Plasma levels of corticotroph-type pro-opiomelanocortin derivatives such as β-lipotropin, β-endorphin(1-31), or adrenocorticotropic hormone are correlated with severity of postoperative pain

Clinical Journal of Pain

Volumn 22, Issue 2, 2006, Pages 113-121

  Matejec, Reginald ^a   Harbach, Heinz W ^a   Bödeker, Rolf H ^a   Hempelmann, Gunter ^a   Teschemacher, Hansjörg ^b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

Author keywords

endorphin(1 31) in plasma; Functional significance of POMC fragments in plasma; Melanotroph type pro opiomelanocortin system; Spinal anesthesia

Indexed keywords

BETA ENDORPHIN; BETA LIPOTROPIN; CORTICOTROPIN; CORTICOTROPIN DERIVATIVE; PROOPIOMELANOCORTIN; BUFFER; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; HYDROCORTISONE; PEPTIDE FRAGMENT;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HIP ARTHROPLASTY; HORMONE BLOOD LEVEL; HUMAN; IMMUNOREACTIVITY; KNEE ARTHROPLASTY; MALE; PAIN ASSESSMENT; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; SPINAL ANESTHESIA; VISUAL ANALOG SCALE; BLOOD; BLOOD SAMPLING; DRUG EFFECT; HYPOPHYSIS; METABOLISM; MIDDLE AGED; PROSPECTIVE STUDY;

ADRENOCORTICOTROPIC HORMONE; AGED; ANESTHESIA, SPINAL; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; BETA-ENDORPHIN; BETA-LIPOTROPIN; BLOOD SPECIMEN COLLECTION; BUFFERS; FEMALE; HUMANS; HYDROCORTISONE; INDICATORS AND REAGENTS; MALE; MIDDLE AGED; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PEPTIDE FRAGMENTS; PITUITARY GLAND; PRO-OPIOMELANOCORTIN; PROSPECTIVE STUDIES;

EID: 33644890448     PISSN: 07498047     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ajp.0000152327.01890.d6     Document Type: Article

References (44)

