; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR AGONIST; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; METABOTROPIC RECEPTOR; RIMONABANT; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CALCIUM CELL LEVEL; CEREBELLUM; CONTROLLED STUDY; DEPOLARIZATION; HIPPOCAMPUS; KNOCKOUT MOUSE; MOUSE; NERVE ENDING; NERVE FIBER; NONHUMAN; POSTSYNAPTIC INHIBITION; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PURKINJE CELL; RECEPTOR BLOCKING; RECEPTOR OCCUPANCY; RETROGRADE NERVE FIBER TRANSPORT;

EID: 0036523103     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-05-01690.2002     Document Type: Article

References (37)

1. Batchelor AM, Garthwaite J (1997) Frequency detection and temporally-dispersed synaptic signal association through a metabotropic glutamate receptor pathway. Nature 385:74-77.
2. Bisogno T, Sepe N, Melck D, Maurelli S, De-Petrocellis L, Di Marzo V (1997) Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylgrycerol in mouse neuroblastome cells. Biochem J 322:671-677.
3. Di Marzo V, Fontana A, Cadas H, Schinelli S, Cimino G, Schwartz J-C, Piomelli D (1994) Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature 372:686-691.
4. Egertova M, Elphick MR (2000) Localisation of cannabinoid receptors in the rat brain using antibodies to the intracellular C-terminal tail of CB1. J Comp Neurol 422:159-171.
5. Eilers J, Callewaert G, Armstrong CM, Konnerth A (1995) Calcium signaling in a narrow somatic submembrane shell during synaptic activity in cerebellar Purkinje neurons. Proc Natl Acad Sci USA 92:10272-10276.
6. Finch EA, Augustine GJ (1998) Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites. Nature 396:753-756.
7. Glitsch M, Jack JJB (2001) Evidence that glutamate acting on presynaptic type-II metabotropic glutamate receptors alone does not fully account for the phenomenon of depolarization-induced suppression of inhibition in cerebellar Purkinje cells. Pflügers Arch 442:404-408.
8. Glitsch M, Llano I, Marty A (1996) Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum. J Physiol (Lond) 497:531-537.
9. 2+. Eur J Neurosci 12:987-993.
10. Herkenham M, Lynn AB, Little MD, Johnson MR, Melvin LS, De Costa BR, Rice KC (1990) Cannabinoid receptor localization in brain. Proc Natl Acad Sci USA 87:1932-1936.
11. Herkenham M, Lynn AB, Johnson MR, Melvin LS, de Costa BR, Rice KC (1991) Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study. J Neurosci 11:563-583.
12. A synaptic transmission in the hippocampus. J Neurosci 20:2470-2479.
13. Kano M, Rexhausen U, Dreessen J, Konnerth A (1992) Synaptic excitation produces a long-lasting rebound potentiation of inhibitory synaptic currents in cerebellar Purkinje cells. Nature 356:601-604.
14. Kano M, Hashimoto K, Chen C, Abeliovich A, Aiba A, Kurihara H, Watanabe M, Inoue Y, Tonegawa S (1995) Impaired synapse elimination during cerebellar development in PKCγ mutant mice. Cell 83:1223-1231.
15. Kano M, Hashimoto K, Kurihara H, Watanabe M, Inoue Y, Aiba A, Tonegawa S (1997) Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1. Neuron 18:71-79.
16. Kreitzer AC, Regehr WG (2001a) Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron 29:717-727.
17. Kreitzer AC, Regehr WG (2001b) Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids. J Neurosci 21:RC174.
18. Llano I, Leresche N, Marty A (1991) Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents. Neuron 6:565-574.
19. Mackie K, Hille B (1992) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci USA 89:3825-3829.
20. Maejima T, Ohno-Shosaku T, Kano M (2001a) Endogenous cannabinoid as a retrograde messenger from depolarized postsynaptic neurons to presynaptic terminals. Neurosci Res 40:205-210.
21. Maejima T, Hashimoto K, Yoshida T, Aiba A, Kano M (2001b) Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron 31:463-475.
22. Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990) Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564.
23. Matsuda LA, Bonner TI, Lolait SJ (1993) Localization of cannabinoid receptor mRNA in rat brain. J Comp Neurol 327:535-550.
24. Montgomery J, Madison DV (2001) The grass roots of synapse suppression. Neuron 29:567-570.
25. Morishita W, Kirov SA, Alger BE (1998) Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1. J Neurosci 18:4870-4882.
26. Munro S, Thomas KL, Abu-Shaar M (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365:61-65.
27. Ohno-Shosaku T, Sawada S, Yamamoto C (1998) Properties of depolarization-induced suppression of inhibitory transmission in cultured rat hippocampal neurons. Pflügers Arch 435:273-279.
28. Ohno-Shosaku T, Maejima T, Kano M (2001) Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals. Neuron 29:729-738.
29. A responses in hippocampal pyramidal cells. J Neurosci 12:4122-4132.
30. Stella N, Schweitzer P, Piomelli D (1997) A second endogenous cannabinoid that modulates long-term potentiation. Nature 388:773-778.
31. Takahashi KA, Linden DJ (2000) Cannabinoid receptor modulation of synapses received by cerebellar Purkinje cells. J Neurophysiol 83:1167-1180.
32. Takechi H, Eilers J, Konnerth A (1998) A new class of synaptic response involving calcium release in dendritic spines. Nature 396:757-760.
33. Twitchell W, Brown S, Mackie K (1997) Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. J Neurophysiol 78:43-50.
34. Vincent P, Armstrong CM, Marty A (1992) Inhibitory synaptic currents in rat cerebellar Purkinje cells: Modulation by postsynaptic depolarization. J Physiol (Lond) 456:453-471.
35. Wilson RI, Nicoll RA (2001) Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses. Nature 410:588-592.
36. Wilson RI, Kunos G, Nicoll RA (2001) Presynaptic specificity of endocannabinoid signaling in the hippocampus. Neuron 31:453-462.
37. Zimmer A, Zimmer AM, Hohmann AG, Herkenham M, Bonner TM (1999) Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci USA 96:5780-5785.