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Volumn 21, Issue 3, 2006, Pages 579-581

Immune therapy of lupus: What is on the horizon?

Author keywords

Anti cytokine; Immunotherapy; Lupus nephritis; Monoclonal antibodies; Treatment

Indexed keywords

ABATACEPT; ABETIMUS; B7 ANTIGEN; BELIMUMAB; CD28 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CD40 LIGAND MONOCLONAL ANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EPRATUZUMAB; GAMMA INTERFERON; IDEC 131; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 18; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; RITUXIMAB; TUMOR NECROSIS FACTOR;

EID: 33644866316     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfi282     Document Type: Editorial
Times cited : (4)

References (37)
  • 1
    • 0037668545 scopus 로고    scopus 로고
    • Pathogenesis of systemic lupus erythematosus
    • Mok CC, Lau CS. Pathogenesis of systemic lupus erythematosus. J Clin Pathol 2003; 56: 481-490
    • (2003) J Clin Pathol , vol.56 , pp. 481-490
    • Mok, C.C.1    Lau, C.S.2
  • 2
    • 15944409246 scopus 로고    scopus 로고
    • Theory, targets and therapy in systemic lupus erythematosus
    • Vasoo S, Hughes GRV. Theory, targets and therapy in systemic lupus erythematosus. Lupus 2005; 14: 181-188
    • (2005) Lupus , vol.14 , pp. 181-188
    • Vasoo, S.1    Hughes, G.R.V.2
  • 3
    • 13444266045 scopus 로고    scopus 로고
    • Cytokine expression in lupus kidneys
    • Aringer M, Smolen JS. Cytokine expression in lupus kidneys. Lupus 2005; 14: 13-18
    • (2005) Lupus , vol.14 , pp. 13-18
    • Aringer, M.1    Smolen, J.S.2
  • 4
    • 0023732974 scopus 로고
    • Increased tumor necrosis factor and IL-1 beta gene expression in the kidneys of mice with lupus nephritis
    • Boswell JM, Yui MA, Burt DW, Kelley VE. Increased tumor necrosis factor and IL-1 beta gene expression in the kidneys of mice with lupus nephritis. J Immunol 1988; 141: 3050-3054
    • (1988) J Immunol , vol.141 , pp. 3050-3054
    • Boswell, J.M.1    Yui, M.A.2    Burt, D.W.3    Kelley, V.E.4
  • 5
    • 0029020289 scopus 로고
    • Presence of tumor necrosis factor-alpha and interleukin-6 in renal mesangial cells of lupus nephritis patients
    • Malide D, Russo P. Bendayan M. Presence of tumor necrosis factor-alpha and interleukin-6 in renal mesangial cells of lupus nephritis patients. Hum Pathol 1995; 26: 558-564
    • (1995) Hum Pathol , vol.26 , pp. 558-564
    • Malide, D.1    Russo, P.2    Bendayan, M.3
  • 6
    • 0029955420 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha and its soluble receptors parallel clinical disease and autoimmune activity in systemic lupus erythematosus
    • Studnicka-Benke A, Steiner G, Petera P, Smolen JS. Tumour necrosis factor alpha and its soluble receptors parallel clinical disease and autoimmune activity in systemic lupus erythematosus. Br J Rheumatol 1996; 35: 1067-1074
    • (1996) Br J Rheumatol , vol.35 , pp. 1067-1074
    • Studnicka-Benke, A.1    Steiner, G.2    Petera, P.3    Smolen, J.S.4
  • 7
    • 5644258326 scopus 로고    scopus 로고
    • Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: An open label study
    • Aringer M, Graninger WB, Steiner G, Smolen JS. Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: An open label study. Arthritis Rheum 2004; 50: 3161-3169
    • (2004) Arthritis Rheum , vol.50 , pp. 3161-3169
