Attenuation by Nardostachys jatamansi of 6-hydroxydopamine-induced parkinsonism in rats: Behavioral, neurochemical, and immunohistochemical studies

Pharmacology Biochemistry and Behavior

Volumn 83, Issue 1, 2006, Pages 150-160

  Ahmad, Muzamil ^a,c   Yousuf, Seema ^a   Khan, M Badruzzaman ^a   Hoda, Md Nasrul ^a   Ahmad, Abdullah Shafique ^a   Ansari, Mubeen Ahmad ^a   Ishrat, Tauheed ^a   Agrawal, Ashok Kumar ^b   Islam, Fakhrul ^a  

^a HAMDARD UNIVERSITY   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

6 hydroxydopamine; Dopamine; Herbal drugs; Nardostachys jatamansi; Neuroprotection; Oxidative stress; Parkinson's disease

Indexed keywords

ALCOHOL; ANTIOXIDANT; ASCORBIC ACID; BIOGENIC AMINE; CATALASE; CATECHOLAMINE; DOPAMINE RECEPTOR; DRUG VEHICLE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; NARDOSTACHYS JATAMANSI EXTRACT; OXIDOPAMINE; PLANT EXTRACT; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BODY WEIGHT; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE METABOLISM; DRUG EFFECT; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIPID PEROXIDATION; LOCOMOTION; MALE; MOTOR COORDINATION; NARDOSTACHYS; NERVOUS SYSTEM INJURY; NEUROCHEMISTRY; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BINDING; SUBSTANTIA NIGRA;

ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; CATALASE; DOPAMINE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; MOTOR ACTIVITY; NARDOSTACHYS; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; PLANT ROOTS; PSYCHOMOTOR PERFORMANCE; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; STEREOTYPED BEHAVIOR; SUPEROXIDE DISMUTASE; SYMPATHOLYTICS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TYROSINE 3-MONOOXYGENASE;

ANIMALIA; NARDOSTACHYS; NARDOSTACHYS JATAMANSI;

EID: 33644894167     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2006.01.005     Document Type: Article

References (59)

