Iron bioavailability of hemoglobin from soy root nodules using a caco-2 cell culture model

Journal of Agricultural and Food Chemistry

Volumn 54, Issue 4, 2006, Pages 1518-1522

  Proulx, Amy K ^a   Reddy, Manju B ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Heme iron; Iron bioavailability; Leghemoglobin; Soy root nodules

Indexed keywords

IRON; LEGHEMOGLOBIN;

ARTICLE; BIOAVAILABILITY; BIOLOGICAL MODEL; CELL STRAIN CACO 2; CHEMISTRY; HUMAN; PLANT ROOT; SOYBEAN;

BIOLOGICAL AVAILABILITY; CACO-2 CELLS; HUMANS; IRON; LEGHEMOGLOBIN; MODELS, BIOLOGICAL; PLANT ROOTS; SOYBEANS;

BOVINAE; FABACEAE; ZEA MAYS;

EID: 33644872986     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf052268l     Document Type: Article

References (32)

1. World Health Organization. Nutrition for health and development, Global agenda for combating malnutrition. Progress Report; 2000.
2. Lynch, S. R.; Dassenko, S. A.; Morck, T. A.; Beard, J. L.; Cook, J. D. Soy protein products and heme iron absorption in humans. Am. J. Clin. Nutr. 1985, 41, 13-20.
3. Arredondo-Peter, R.; Hargrove, M. S.; Moran, J. F.; Sarath, G.; Klucas, R. V. Plant hemoglobins. Plant physiol. 1998, 118, 1121-1125.
4. Kundu, S.; Trent, J. T., III.; Hargrove, M. S.; Plants, humans and hemoglobins. Trends Plant Sci. 2003, 8, 387-393.
5. Ollis, D. L.; Appleby, C. A.; Colman, P. M.; Cutten, A. E.; Guss, J. M. Crystal structure of soybean ferric leghaemoglobin a nicotinate at a resolution of 3.3A. Aust. J. Chem. 1983, 36, 451-468.
6. Behlke, J.; Sievers, G.; Ellfolk, N. 1971 The Primary Structure of Soybean Leghemoglobin. Acta Chem. Scand. 1971, 25, 3532.
7. Gualtieri, G.; Bisseling, T. The evolution of nodulation. Plant Mol. Biol. 2000, 42, 181-194.
8. Proulx, A. K. Characterization of the Iron Unavailability of Soy Root Nodules and Soy Leghemoglobin; University of Guelph, Canada, 2004.
9. Au, A. P.; Reddy, M. B. Caco-2 cells can be used to assess human iron bioavailability from a semipurified meal. J. Nutr. 2000, 130, 1329-1334.
10. Yun, S.; Habicht, J. P.; Miller, D. D.; Glahn, R. P. An in vitro digestion/Caco-2 cell culture system accurately predicts the effects of ascorbic acid and polyphenolic compounds on iron bioavailability in humans. J. Nutr. 2004, 134, 2717-2721.
11. Uc, A.; Stokes, J. B.; Britigan, B. E. Heme transport exhibits polarity in Caco-2 cells: evidence for an active and membrane protein-mediated process. Am. J. Physiol. Gastrointest. Liver Physiol. 2004 287, G1150-G1157.
12. Follett, J. R.; Suzuki, Y. A.; Lonnerdal, B. High specific activity heme-Fe and its application for studying heme-Fe metabolism in Caco-2 cell monolayers. Am. J. Physiol. Gastrointest. Liver Physiol. 2002, 283, G1125-G1131.
13. Chidambaram, M. V.; Reddy, M. B.; Thompson, J. L.; Bates, G. W. In vitro studies of iron bioavailability. Probing the concentration and oxidation-reduction of pinto bean iron with ferrous chromogens. Biol. Trace Elem. Res. 1989, 19, 25-40.
14. Torrance, J. D.; Bothwell, T. H. A simple technique for measuring storage iron concentrations in formalinised liver samples. S. Afr. J. Med. Sci. 1968 33, 9-11.
15. Glahn, R. P.; Lee, O. A.; Yeung, A.; Goldman, M. I.; Miller, D. D. Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model. J. Nutr. 1998, 128, 1555-1561.
16. Jovani, M.; Barbera, R.; Farre, R.; Martin de Aguilera, E. Calcium, iron, and zinc uptake from digests of infant formulas by Caco-2 cells. J. Agric. Food Chem. 2001, 49, 3480-3485.
17. Layrisse, M.; Martinez-Torres, C. Model for measuring dietary absorption of heme iron: test with a complete meal. Am. J. Clin. Nutr. 1972, 25, 401-411.
18. Conrad, M. E.; Benjamin, B. I.; Williams, H. L.; Foy, A. L. Human absorption of hemoglobin-iron. Gastroenterology 1967, 53, 5-10.
19. Takkunen, H.; Seppanen, R. Iron deficiency and dietary factors in Finland. Am. J. Clin. Nutr. 1975, 28, 1141-1147.
20. Gibson, S.; Ashwell, M. The association between red and processed meat consumption and iron intakes and status among British adults. Public Health Nutr. 2003, 6, 341-350.
21. World Health Organization. Iron Deficiency Anaemia: Assessment, Prevention and Control. 2001.
22. Reddy, M. B.; Cook, J. D. Assessment of dietary determinants of nonheme-iron absorption in humans and rats. Am. J. Clin. Nutr. 1991, 54, 723-728.
23. Vaghefi, N.; Nedjaoum, F.; Guillochon, D.; Bureau, F.; Arhan, P.; Bougle, D. Iron absorption from concentrated hemoglobin hydrolysate by rat. J. Nutr. Biochem. 2005, 16, 347-352.
24. Johnson, P. E.; Lukaski, H. C.; Bowman, T. D. Effects of level and saturation of fat and iron level and type in the diet on iron absorption and utilization by the rat. J. Nutr. 1987, 117, 501-507.
25. Hallberg, L.; Brune, M.; Erlandsson, M.; Sandberg, A. S.; Rossander-Hulten, L. Calcium: effect of different amounts on nonheme- and heme-iron absorption in humans. Am. J. Clin. Nutr. 1991, 53, 112-119.
26. Hallberg, L.; Rossander-Hulthen, L.; Brune, M.; Gleerup, A. Inhibition of haem-iron absorption in man by calcium. Br. J. Nutr. 1993, 69, 533-540.
27. Anderson, R. A.; Vojnovich, C.; Bookwalter, G. N. Iron Enrichment of Dry-Milled Corn Products. Cereal Chem. 1976, 53, 937-946.
28. Dary, O. Staple food fortification with iron: a multifactorial decision. Nutr. Rev. 2002, 60, S34-S41.
29. Rehner, G.; Walter, T. Effect of Maillard products and lysinoalanine on the bioavailability of iron, copper and zinc. Z. Ernahrungswiss. 1991, 30, 50-55.
30. Yeung, C. K.; Miller, D. D.; Cheng, Z.; Glahn, R. Bioavailability of Elemental Iron Powders in Bread Assessed with an In vitro Digestion/Caco-2 Cell Culture Model. J. Food. Sci 2005, 70, S199-S203.
31. Swain, J. H.; Tabatabai, L. B.; Reddy, M. B. Histidine content of low-molecular-weight beef proteins influences nonheme iron bioavailability in Caco-2 cells. J. Nutr. 2002, 132, 245-251.
32. Huh, E. C.; Hotchkiss, A.; Brouillette, J.; Glahn, R. P. Carbohydrate fractions from cooked fish promote iron uptake by Caco-2 cells. J. Nutr. 2004, 134, 1681-1689.