Saving cone cells in hereditary rod diseases: A possible role for rod-derived cone viability factor (RdCVF) therapy

Retina

Volumn 25, Issue 8 SUPPL., 2005, Pages

  Sahel, Josi Alain ^a,b,c  

^a INSERM   (France)

^b France's Institute of Vision   (France)

^c CENTRE HOSPITALIER NATIONAL D OPHTALMOLOGIE DES QUINZE VINGTS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; OXIDOREDUCTASE; PLASMID DNA; PROTEIN; ROD DERIVED CONE VIABILITY FACTOR; THIOREDOXIN; UNCLASSIFIED DRUG; ROD DERIVED CONE VIABILITY FACTOR, HUMAN; ROD-DERIVED CONE VIABILITY FACTOR, HUMAN;

CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL POPULATION; CELL SURVIVAL; CELL VIABILITY; CONFERENCE PAPER; DNA PURIFICATION; ENZYME ACTIVITY; GENE DELIVERY SYSTEM; GENE EXPRESSION; NEUROPROTECTION; NONHUMAN; RETINA; RETINA CONE; RETINA MACULA AGE RELATED DEGENERATION; RETINA ROD; RETINITIS PIGMENTOSA; VIRUS VECTOR; ANIMAL; EYE DISEASE; HUMAN; PATHOLOGY; PHYSIOLOGY; RETINA DEGENERATION; REVIEW;

ANIMALS; CELL SURVIVAL; CONES (RETINA); EYE DISEASES, HEREDITARY; HUMANS; RETINAL DEGENERATION; RODS (RETINA); THIOREDOXIN;

EID: 33644873918     PISSN: 0275004X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006982-200512001-00015     Document Type: Conference Paper

References (6)

1. Fintz AC, Audo I, Hicks D, et al. Partial characterization of retina-derived cone neuroprotection in two culture models of photoreceptor degeneration. Invest Ophthalmol Vis Sci 2003;44:818-825.
2. Léveillard T, Mohand-Saïd S, Lorentz O, et al. Identification and characterization of rod-derived cone viability factor. Nat Genet 2004;36:755-759.
3. Adler R. Preparation, enrichment, and growth of purified cultures of neurons and photoreceptors from chick embryos and from normal and mutant mice. Methods Neurosci 1990;2:134-150.
4. Curcio CA, Millican CL, Allen KA, Kalina RE. Ageing of the human photoreceptor mosaic: evidence for selective vulnerability of rods in central retina. Invest Ophthalmol Vis Sci 1993;34:3278-3296.
5. Curcio CA, Medeiros NE, Millican CJ. Photoreceptor loss in age-related macular degeneration. Invest Ophthalmol Vis Sci 1996;37:1236-1249.
6. Scholl HP, Bellmann C, Dandekar SS, et al. Photopic and scotopic fine matrix mapping of retinal areas of increased fundus autofluorescence in patients with age-related maculopathy. Invest Ophthalmol Vis Sci 2004;45:574-583.