Hydrogen sulfide as a new endogenous gaseous transmitter in the cardiovascular system

Current Vascular Pharmacology

Volumn 4, Issue 1, 2006, Pages 17-22

  Tang, Chaoshu ^a   Li, Xiaohui ^a   Du, Junbao ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 MERCAPTOSULFURTRANSFERASE; CYSTATHIONINE BETA SYNTHASE; CYSTATHIONINE GAMMA LYASE; CYSTEINE; HYDROGEN SULFIDE; SULFURTRANSFERASE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; CYSTATHIONINURIA; ENZYME DEFICIENCY; HEART MUSCLE INJURY; HUMAN; HYPERTENSION; IN VIVO STUDY; NERVOUS SYSTEM; NEUROMODULATION; NONHUMAN; NONSENSE MUTATION; PATHOGENESIS; PATHOPHYSIOLOGY; PULMONARY HYPERTENSION; REVIEW; SHOCK; SMOOTH MUSCLE RELAXATION; ANIMAL; DRUG EFFECT; METABOLISM; TISSUE DISTRIBUTION;

ANIMALS; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; HUMANS; HYDROGEN SULFIDE; TISSUE DISTRIBUTION;

EID: 33644868603     PISSN: 15701611     EISSN: None     Source Type: Journal    
DOI: 10.2174/157016106775203144     Document Type: Review

References (59)