1. A.K. Agrawal, R. Hussin, R. Raghubir, A. Kumar, and P.K. Seth Neurobehavioral, neurochemical and electrophysiological studies in 6-hydroxydopamine lesioned and neural transplanted rats Int J Dev Neurosci 13 2 1995 105 111
2. M. Ahmad, S. Saleem, A.S. Ahmad, M.A. Ansari, S. Yousuf, and M.N. Hoda Neuroprotective effects of Withania somnifera on 6-hydroxydopamine induced Parkinsonism in rats Hum Exp Toxicol 24 3 2005 137 147
3. M. Ahmad, S. Saleem, A.S. Ahmad, S. Yousuf, M.A. Ansari, and M.B. Khan Ginkgo biloba affords dose-dependent protection against 6-hydroxydopamine- induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences J Neurochem 93 1 2005 94 104
4. S. Ali, K.A. Ansari, M.A. Jafri, H. Kabeer, and G. Diwakar Nardostachys jatamansi protects against liver damage induced by thio acetamide in rats J Ethnopharmacol 71 2000 359 363
5. R.B. Arora Nardostachys jatamansi - a chemical, pharmacological and clinical appraisal Monograph Special Series vol. 51 1965 Indian Council of Medical Research New Delhi
6. M. Athar, H. Mukhtar, D.R. Bickers, I.U. Khan, and B. Kalyanaraman Evidence for the metabolism of tumor promoter organic hydroperoxides into free radicals by human carcinoma skin keratinocytes: an ESR-spin trapping study Carcinogenesis 10 1989 1499 1503
7. A. Bagchi, Y. Oshima, and H. Hikino Neoligans and lignans of Nardostachys jatamansi roots Planta Med 57 1991 96 97
8. O. Bandmann, D.C. Marsden, and N.W. Wood Genetic aspects of Parkinson's disease Mov Disord (Review) 13 1998 203 211
9. C. Beauchamp, and I. Fridovich Superoxide dismutase: improved assays and an assay applicable to acrylamide gels Anal Biochem 44 1971 276 287
10. J.S. Beckman, T.W. Beckman, and J. Chen Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide Proc Natl Acad Sci U S A 87 1990 1620 1624
11. B.R. Bloem, I. Irwin, O.J.S. Buruma, J. Haan, R.A.C. Roos, and J.W. Tetrud The MPTP model: versatile contributions to the treatment of idiopathic Parkinson's disease J Neurol Sci 97 1990 273 293
12. C.R. Breese, and G.R. Breese The use of neurotoxin to lesion catecholamine neurons to model clinical disorder R.M. Kostrzewa Highly selective neurotoxin: basic and clinical applications 1998 Humana Press New Jersey 19 73
13. J.L. Cadet, M. Katz, V. Jackson-Lewis, and S. Fahn Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats. Behavioral and biochemical evidence Brain Res 476 1989 10 15
14. D.B. Calne, and J.W. Langston Aetiology of Parkinson's disease Lancet II 1983 1457 1459
15. R.K. Carder, D. Jackson, H.J. Morris, R.D. Lund, and M.J. Zigmond Dopamine released from mesencephalic transplants restores modulation of striatal acetylcholine release after neonatal 6-OHDA: an in vitro analysis Exp Neurol 105 1989 251 259
16. I. Carlberg, and B. Mannervik Glutathione reductase levels in rat brain J Biol Chem 250 1975 5475 5480
17. A. Chatterji, and S.C. Prakashi The treatise on Indian medicinal plants vol. 5 1997 National Institute of Science Communication New Delhi 99 100
18. R.K. Chaturvedi, A.K. Agrawal, K. Seth, S. Shukla, S. Chauhan, and Y. Shukla Effect of glial cell line-derived neurotrophic factor (GDNF) co-transplantation with fetal ventral mesencephalic cells (VMC) on functional restoration in 6-hydroxydopamine (6-OHDA) lesioned rat model of Parkinson's disease: neurobehavioral, neurochemical and immunohistochemical studies Int J Dev Neurosci 21 7 2003 391 400
19. C. Cohen The pathobiology of Parkinson's disease: biochemical aspects of dopamine neuron senescence J Neural Transm Suppl. 19 1983 89 103
20. G. Cohen Oxyradical toxicity in catecholamine neurons Neurotoxicol 5 1984 77 82
21. G. Cohen, R.E. Heikkila, B. Allis, F. Cabbat, D. Dembiec, and D. MacNamee Destruction of sympathetic nerve terminals by 6-hydroxydopamine: protection by 1-phenyl-3-(2-thiazolyl)-2-thiourea, diethylthiocarbamate, methimazole, cysteamine, ethanol and n-butanol J Pharmacol Exp Ther 199 1976 336 352
22. A. Coliborne Catalase activity R.A. Green Wald CRC handbook of methods for oxygen radical research 1985 CRC Press Florida 283 284
23. R.T. Dean, C.R. Roberts, and W. Jessup Fragmentation of extracellular and intracellular polypeptides by free radicals E. Khirallah J. Bond J.W.C. Bird Intracellular protein catabolism 1985 Liss AR New York 341 350
24. M.J. DeVito, and G.C. Wagner Methamphetamine induced neuronal damage: a possible role for free radicals Neuropharmacology 28 1989 1145 1150
25. J.M. Fearnley, and A. Lees Ageing and Parkinson's disease: substantia nigra regional selectivity Brain 114 1991 2283 2301
26. B.A. Freeman, and J.D. Crapo Biology of disease: free radicals and tissue injury Lab Invest 47 1982 412 426
27. I. Fridovich Superoxide dismutases: an adaptation to a paramagnetic gas J Biol Chem 264 1975 19328 19333
28. D.G. Graham On the origin and significance of neuromelanin Arch Pathol Lab Med 103 1979 359 362
