Improvement of sexual function in partial testosterone-deficient ageing men treated with cream containing testosterone and vasoactive agents

Journal of Men's Health and Gender

Volumn 3, Issue 1, 2006, Pages 47-55

  Gomaa, Adel A ^a   Hamed, Hamed A ^b  

^a Assiut University Faculty of Medicine   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Combination therapy; Cream; Erection; Trial

Indexed keywords

DIHYDROERGOTOXINE; ISOSORBIDE DINITRATE; TESTOSTERONE; VASOACTIVE AGENT;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DOUBLE BLIND PROCEDURE; DRUG RESPONSE; ERECTILE DYSFUNCTION; GERIATRIC CARE; HORMONE DEFICIENCY; HUMAN; LIBIDO; MAJOR CLINICAL STUDY; MALE; MEN'S HEALTH; PENIS ERECTION; PRIORITY JOURNAL; QUESTIONNAIRE; SEXUAL FUNCTION; SEXUAL INTERCOURSE; TREATMENT OUTCOME;

EID: 33644916647     PISSN: 15718913     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmhg.2004.12.013     Document Type: Article

References (34)

1. P. Arduca Erectile dysfunction. A guide to diagnosis and management Aust Fam Physician 32 2003 414 418
2. M. Kwan, W.J. Greenleaf, J. Mann, L. Crapo, and J.M. Davidson The nature of androgen action on male sexuality: a combined laboratory self-report study on hypogonadel men J Clin Endocr Metab 57 1983 557 560
3. M. Monga, M. Kostelec, and M. Kamarei Patient satisfaction with testosterone supplementation for the treatment of erectile dysfunction Arch Androl 48 2002 433 442
4. S. Arver, A.S. Dobs, A.W. Meikle, R.P. Allen, S.W. Sanders, and N.A. Mazer Improvement of sexual function testosterone deficient men treated for 1 year with a permeation enhanced testosterone transdermal system J Urol 155 1996 1604 1608
5. C. Wang, N. Berman, and J.A. Longstreth pharmacokinetics of transdermal testosterone gel in hypogonadal men: application of gel at one site υ four sites J Clin Endocrinol Metab 85 2000 964 969
6. C. Wang, R. Swerdlof, and A. Iranmanesh Transdermal testosterone gel improves sexual function, mood, Muscle strength, and body composition parameters in hypogonadal men J Clin Endocrinol Metab 85 2000 2839 2853
7. C. Carani, D. Zini, A. Balodini, L. Della Casa, A. Ghizzani, and P. Marrama Efect of androgen treatment in impotent men with normal and low Levels of free testosterone Arch Sex Behav 19 1990 223 225
8. H.A. Feldman, I. Goldstein, D.G. Hatzichristou, R.J. Krae, and J.B. Mckinlay Impotence and its medical and psychosocial correlates: Results of the Massachusetts male aging study J Urol 151 1994 56 61
9. E. Bischoff, M. Schramm, A. Straub, A. Feurer, and J.P. Stasch BAY 41-2272:a stimulator of soluble guanylyl cyclase inducing nitric oxide-dependent penile erection in vivo Urology 61 2003 464 467
10. A. Calabro, Ragazze, N. Realdon, E. Ragazzi, and F. Pagano New topical formulation of isosorbide dinitrate in the treatment of male impotence Pharm Sc 1 1995 499 500
11. M.D. Blum, R.R. Bahnson, T.N. Porter, and M.F. Carter Effect of local alpha adrenergic blockade on human penile erection J urol 134 1985 479 481
12. C. Carani, A.R. Granata, M.F. Fustini, and P. Marrama Prolactin and testosterone: their role in male sexual function In J Androl 19 1996 48 54
13. G. Cavallini minoxidil verus nitroglycerin: A prospective double- blind controlled trial in transcutaneous erection facilitation for organic impotence J urol 146 1991 50 53
14. A. Morales, B. Johnston, J.P.W. Heaton, and M. Lundie Testosterone supplementation for hypogonadal impotence: Assessment of biochemical measures and therapeutic outcomes J Urol 157 1997 849 854