    • Aringer, M.1    Graninger, W.B.2    Steiner, G.3    Smolen, J.S.4
  • 8
    • 0036846099 scopus 로고    scopus 로고
    • Correlation of renal tubular epithelial cell-derived interleukin-18 upregulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis
    • Faust J, Menke J, Kriegsmann J et al. Correlation of renal tubular epithelial cell-derived interleukin-18 upregulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis. Arthritis Rheum 2002; 46: 3083-3095
    • (2002) Arthritis Rheum , vol.46 , pp. 3083-3095
    • Faust, J.1    Menke, J.2    Kriegsmann, J.3
  • 9
    • 2942709722 scopus 로고    scopus 로고
    • Targeting interferon-alpha in SLE therapy
    • Schmidt KN, Ouyang W. Targeting interferon-alpha in SLE therapy. Lupus 2004; 13: 348-352
    • (2004) Lupus , vol.13 , pp. 348-352
    • Schmidt, K.N.1    Ouyang, W.2
  • 10
    • 0037451124 scopus 로고    scopus 로고
    • Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice
    • Santiago-Raber ML, Baccala R, Haraldsson KN et al. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J Exp Med 2003; 197: 777-788
    • (2003) J Exp Med , vol.197 , pp. 777-788
    • Santiago-Raber, M.L.1    Baccala, R.2    Haraldsson, K.N.3
  • 11
    • 0031861643 scopus 로고    scopus 로고
    • IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice
    • Mihara M, Takagi N, Takeda Y, Obsugi Y. IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice. Clin Exp Rheumatol 1998; 112: 397-402
    • (1998) Clin Exp Rheumatol , vol.112 , pp. 397-402
    • Mihara, M.1    Takagi, N.2    Takeda, Y.3    Obsugi, Y.4
  • 12
    • 2942752122 scopus 로고    scopus 로고
    • Rationale for interleukin-6 blockade in systemic lupus erythematosus
    • Tackey E. Lipsky PE, Illei G. Rationale for interleukin-6 blockade in systemic lupus erythematosus. Lupus 2004; 13: 339-343
    • (2004) Lupus , vol.13 , pp. 339-343
    • Tackey, E.1    Lipsky, P.E.2    Illei, G.3
  • 13
    • 0031961344 scopus 로고    scopus 로고
    • Elevated IL-10 levels correlated with disease activity in systemic lupus erythematosus
    • Park Y. Lee SK, Kim DS et al. Elevated IL-10 levels correlated with disease activity in systemic lupus erythematosus. Clin Exp Rheumatol 1998; 16: 283-288
    • (1998) Clin Exp Rheumatol , vol.16 , pp. 283-288
    • Park, Y.1    Lee, S.K.2    Kim, D.S.3
  • 14
    • 0033883903 scopus 로고    scopus 로고
    • Clinical and biologic effects of anti-interleukin 10 monoclonal antibody administration in systemic lupus erythematosus
    • Llorente L, Richard-Patin Y, Garcia-Padilla C et al. Clinical and biologic effects of anti-interleukin 10 monoclonal antibody administration in systemic lupus erythematosus. Arthritis Rheum 2000; 43: 1790-1800
    • (2000) Arthritis Rheum , vol.43 , pp. 1790-1800
    • Llorente, L.1    Richard-Patin, Y.2    Garcia-Padilla, C.3
  • 15
    • 4344624041 scopus 로고    scopus 로고
    • B cells in human and murine systemic lupus erythematosus
    • Anolik J, Sanz I. B cells in human and murine systemic lupus erythematosus. Curr Opin Rheumatol 2004; 16: 505-512
    • (2004) Curr Opin Rheumatol , vol.16 , pp. 505-512
    • Anolik, J.1    Sanz, I.2
  • 16
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • Chan OT, Hannum LG, Haberman AM et al. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 1999; 189: 1639-1648
    • (1999) J Exp Med , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3
  • 17