1. Warenycia MW, Goodwin LR, Benishin CG, Reiffenstein RJ, Francom DM, Taylor JD, et al. Acute hydrogen sulfide poisoning: demonstration of selective uptake of sulfide by the brainstem by measurement of brain sulfide levels. Biochem Pharmacol 1989; 38: 973-981.
2. Goodwin LR, Francom D, Dieken FP, Taylor JD, Warenycia MW, Reiffenstein RJ, et al. Determination of sulfide in brain tissue by gas dialysis/ion chromatography: postmortem studies and two case reports. J Analyt Toxicol 1989; 13: 105-109.
3. Awata S, Nakayama K, Suzuki I, Sugahara K, Kodama H. Changes in cystathionine gamma-lyase in various regions of rat brain during development. Biochem Mol Biol Int 1995; 35: 1331-1338.
4. Griffith OW. Mammalian sulfur aminoacid metabolism: an overview. Method Enzymol 1987; 143: 366-376.
5. Swaroop M, Bradley K, Ohura T, Tahara T, Roper MD, Rosenberg LE, et al. Rat cystathionine β-synthase. J Biol Chem 1992; 267: 11455-11461.
6. Yan H, Du J, Tang C. The possible role of hydrogen sulfide on the pathogenesis of spontaneous hypertension in rats. Biochem Biophys Res Commun 2004; 313: 22-27.
7. Zhong G, Chen F, Cheng Y, Tang C, Du J. The role of hydrogen sulfide generation in the pathogenesis of hypertension in rats induced by inhibition of nitric oxide synthase. J Hypertens 2003; 21: 1879-1885.
8. Chunyu Z, Junbao D, Dingfang B, Hui Y, Xiuying T, Chaoshu T. The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats. Biochem Biophys Res Commun 2003; 302: 810-816.
9. 2S) content during septic shock and endotoxin shock in rats. J Infect 2003; 47: 155-160.
10. 2S generated by heart in rat and its effects on cardiac function. Biochem Biophys Res Commun 2004; 313: 362-368.
11. Geng B, Chang L, Pan C, Qi Y, Zhao J, Pang Y, et al. Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun 2004; 318: 756-763.
12. Wang J, Hegele RA. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH), Hum Genet 2003; 112: 404-408.
13. Wang J, Hegele RA. Genomic basis of cystathioninuria revealed by multiple mutations in cystathionine gamma-lyase (CTH). Hum Genet 2003; 112: 404-8.
14. Pace, NR. A molecular view of microbial diversity and the biosphere. Science 1997; 276: 734-740.
15. Stipanuk M H, Beck P W. Characterization of the enzymic capacity for cysteine desulphydration in liver and kidney of the rat. J Biochem 1982; 206: 267-277.
16. Abe K, Kimura H. The possible role of hydrogen sulfide as an endogenous neuromodulator. J Neurosci 1996; 16: 1066-1071.
17. Bukovska G, Kery V, Kraus JP. Expression of human cystathionine beta-synthase in Escherichia coli: purification and characterization. Protein Exp Purif 1994; 5: 442-448.
18. Erickson PF, Maxwell IH, Su LJ, Baumann M, Glode LM. Sequence of cDNA for rat cystathionine beta-lyase and comparison of deduced amino acid sequence with related Escherichia coli enzymes. J Biochem 1990; 269: 335-340.
19. Stipanuk M H, Beck P W. Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat. J Biochem 1982; 206: 267-277.
20. 2+ involvement. Immunopharmacol Immunotoxicol 1997; 19: 393-404.
21. Eto K, Ogasawara M, Umemura K, Nagai Y, Kimura H. Hydrogen sulfide is produced in response to neuronal excitation. J Neuro Sci 2002a, 22: 3386-3391.
22. Nagahara N, Ito T, Kitamura H, Nishino T. Tissue and subcellular distribution of mercaptopyruvate sulfurtransferase in the rat: confocal laser fluorescence and immunoelectron microscopic studies combined with biochemical analysis. Histochem Cell Biol 1998; 110: 243-250.
23. Kredich NM, Foote LJ, Keenen BS. The stoichiometry and kinetics of the inducible cysteine desulfhydrase from Salmonella typhimurium. J Biol Chem 1973; 248: 6187-6197.
24. Simpson RC, Freedland RA. Factors affecting the rate of gluconeogenesis from L-cysteine in the perfused rat liver. J Nutr 1976; 106: 1272-1278.
25. Searcy DG, Lee SH. Sulfur reduction by human erythrocytes. J Exp Zool 1998; 282: 310-322.
26. Westely AM, Westley J. Biological sulfane sulfur. Biochemistry1991; 195: 63-67.
27. Buzaleh AM, Vazquez ES, Carmen B. Cyanide intoxication - III. On the analogous and different effects provoked by non-lethal and lethal challenged doses. Gen Pharmacol 1990; 21: 27-32.
28. Bartholomew TC, Powell GM, Dodgson KS, Curtis CG. Oxidation of sodium sulphide by rat liver, lungs and kidney. Biochem Pharmacol 1980; 29: 2431-2433.
29. Ubuka T, Yuasa S, Ohta J, Masuoka N, Yao K, Kinuta M. Formation of sulfate from L-cysteine in rat liver mitochondria. Acta Med Okayama 1990; 44: 55-64.
30. Ubuka T, Ohta J, Yao WB, Abe T, Teraoka T, Kurozumi Y. L-cysteine metabolism in a 3-mercaptopyruvate pathway and sulfate formation in rat liver mitochondria. Amino Acids 1992; 2: 143-155
