Acetohydroxyacid synthase isozyme I from Escherichia coli has unique catalytic and regulatory properties

Biochimica et Biophysica Acta - General Subjects

Volumn 1760, Issue 3, 2006, Pages 356-363

  Vinogradov, Valerie ^a   Vyazmensky, Maria ^a   Engel, Stanislav ^a   Belenky, Inna ^a   Kaplun, Alexander ^a   Kryukov, Olga ^a   Barak, Ze'ev ^a   Chipman, David M ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Allosteric; Isozyme; Oxygenase; Peracetate; R PAC; Valine inhibition

Indexed keywords

ACETOLACTATE SYNTHASE; ACETOLACTATE SYNTHASE ISOENZYME I; BACTERIAL ENZYME; ISOENZYME; OXYGEN; UNCLASSIFIED DRUG; VALINE;

ARTICLE; BIOSYNTHESIS; ENTEROBACTERIACEAE; ENZYME PURIFICATION; ESCHERICHIA COLI; KINETICS; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

ACETOLACTATE SYNTHASE; ACETONE; CLONING, MOLECULAR; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FEEDBACK, BIOCHEMICAL; ISOENZYMES; ISOMERISM; KINETICS; VALINE;

BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; ESCHERICHIA COLI;

EID: 33644911464     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2005.10.008     Document Type: Article

References (30)