15. A. Bond, and M. Bader The use of analogue scales in rating subjective feelings Brit J Med Psychol 47 1974 211 218
16. A.K. Slob, J.H.M. Blom, and J.J.W. Bosch Erection problems in medical practice: Differential diagnosis with relatively simple method J Urol 143 1990 46 50
17. J. Mockel, C. Schulman, and J. Sternon Partial androgenic deficit in the aging male Rev Med Brux 23 2002 451 455
18. C. Foresta, N. Caretta, A. Garolla, and M. Rossato Erectile function in elderly: role of androgens J Endocrinol Invest 26 3 suppl. 2003 77 81
19. C.M. Ahn Hs Park, and S.W. Lee The clinical relevance of sex hormone levels and sexual activity in the ageing male BJU Int 89 2002 526 530
20. A. Aversa, A.M. Isidori, M.U. De Martino, M. Caprio, E. Fabbrini, and M. Rocchiett - March Androgens and penile erection: evedence for a direct relation between free testosterone and cavernous vasodilation in men with erectile dysfunction Clin Endocrinol (oxf.) 53 2000 517 522
21. A. Aversa, A.M. Isidori, G. Spera, and A. Lenzi Fabbri: Androgens improve cavernous vasodilation and response to sildenafil in patients with erectile dysfunction. Clin Endocrinol (oxf) 58 2003 632 638
22. E. Wespes The ageing penis World J Urol 20 2002 36 39
23. A. Gomaa, M. Eissa, and A. El Gebaley The effect of topically applied vasoactive agents and testosterone versus testosterone in the treatment of erectile dysfunction in aged men with low sexual interest Int J impot Res 13 2001 93 99
24. A. Nehra, and H. Kulaksizoglu combination therapy for erectile dysfunction: where we are and what's in the future Curr Urol Rep 3 2002 467 470
25. W.D. Steers Viability and safety of combination drug therapies for erectile dysfunction J Urol 170 2 pt 2 2003 S20 S23
26. U. Dunzendorfer, A. Behm, E. Dunzendorfer, and A. Dunzendorfer Drug combination in the therapy of low response to phosphodiesterase 5 inhibitors in patients with erectile dysfunction In Vivo 16 2002 345 348
27. D.G. Dimitriev, S.I. Gamidov, E.B. Mazo, and R.L. Ovenhinnikov A new Approach to raising the efficiency of drug therapy for erectile dysfunction Ter Arkh 74 2002 75 77
28. S.Y. Kalinchenko, G.L. Kozlov, N.P. Gontcharov, and G.V. Katsiya Oral testosterone undecanoate reverses erectile dysfunction associated with diabetes mellitus in patients falling on slidenafil citrate therapy alone Aging Male 6 2003 94 99
29. R. Shabsigh Hypogonadism and erectile dysfunction: the role for testosterone therapy Int J Impot Res 15 Suppl 4 2003 S9 S13
30. R. Stanislavov, and V. Nikolova Treatment of erectile dysfunction with pycnogenol and L-arginine J Sex Marital Ther 29 2003 207 213
31. S. Filippi, C. Crescioli, G.B. Vannelli, A. Fazzini, A. Natali, and J.P. Riffaud Effects of NCX 4050, a new NO donor, in rabbit and human corpus cavernosum Int J Androl 26 2003 101 108
32. H. Padma-Nathan, L. Goldstein, L. Klimberg, C. Coogan, S. Auerbach, and P. Lammers Long-term satefy and efficacy of oral phentolamine mesylate (Vasomax) in men with mild to moderate erectile dysfunction Int J Impot Res 14 2002 266 270
33. J.H. Hagemann, G. Berding, S. Bergh, D.J. Sleep, W.H. Knapp, and C.G. Jonas stief Effect of visual sexual stimuli and apomorphine SL on cerebral activity in men with erectile dysfunction Eur Urol 43 2003 412 420
34. F. Monitorsi, D. Perani, D. Anchisi, A. Salonia, P. Scifo, and P. Rigiroli Apomorphine -induced brain modulation during sexual stimulation: a new lock at central phenomena related to erectile dysfunction Int J Impot Res 15 2003 203 209