    • 0028204119 scopus 로고
    • B cells process and present lupus autoantigens that initiate autoimmune T cell responses
    • Mamula MJ, Fatenejad S, Craft J. B cells process and present lupus autoantigens that initiate autoimmune T cell responses. J Immunol 1994; 152: 1453-1461
    • (1994) J Immunol , vol.152 , pp. 1453-1461
    • Mamula, M.J.1    Fatenejad, S.2    Craft, J.3
  • 18
    • 4043179907 scopus 로고    scopus 로고
    • B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I/II dose-escalation trial of rituximab
    • Looney RJ, Anolik JH, Campbell D et al. B cell depletion as a novel treatment for systemic lupus erythematosus: A phase I/II dose-escalation trial of rituximab. Arthritis Rheum 2004; 50: 2580-2589
    • (2004) Arthritis Rheum , vol.50 , pp. 2580-2589
    • Looney, R.J.1    Anolik, J.H.2    Campbell, D.3
  • 19
    • 0036822286 scopus 로고    scopus 로고
    • An open study of B lymphocyte depletion in systemic lupus erythematosus
    • Leandro MJ, Edwards JC, Cambridge G et al. An open study of B lymphocyte depletion in systemic lupus erythematosus. Arthritis Rheum 2002; 46: 2673-2677
    • (2002) Arthritis Rheum , vol.46 , pp. 2673-2677
    • Leandro, M.J.1    Edwards, J.C.2    Cambridge, G.3
  • 20
    • 13444258270 scopus 로고    scopus 로고
    • Treatment of refractory lupus nephritis with B lymphocyte depletion
    • Leandro MJ, Ehrenstein MR, Edwards JC et al. Treatment of refractory lupus nephritis with B lymphocyte depletion. Arthritis Rheum 2003; 48: S594
    • (2003) Arthritis Rheum , vol.48
    • Leandro, M.J.1    Ehrenstein, M.R.2    Edwards, J.C.3
  • 21
    • 1942441554 scopus 로고    scopus 로고
    • An open study of B cell depletion in patients with proliferative lupus nephritis: Preliminary results
    • Boletis JN, Sfikakis PP, Lionaki SJ et al. An open study of B cell depletion in patients with proliferative lupus nephritis: Preliminary results. J Am Soc Nephrol 2003; 14: 379
    • (2003) J Am Soc Nephrol , vol.14 , pp. 379
    • Boletis, J.N.1    Sfikakis, P.P.2    Lionaki, S.J.3
  • 22
    • 8444223507 scopus 로고    scopus 로고
    • Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus
    • Anolik JH, Barnard J, Cappione A et al. Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus. Arthritis Rheum 2004; 50: 3580-3590
    • (2004) Arthritis Rheum , vol.50 , pp. 3580-3590
    • Anolik, J.H.1    Barnard, J.2    Cappione, A.3
  • 23
    • 13444283464 scopus 로고    scopus 로고
    • Novel therapies in lupus nephritis
    • Tahir H, Isenberg DA. Novel therapies in lupus nephritis. Lupus 2005; 14: 77-82
    • (2005) Lupus , vol.14 , pp. 77-82
    • Tahir, H.1    Isenberg, D.A.2
  • 24
    • 24344507491 scopus 로고    scopus 로고
    • Initial clinical study of immunotherapy in SLE using epratuzumab (humanized anti-CD22 antibody)
    • Kaufmann J, Wegener WA, Horak ID et al. Initial clinical study of immunotherapy in SLE using epratuzumab (humanized anti-CD22 antibody). Arthritis Rheum 2004; 50: S447
    • (2004) Arthritis Rheum , vol.50
    • Kaufmann, J.1    Wegener, W.A.2    Horak, I.D.3
  • 25
    • 0029073665 scopus 로고
    • Immunospecific reduction of antioligonucleotide antibody forming cells with a tetrakis-oligonucleotide conjugate (LJP-394), a therapeutic candidate for the treatment of lupus nephritis