1. H.E. Umbarger Biosynthesis of the branched chain amino acids F.C. Neidhardt J.L. Ingraham B.L. Low B. Magasanik M. Schaechter H.E. Umbarger Escherichia coli and Salmonella typhimurium Cellular and Molecular Biology 1996 ASM Press Washington 442 457
2. Z. Barak, D.M. Chipman, and N. Gollop Physiological implications of the specificity of acetohydroxy acid synthase isozymes of enteric bacteria J. Bacteriol. 169 1987 3750 3756
3. S. Epelbaum, R.A. LaRossa, T.K. VanDyk, T. Elkayam, D.M. Chipman, and Z. Barak Branched-chain amino acid biosynthesis in salmonella typhimurium: a quantitative analysis J. Bacteriol. 180 1998 4056 4067
4. Z. Barak, J.M. Calvo, and J.V. Schloss Acetolactate synthase isozyme III from Escherichia coli Methods Enzymol. 166 1988 455 458
5. L. Eoyang, and P.M. Silverman Purification and subunit composition of acetohydroxyacid synthase I from Escherichia coli K-12 J. Bacteriol. 157 1984 184 189
6. J.V. Schloss, D.E. Van Dyk, J.F. Vasta, and R.M. Kutny Purification and properties of Salmonella typhimurium acetolactate synthase isozyme II from Escherichia coli HB101/pDU9 Biochemistry 24 1985 4952 4959
7. S. Mendel, T. Elkayam, C. Sella, V. Vinogradov, M. Vyazmensky, D.M. Chipman, and Z. Barak Acetohydroxyacid synthase: a proposed structure for regulatory subunits supported by evidence from mutagenesis J. Mol. Biol. 307 2001 465 477
8. Y. Zohar, M. Einav, D.M. Chipman, and Z. Barak Acetohydroxyacid synthase from Mycobacterium avium and its inhibition by sulfonylureas and imidazolinones Biochim. Biophys. Acta 1649 2003 97 105
9. I. Porat, M. Vinogradov, M. Vyazmensky, C.-D. Lu, D.M. Chipman, A.T. Abdelal, and Z. Barak Cloning and characterization of acetohydroxyacid synthase from Bacillus stearothermophilus J. Bacteriol. 186 2004 570 574
10. N. Gollop, B. Damri, Z. Barak, and D.M. Chipman Kinetics and mechanism of acetohydroxy acid synthase isozyme III from Escherichia coli Biochemistry 28 1989 6310 6317
11. A. Sutton, and M. Freundlich Regulation by cyclic AMP of the ilvB-encoded biosynthetic acetohydroxy acid synthase in Escherichia coli K-12, MGG Mol. Gen. Genet. 178 1980 179 183
12. F.E. Dailey, J.E. Cronan Jr., and S.R. Maloy Acetohydroxy acid synthase I is required for isoleucine and valine biosynthesis by Salmonella typhimurium LT2 during growth on acetate or long-chain fatty acids J. Bacteriol. 169 1987 917 919
13. F.E. Dailey, and J.E.J. Cronan Acetohydroxy acid synthase I, a required enzyme for isoleucine and valine biosynthesis in Escherichia coli K-12 during growth on acetate as the sole carbon source J. Bacteriol. 165 1986 453 460
14. L.O. Krampitz Preparation and determination of 2-acetolactic acid Arch. Biochem. 17 1948 81
15. J.V. Schloss, and A. Aulabaugh Acetolactate synthase and ketol-acid reductoisomerase: targets for herbicides obtained by screening and de novo design Z. Naturforsch. 45c 1990 544 551
16. T. Newman, P. Friden, A. Sutton, and M. Freundlich Cloning and expression of the ilvB gene of Escherichia coli K-12 Mol. Gen. Genet. 186 1982 378 384
17. S. Engel, M. Vyazmensky, M. Vinogradov, V. Berkovich, A. Bar-Ilan, U. Qimron, Y. Rosiansky, Z. Barak, and D.M. Chipman Role of conserved arginine in the mechanism of acetohydroxyacid synthase J. Biol. Chem. 279 2004 24803 24812
18. S. Mendel, M. Vinogradov, M. Vyazmensky, D.M. Chipman, and Z. Barak The N-terminal domain of the regulatory subunit is sufficient for complete activation of acetohydroxyacid synthase III from Escherichia coli J. Mol. Biol. 325 2003 275 284
19. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
20. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
21. A. Bar-Ilan, V. Balan, K. Tittmann, R. Golbik, M. Vyazmensky, G. Hubner, Z. Barak, and D.M. Chipman Binding and activation of thiamin diphosphate in acetohydroxyacid synthase Biochemistry 40 2001 11946 11954
22. J.M.T. Tse, and J.V. Schloss The oxygenase reaction of acetolactate synthase Biochemistry 32 1993 10398 10403
23. S. Engel, M. Vyazmensky, S. Geresh, Z. Barak, and D.M. Chipman Acetohydroxyacid synthase: a new enzyme for chiral synthesis of R-phenylacetylcarbinol Biotechnol. Bioeng. 83 2003 833 840
24. O. Weinstock, C. Sella, D.M. Chipman, and Z. Barak Properties of subcloned subunits of bacterial acetohydroxy acid synthases J. Bacteriol. 174 1992 5560 5566
25. M. Vyazmensky, C. Sella, Z. Barak, and D.M. Chipman Isolation and characterization of subunits of acetohydroxy acid synthase isozyme III and reconstitution of the holoenzyme Biochemistry 35 1996 10339 10346
26. J. Monod, J. Wyman, and J.P. Changeux On the nature of allosteric transitions: a plausibal model J. Mol. Biol. 12 1965 88 118
27. A. Levitzki Quantitative Aspects of Allosteric Mechanisms 1978 Springer-Verlag Berlin
28. L.M. Abell, and J.V. Schloss Oxygenase side reactions of acetolactate synthase and other carbanion-forming enzymes Biochemistry 30 1991 7883 7887
29. M. Ibdah, A. Bar-Ilan, O. Livnah, J.V. Schloss, Z. Barak, and D.M. Chipman Homology modeling of the structure of bacterial acetohydroxy acid synthase and examination of the active site by site-directed mutagenesis Biochemistry 35 1996 16282 16291
30. K. Tittmann, M. Vyazmensky, G. Hubner, Z. Barak, and D.M. Chipman The carboligation reaction of acetohydroxyacid synthase II: steady-state intermediate distributions in wild type and mutants by NMR Proc. Natl. Acad. Sci. U. S. A. 102 2005 553 558