Report refuting value of immune complexes to diagnose lyme disease is invalid [3]

Clinical and Vaccine Immunology

Volumn 13, Issue 2, 2006, Pages 304-305

  Brunner, Michael ^a  

^a PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY;

ANTIGEN ANTIBODY COMPLEX; DIAGNOSTIC KIT; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOASSAY; IMMUNOGLOBULIN BLOOD LEVEL; LETTER; LYME DISEASE; NEPHELOMETRY; PRIORITY JOURNAL;

ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, BACTERIAL; BORRELIA BURGDORFERI; HUMANS; IMMUNOASSAY; LYME DISEASE;

EID: 33644904591     PISSN: 15566811     EISSN: None     Source Type: Journal    
DOI: 10.1128/CVI.13.2.304-306.2006     Document Type: Letter

References (11)

1. Brunner, M. 2001. New method for detection of Borrelia burgdorferi antigen complexed to antibody in seronegative Lyme disease. J. Immunol. Methods 249:185-190.
2. Brunner, M., and L. H. Sigal. 2000. Immune complexes from serum of patients with Lyme disease contain Borrelia burgdorferi antigen and antigen-specific antibodies: potential use for improved testing. J. Infect. Dis. 182:534-539.
3. Brunner, M., and L. H. Sigal. 2001. Use of serum immune complexes in a new test that accurately confirms early Lyme disease and active infection with Borrelia burgdorferi. J. Clin. Microbiol. 39:3213-3221.
4. Brunner, M., S. Stein, P. D. Mitchell, and L. H. Sigal. 1998. Immunoglobulin M capture assay for serologic confirmation of early Lyme disease: analysis of immune complexes with biotinylated Borrelia burgdorferi sonicate enhanced with flagellin peptide epitope. J. Clin. Microbiol. 36:1074-1080.
5. Digeon, M., M. Laver, J. Riza, and J. F. Bach. 1977. Detection of circulating immune complexes in human sera by simplified assays with polyethylene glycol. J. Immunol. Methods 16:165-183.
6. Dobson, S. R., L. H. Taber, and R. E. Baughn. 1988. Characterization of the components in circulating immune complexes from infants with congenital syphilis. J. Infect. Dis. 158:940-947.
7. Inman, R. D., P. B. Redecha, S. J. Knechtle, E. S. Schned, I. van de Rijn, and C. L. Christian. 1982. Identification of bacterial antigens in circulating immune complexes of infective endocarditis. J. Clin. Investig. 70:271-280.
8. Jones, V. E., and E. Orlans. 1981. Isolation of immune complexes and characterisation of their constituent antigens and antibodies in some human diseases: a review. J. Immunol. Methods 44:249-270.
9. Marques, A. R., R. L. Hornung, L. Dally, and M. T. Philipp. 2005. Detection of immune complexes is not independent of detection of antibodies in Lyme disease patients and does not confirm active infection with Borrelia burgdorferi. Clin. Diagn. Lab. Immunol. 12:1036-1040.
10. Schutzer, S. E., P. K. Coyle, A. L. Belman, M. G. Golightly, and J. Drulle. 1990. Sequestration of antibody to Borrelia burgdorferi in immune complexes in seronegative Lyme disease. Lancet 335:312-315.
11. Theofilopoulos, A. N., and F. J. Dixon. 1980. Immune complexes in human diseases: a review. Am. J. Pathol. 100:529-594.