29. W.H. Habig, M.J. Pabst, and W.B. Jokoby Glutathione-S-transferase: the first enzymatic step in mercapturic acid formation J Biol Chem 249 1974 7130 7139
30. B. Halliwell, and J.M.C. Gutteridge Oxygen radicals and the nervous system Trends Neurosci 8 1985 22 29
31. E.C. Hirsch Does oxidative stress participate in nerve cell death in Parkinson's disease? Eur Neurol 33 Suppl. 1 1993 52 59
32. P. Jenner, and C.W. Olanow Oxidative stress and the pathogenesis of Parkinson's disease Neurology 47 6 Suppl. 3 1996 161 170
33. D.J. Jollow, J.R. Mitchell, N. Zampagloine, and J.R. Gillete Bromobenzene-induced liver necrosis: protective role of glutathione and evidence for 3, 4 bromobenzeneoxide as the hepatotoxic intermediate Pharmacology 11 1974 151 169
34. R. Kumar, A.K. Agarwal, and P.K. Seth Free radical-generated neurotoxicity of 6-hydroxidopamine J Neurochem 64 1995 1703 1707
35. O.H. Lowry, N.J. Rosenbrough, A.L. Far, and R.J. Randall Protein measurement with Folin phenol reagent J Biol Chem 193 1951 265 275
36. J. Mohandas, J.J. Marshall, G.G. Duggin, J.S. Horvath, and D. Tiller Differential distribution of glutathione and glutathione related enzymes in rabbit kidneys: possible implication in analgesic neuropathy Cancer Res 4 1984 5086 5091
37. V.V. Myllyla, K.A. Sotaniemi, J.A. Vuorinen, and E.H. Heinone Seligiline as initial treatment in de novo parkinsonian patients Neurology 42 1992 339 343
38. C. Mytilineou, E.K. Leonardi, P. Radcliffe, E.H. Heinonen, and S.K. Han Deprenyl and desmethylselegiline protect mesencephalic neurons from toxicity induced by glutathione depletion J Pharmacol Exp Ther 284 1998 700 706
39. I. Oreland Monoamine oxidase, dopamine and Parkinson's disease Acta Neurol Scand Suppl. 136 1991 60 65
40. Parkinson Study Group (United Kingdom) Effect of deprenyl on the progression of disability in early Parkinson's disease N Engl J Med 321 1989 1364 1371
41. G. Paxinos, and C. Watson The rat brain stereotaxic coordinates 1982 Academic Press Sydney
42. D.A. Perese, J. Ulman, J. Viola, S.E. Ewing, and K.S. Bankiewicz A 6-hydroxydopamine-induced selective Parkinsonian rat model Brain Res 494 1989 285 293
43. A.S. Perumal, V.B. Gopal, W.K. Tordzro, T.B. Cooper, and J.L. Cadet Vitamin E attenuates the toxic effects of 6-hydroxydopamine on free radical scavenging systems in rat brain Brain Res Bull 29 1992 699 701
44. E. Pileblad, T. Magnusson, and B. Fornstedt Reduction of brain glutathione by l-buthionine sulfoximine potentiates the dopamine depleting action of 6-hydroxydopamine in rat striatum J Neurochem 52 1989 978 980
45. V.M. Prabhu, S.K. Karandh, A. Rao, P.M. Vidya, and K. Sudhakar Effect of Nardostachys jatamansi on biogenic amines and inhibitory amino acids on rat brain Planta Med 60 1994 114 217
46. C. Sachs, and G. Jonsson Mechanisms of action of 6-hydroxydopamine Biochem Pharmacol 24 1975 1 8
47. S. Salim, M. Ahmad, I. Sayeed, A.S. Ahmad, and F. Islam Protective effect of Nardostachys jatamansi in rat cerebral ischemia Pharmacol Biochem Behav 74 2 2003 481 486
48. R.K.W. Schwarting, and J.P. Huston The unilateral 6-hydroxydopamine lesion model in behavioural brain research: analysis of functional deficits, recovery and treatments Prog Neurobiol 50 1996 275 331
49. Z.A. Shah, and S.B. Vohora Antioxidant/restorative effects of calcined gold preparations used in Indian systems of medicine against global and focal models of ischaemia Pharmacol Toxicol 90 5 2002 254 259
50. T.F. Slater Free radical mechanisms in tissue injury Biochem J 222 1984 1 12
51. Y. Sun Free radicals, antioxidant enzymes and carcinogenesis Free Radic Biol Med 8 1990 583 599
52. Y.B. Tripathi, E. Tripharhi, and A. Upadhyay Antilipid peroxidative property of Nardostachys jatamansi Indian J Exp Biol 34 1996 1150 1151
53. M.R. Uniyal, and R.K. Issar Commercially and traditionally important medicinal plants of Mandakini Valley of Uttrakhand, Himalayas J Res Indian Med 4 1969 83
54. H.C. Utley, F. Bernheim, and P. Hochslein Effect of sulfhydryl reagent on peroxidation in microsome Arch Biochem Biophys 260 1967 521 531
55. U. Wüllner, P.A. Loschmann, and J.B. Schulz Glutathione depletion potentiates MPTP and MPPC toxicity in nigral dopaminergic neurones NeuroReport 7 1996 921 923
56. M.B.H. Youdim, and L. Lavie Selective MAO-A and B inhibitors, radical scavenger, and nitric oxide synthase in Parkinson's disease Life Sci 55 1994 2077 2082
57. K.S. Zafar, I. Sayeed, A. Siddiqui, M. Ahmad, S. Salim, and F. Slam Dose-dependent protective effect of selenium in partial lesion model of Parkinson's disease: neurobehavioral and neurochemical evidences J Neurochem 84 2003 438 446
58. K.S. Zafar, A. Siddiqui, I. Sayeed, M. Ahmad, S. Saleem, and F. Islam Protective effect of adenosine in rat model of Parkinson's disease: neurobehavioral and neurochemical evidences J Chem Neuroanat 26 2003 143 151
59. I. Ziv, E. Melamed, and N. Nardi Role of apoptosis in the pathogenesis of Parkinson's disease: a novel therapeutic opportunity Mov Disord 13 1998 865 870