31. Huang J, Khan S, O'Brien PJ. The glutathione dependence of inorganic sulfate formation from L-or D-cysteine in isolated rat hepatocytes. Chem Biol Interact 1998; 110: 189-202.
32. Ubuka T, Ohta J, Yao WB, Abe T, Teraoka T, Kurozumi Y. L-cysteine metabolism in a 3-mercaptopyruvate pathway and sulfate formation in rat liver mitochondria. Amino Acids 1992; 2: 143-155.
33. Guidotti TL. Hydrogen sulphide. Occup Med (Lond) 1996; 46; 367-371.
34. Kilburn KH, Warshaw RH. Hydrogen sulfide and reduced-sulfur gases adversely affect neurophysiological functions. Toxicol Ind Health 1995; 11: 185-197.
35. Whiteman M, Armstrong JS, Chu SH, Jia Ling S, Wong BS, Cheung NS, Halliwell B, Moore PK. The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? J Neurochem 2004; 90: 765-768.
36. Eto K, Ogasawara M, Umemura K, Nagai Y, Kimura H. Hydrogen sulfide is produced in response to neuronal excitation. J Neurosci 2002; 22: 3386-91.
37. Roth SH, Skrajny B, Reiffenstein RJ. Alteration of the morphology and neurochemistry of the developing mammalian nervous system by hydrogen sulphide. Clin Exp Pharmacol Physiol 1995; 22: 379-380.
38. Skrajny B, Hannah RS, Roth SH. Low concentrations of hydrogen sulphide alter monoamine levels in the developing rat central nervous system. Can J Physiol Pharmacol 1992; 70: 1515-1518.
39. Reiffenstein RJ, Hulbert WC, Roth SH. Toxicology of hydrogen sulfide. Annu Rev Pharmacol Toxicol 1992; 32109-32134.
40. Hannah RS, Roth SH. Chronic exposure to low concentrations of hydrogen sulfide produces abnormal growth in developing cerebellar Purkinje cells. Neurosci Lett 1991; 122: 225-228.
41. Eto K, Kimura H. The production of hydrogen sulfide is regulated by testosterone and S-adenosyl-l-methionine in mouse brain. J Neurochem 2002; 83: 80-86.
42. Eto K, Asada T, Arima K, Makifuchi T, Kimura H. Brain hydrogen sulfide is severely decreased in Alzheimer's disease. Biochem Biophys Res Commun 2002; 293: 1485-1488.
43. Kamoun P, Belardinelli MC, Chabli A, Lallouchi K, Chadefaux-Vekemans B. Endogenous hydrogen sulfide overproduction in Down syndrome. Am J Med Genet 2003; 116A: 310-311.
44. Deplancke B, Gaskins HR. Hydrogen sulfide induces serum-independent cell cycle entry in nontransformed rat intestinal epithelial cells. FASEB J 2003; 17: 1310-1312.
45. Suarez F, Furne J, Springfield J, Levitt M. Production and elimination of sulfur-containing gases in the rat colon. Am J Physiol 1998; 274(4 Pt 1): G727-733.
46. Teague B, Asiedu S, Moore PK. The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility. Br J Pharmacol 2002; 137: 139-145.
47. ATP channel opener. J EMBO 2001; 20: 6008-6016.
48. Hosoki R, Matsiki N, Kimura H. The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. Biochem Biophys Res Commun 1997; 237: 527-531.
49. 2S-induced vasorelaxation and underlying cellular and molecular mechanisms. Am J Physiol Heart Circ Physiol 2002; 283: H474-480.
50. Du J, Hui Y, Cheung Y, Bin G, Jiang H, Chen X, et al. The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells. Heart Vessels 2004; 19: 75-80.
51. 2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1. J Biol Chem 2004; 279: 49199-49205.
52. Yan H, Du J, Tang C. The influence of hydrogen sulfide on the proliferation and apoptosis of aorta smooth muscle cells in hypertension rats. J Appl Clin Pediatr 2004; 19: 188-190.
53. Chen X, Du J, Zhang C, Tang C, Zhou W. Effect of hydrogen sulfide, a new gaseous signal molecule, on pulmonary vascular smooth muscle cell apoptosis in rats. J Peking Univ (Health Sci) 2004; 36: 341-344.
54. Chen X, Du J, Zhang C, Tang C. The regulatory effect of hydrogen sulfide on pulmonary artery proliferating cell nuclear antigen and BcL-2 in hypoxic pulmonary rats. J Appl Clin Pediatr 2004; 19: 185-187.
55. Shi L, Du J, Qi J, Wei B, Tang C. Effect of L-arginie on pathologic structure and endogenous hydrogen sulfide pathway in rats with pulmonary hypertension induced by high pulmonary blood flow. J Basic Med Sci Clin 2004; 24: 184-187.
56. McCully KS. Homocystinuria, arteriosclerosis, methylmalonic aciduria, and methyltransferase deficiency: a key case revisited. Nutr Rev 1992; 50: 7-12.
57. 2S be the third endogenous gaseous transmitter? FASEB J 2002; 16: 1792-1798.
58. Zhang Q, Du J, Shi L, Zhang C, Yan H, Tang C. Interaction between endogenous nitric oxide and hydrogen sulfide in pathogenesis of hypoxic pulmonary hypertension. J Peking Univ (Health Sci) 2004; 36: 52-56.
59. Qingyou Z, Junbao D, Weijin Z, Hui Y, Chaoshu T, Chunyu Z. Impact of hydrogen sulfide on carbon monoxide/heme oxygenase pathway in the pathogenesis of hypoxic pulmonary hypertension. Biochem Biophys Res Commun 2004; 317: 30-37.