1. Bertagna X. Proopiomelanocortin-derived peptides. Endocrinol Metab Clin N Am. 1994;23:467-485.
2. Castro MG, Morrison E. Post-translational processing of proopiomelanocortin in the pituitary and in the brain. Crit Rev Neurobiol. 1997;11:35-57.
3. Raffin-Sanson ML, de Keyzer Y, Bertagna X. Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions. Eur J Endocrinol. 2003;149:79-90.
4. Glembotski CC. Acetylation of alpha-melanotropin and beta-endorphin in the rat intermediate pituitary. Subcellular localization. J Biol Chem. 1982;257:10493-10500.
5. Evans VR, Manning AB, Bernard LH, et al. α-melanocyte-stimulating hormone and N-acetyl-β-endorphin immunoreactivities are localized in the human pituitary but are not restricted to the zona intermedia. Endocrinology. 1994;134:97-106.
6. Walsh J, Puig MM, Lovitz MA, et al. Premedication abolishes the increase in plasma beta-endorphin observed in the immediate preoperative period. Anesthesiology. 1987;66:402-405.
7. Marschall K, Schlesinger MD, Turndorf H, et al. Beta-endorphin and ACTH levels in the perioperative period. Gen Pharmacol. 1989;20:399-402.
8. Le Blanc-Louvry I, Coquerel A, Koning E, et al. Operative stress response is reduced after laparoscopic compared to open cholecystectomy. Dig Dis Sci. 2000;45:710-720.
9. Dubois M, Pickar D, Cohen MR, et al. Surgical stress in humans is accompanied by an increase in plasma beta-endorphin immunoreactivity. Life Sci. 1981;29:1249-1254.
10. Hargreaves KM, Dionne RA, Mueller GP. Plasma β-endorphin-like immunoreactivity, pain and anxiety following administration of placebo in oral surgery patients. J Dent Res. 1983;62:1170-1173.
11. Lacoumenta S, Yeo TH, Burrin JM, et al. Fentanyl and the β-endorphin, ACTH and glucoregulatory hormonal response to surgery. Br J Anaesth. 1987;59:713-720.
12. Janicki PK, Erskine R, van der Watt ML. Plasma concentrations of immunoreactive beta-endorphin and substance P in patients undergoing surgery under general vs. spinal anesthesia. Horm Metab Res. 1993;25:131-133.
13. Gordon SM, Dionne RA, Brahim J, et al. Blockade of peripheral neuronal barrage reduces postoperative pain. Pain. 1997;70:209-215.
14. Mizutani A, Hattori S, Yoshitake S, et al. Effect of additional general anesthesia with propofol, midazolam or sevoflurane on stress hormone levels in hysterectomy patients, receiving epidural anesthesia. Acta Anaesthesiol Belg. 1998;49:133-139.
15. Houweling PL, Inescu TI, Braams R, et al. Hormonal responses and pharmacokinetics after intradural (spinal) morphine and general anesthesia for abdominal aortic surgery. Clin. Drug Invest. 1999;17:357-364.
16. Acosta F, Moreno J, Fuente T, et al. Influence of surgical technique on the plasma concentration of beta-endorphin during liver transplantation. Transplant Proc. 2000;32:2658.
17. Hargreaves KM, Schmidt EA, Mueller GP, et al. Dexamethasone alters plasma levels of beta-endorphin and postoperative pain. Clin Pharmacol Ther. 1987;42:601-607.
18. Roth-Isigkeit AK, Schmucker P. Postoperative dissociation of blood levels of cortisol and adrenocorticotropin after coronary artery bypass grafting surgery. Steriods. 1997;62:695-699.
19. Pavlova ZV, Laktionov KP, Isakova ME, et al. Concentration of β-endorphin in blood plasma and cerebrospinal fluid during various types of anesthesia in the early postoperation period and in incurable oncological patients. Bull Exp Biol Med. 1999;128:1150-1154.
20. Porro CA, Faccinetti F, Bertellini E, et al. Beta-lipotropin is the major component of the plasma opioid response to surgical stress in humans. Life Sci. 1987;41:2581-2588.
21. Smith AI, Cheng MC, Funder JW. The identification and characterization of α-N-acetylated β-endorphin in the human pituitary gland. FEBS Lett. 1985;185:109-111.
22. Harbach HW, Hell K, Gramsch C, et al. β-endorphin (1-31) in the plasma of male volunteers undergoing physical exercise. Psychoneuroendocrinology. 2000;25:551-562.
23. Wiedemann K, Teschemacher H. Determination of β-endorphin and fragments thereof in human plasma using high-performance liquid chromatography and a multiple radioimmunoassay system. Pharmacol Res Commun. 1986;3:142-149.
24. Hunter WM, Greenwood FC. Preparation of iodine-131 labeled human growth hormone of high specific activity. Nature. 1962;194:495-496.
25. Schulz A, Harbach H, Katz N, et al. β-Endorphin immunoreactive material and authentic β-endorphin in the plasma of males undergoing anaerobic exercise on a rowing ergometer. Int J Sports Med. 2000;21:513-517.
26. Matejec R, Schulz A, Harbach HW, et al. Effects of tourniquet-induced ischemia on the release of proopiomelanocortin derivatives determined in peripheral blood plasma. J Appl Physiol. 2004;97:1040-1045.
27. Hollander M, Wolfe DA. Nonparametric Statistical Methods. New York, NY: John Wiley and Sons; 1973:33-64.
28. Rosendahl W, Schulz U, Teufel T, et al. Surgical stress and neuroendocrine responses in infants and children. J Pediatr Endocrinol Metab. 1995;8:187-194.
29. Kieffer BL. Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides. Cell Mol Neurobiol. 1995;15:615-635.
30. Lautenbacher S, Roscher S, Kohl G, et al. Corticotropin-releasing-hormone lacks analgesic properties: an experimental study in humans, using non-inflammatory pain. Pain. 1999;83:1-7.
31. Lacoumenta S, Yeo TH, Burrin JM, et al. Beta-endorphin infusion fails to modulate the hormonal and metabolic response to surgery. Clin Endocrinol. 1987;26:657-666.
32. Czlonkowski A, Stein C, Herz A. Peripheral mechanisms of opioid antinociception in inflammation: involvement of cytokines. Eur J Pharmacol. 1993;242:229-235.
33. Schäfer M, Carter L, Stein C. Interleukin 1β and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proc Natl Acad Sci USA. 1994;91:4219-4223.
34. Stein C. The control of pain in peripheral tissue by opioids. N Engl J Med. 1995;332:1685-1690.
35. Janson W, Stein C. Peripheral opioid analgesia. Curr Pharm Biotechnol. 2003;4:270-274.
36. Bigliardi P-L, Buchner S, Rufli T, et al. Specific stimulation of migration of human keratinocytes by μ-opiate receptor agonists. J Recept Signal Transduct Res. 2002;22:191-199.
37. Bigliardi P-L, Sumanovski LT, Buchner S, et al. Different expression of μ-opiate receptor in chronic and acute wounds and the effect of β-endorphin on transforming growth factor beta type II receptor and cytokeratin 16 expression. J Invest Dermatol. 2003;120:145-152.
38. Cepeda MS, Lipkowski AW, Langlade A, et al. Local increases of subcutaneous beta-endorphin immunoreactivity at the site of thermal injury. Immunopharmacology. 1993;25:205-213.
39. Sibinga NE, Goldstein A. Opioid peptides and opioid receptors in cells of the immune system. Annu Rev Immunol. 1988;6:219-249.
40. Teschemacher H, Koch G, Scheffler H, et al. Opioid peptides: immunological significance? Ann N Y Acad Sci. 1990;594:66-77.
41. Carr DJJ. The role of endogenous opioids and their receptors in the immune system. Proc Soc Exp Biol Med. 1991;198:710-720.
42. Catania A, Lipton JM. The neuropeptide alpha-melanocyte-stimulating hormone: a key component of neuroimmunomodulation. Neuroimmunomodulation. 1994;1:93-99.
43. Berczi I, Chalmers I-M, Nagy E, et al. The immune effects of neuropeptides. Baillieres Clin Rheumatol. 1996;10:227-257.
44. Matejec R, Ruwoldt R, Bödeker RH, et al. Release of β-endorphin immunoreactive material under perioperative conditions into blood or cerebrospinal fluid: significance for postoperative pain? Anest. Anal. 2003;96:481-486.