Expression of extracellular matrix protein 1 (ECM1) in human skin is decreased by age and increased upon ultraviolet exposure

British Journal of Dermatology

Volumn 154, Issue 2, 2006, Pages 218-224

  Sander, C S ^a   Sercu, S ^b   Ziemer, M ^a   Hipler, U C ^a   Elsner, P ^a   Thiele, J ^c   Merregaert, J ^b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Extracellular matrix protein 1; Lichen sclerosus; Lipoid proteinosis; Photoageing; Skin ageing; Ultraviolet exposure

Indexed keywords

EXTRACELLULAR MATRIX PROTEIN 1; ISOPROTEIN; POLYCLONAL ANTIBODY; RABBIT ANTISERUM; SCLEROPROTEIN; UNCLASSIFIED DRUG;

AGE DISTRIBUTION; AGED; ARTICLE; BASAL CELL; BLOOD VESSEL; BUTTOCK; CLINICAL ARTICLE; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DENSITOMETRY; DERMIS; DIAGNOSTIC PROCEDURE; ELASTOSIS; EPIDERMIS CELL; FOLLOW UP; HAIR FOLLICLE; HEALTH STATUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; PHOTOAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RADIATION EXPOSURE; RADIATION PROTECTION; REGULATORY MECHANISM; SIMULATOR; SKIN BIOPSY; STAINING; SWEAT GLAND; ULTRAVIOLET IRRADIATION;

ADULT; AGED; EPIDERMIS; EXTRACELLULAR MATRIX PROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; MIDDLE AGED; RADIATION INJURIES; SKIN; SKIN AGING; ULTRAVIOLET RAYS; UP-REGULATION;

EID: 33644928436     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2005.07001.x     Document Type: Article

References (27)

1. Smits P Ni J Feng P et al. The human extracellular matrix gene 1 (ECM1): genomic structure, cDNA cloning, expression pattern, and chromosomal localization Genomics 1997 45 487 95
2. Johnson MR Wilkin DJ Vos HL et al. Characterization of the human extracellular matrix protein 1 gene on chromosome 1q21 Matrix Biol 1997 16 289 92
3. Mongiat M Fu J Oldershaw R et al. Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis J Biol Chem 2003 278 17491 9
4. Deckers MM Smits P Karperien M et al. Recombinant human extracellular matrix protein 1 inhibits alkaline phosphatase activity and mineralization of mouse embryonic metatarsals in vitro Bone 2001 28 14 20
5. Han Z Ni J Smits P et al. Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells FASEB J 2001 15 988 94
6. Chan I The role of extracellular matrix protein 1 in human skin Clin Exp Dermatol 2004 29 52 6
7. Hamada T McLean WH Ramsay M et al. Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1) Hum Mol Genet 2002 11 833 40
8. Hamada T Wessagowit V South AP et al. Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation J Invest Dermatol 2003 120 345 50
9. Oyama N Chan I Neill SM et al. Autoantibodies to extracellular matrix protein 1 in lichen sclerosus Lancet 2003 362 118 23
10. Oyama N Chan I Neill SM et al. Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus J Clin Invest 2004 113 1550 9
11. van Hougenhouck-Tulleken W Chan I Hamada T et al. Clinical and molecular characterization of lipoid proteinosis in Namaqualand, South Africa Br J Dermatol 2004 151 413 23
12. Smits P Poumay Y Karperien M et al. Differentiation-dependent alternative splicing and expression of the extracellular matrix protein 1 gene in human keratinocytes J Invest Dermatol 2000 114 718 24
13. Hamada T Lipoid proteinosis Clin Exp Dermatol 2002 27 624 9
14. Powell JJ Wojnarowska F Lichen sclerosus Lancet 1999 353 1777 83
15. Sander CS Ali I Dean D et al. Oxidative stress is implicated in the pathogenesis of lichen sclerosus Br J Dermatol 2004 151 627 35
16. Varani J Spearman D Perone P et al. Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro Am J Pathol 2001 158 931 42
17. Bizot-Foulon V Bouchard B Hornebeck W et al. Uncoordinate expressions of type I and III collagens, collagenase and tissue inhibitor of matrix metalloproteinase 1 along in vitro proliferative life span of human skin fibroblasts. Regulation by all-trans retinoic acid Cell Biol Int 1995 19 129 35
18. Sander CS Chang H Salzmann S et al. Photoaging is associated with protein oxidation in human skin in vivo J Invest Dermatol 2002 118 618 25
19. Grune T Reinheckel T Davies KJ Degradation of oxidized proteins in mammalian cells FASEB J 1997 11 526 34
20. Rittie L Fisher GJ UV-light-induced signal cascades and skin aging Ageing Res Rev 2002 1 705 20
21. Lavker RM Gerberick GF Veres D et al. Cumulative effects from repeated exposures to suberythemal doses of UVB and UVA in human skin J Am Acad Dermatol 1995 32 53 62
22. Jeanmaire C Danoux L Pauly G Glycation during human dermal intrinsic and actinic ageing: an in vivo and in vitro model study Br J Dermatol 2001 145 10 18
23. Tanaka N Tajima S Ishibashi A et al. Immunohistochemical detection of lipid peroxidation products, protein-bound acrolein and 4-hydroxynonenal protein adducts, in actinic elastosis of photodamaged skin Arch Dermatol Res 2001 293 363 7
24. Smits P Bhalerao J Merregaert J Molecular cloning and characterization of the mouse Ecm1 gene and its 5′ regulatory sequences Gene 1999 226 253 61
25. Fisher GJ Kang S Varani J et al. Mechanisms of photoaging and chronological skin aging Arch Dermatol 2002 138 1462 70
26. Peus D Pittelkow MR Reactive oxygen species as mediators of UVB-induced mitogen-activated protein kinase activation in keratinocytes Curr Probl Dermatol 2001 29 114 27
27. Chung JH Kang S Varani J et al. Decreased extracellular-signal-regulated kinase and increased stress-activated MAP kinase activities in aged human skin in vivo J Invest Dermatol 2000 115 177 82