    • Jones DS, Barstad PA, Field MJ et al. Immunospecific reduction of antioligonucleotide antibody forming cells with a tetrakis-oligonucleotide conjugate (LJP-394), a therapeutic candidate for the treatment of lupus nephritis. J Med Chem 1995; 38: 2138-2144
    • (1995) J Med Chem , vol.38 , pp. 2138-2144
    • Jones, D.S.1    Barstad, P.A.2    Field, M.J.3
  • 26
    • 0031055675 scopus 로고    scopus 로고
    • Reduction in circulating dsDNA antibody titre after administration of LJP-394
    • Weisman MH, Bluestein HG, Berner CM et al. Reduction in circulating dsDNA antibody titre after administration of LJP-394. J Rheumatol 1997; 24: 314-318
    • (1997) J Rheumatol , vol.24 , pp. 314-318
    • Weisman, M.H.1    Bluestein, H.G.2    Berner, C.M.3
  • 27
    • 0037331980 scopus 로고    scopus 로고
    • LJP-394 for the prevention of renal flare in patients with systemic lupus erythematosus
    • Alarcon-Segovia D, Tumlin JA, Furie RA et al. LJP-394 for the prevention of renal flare in patients with systemic lupus erythematosus. Arthritis Rheum 2003; 48: 442-454
    • (2003) Arthritis Rheum , vol.48 , pp. 442-454
    • Alarcon-Segovia, D.1    Tumlin, J.A.2    Furie, R.A.3
  • 28
    • 0035167632 scopus 로고    scopus 로고
    • Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus
    • Zhang J, Roschke V, Baker KP et al. Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus. J Immunol 2001; 166: 6-10
    • (2001) J Immunol , vol.166 , pp. 6-10
    • Zhang, J.1    Roschke, V.2    Baker, K.P.3
  • 29
    • 10744224617 scopus 로고    scopus 로고
    • B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: Longitudinal observations
    • Stohl W, Metyas S, Tan SM et al. B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: Longitudinal observations. Arthritis Rheum 2003; 48: 3475-3486
    • (2003) Arthritis Rheum , vol.48 , pp. 3475-3486
    • Stohl, W.1    Metyas, S.2    Tan, S.M.3
  • 30
    • 0346026830 scopus 로고    scopus 로고
    • Safety, pharmacokinetic and pharmacodynamic results of a phase I single and double dose-escalation study of lymphostat-B (human monoclonal antibody to BLyS) in SLE patients
    • Furie R, Stohl W, Ginzler E et al. Safety, pharmacokinetic and pharmacodynamic results of a phase I single and double dose-escalation study of lymphostat-B (human monoclonal antibody to BLyS) in SLE patients. Arthritis Rheum 2003; 48: S377
    • (2003) Arthritis Rheum , vol.48
    • Furie, R.1    Stohl, W.2    Ginzler, E.3
  • 31
    • 1242272832 scopus 로고    scopus 로고
    • Costimulatory molecules and T cell-B cell interactions
    • Crow M. Costimulatory molecules and T cell-B cell interactions. Rheum Dis Clin N Am 2004; 30: 175-192
    • (2004) Rheum Dis Clin N Am , vol.30 , pp. 175-192
    • Crow, M.1
  • 32
    • 0037332140 scopus 로고    scopus 로고
    • Effects of anti-CD154 treatment on B cells in murine systemic lupus erythematosus
    • Wang X, Huang W, Schiffer LE et al. Effects of anti-CD154 treatment on B cells in murine systemic lupus erythematosus. Arthritis Rheum 2003; 48: 495-506
    • (2003) Arthritis Rheum , vol.48 , pp. 495-506
    • Wang, X.1    Huang, W.2    Schiffer, L.E.3
  • 33
    • 0036899589 scopus 로고    scopus 로고
    • Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: A randomized, double-blind, placebo-controlled trial
    • Kalunian KC, Davis Jr. JC, Merrill JT et al. Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: A randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002; 46: 3251-3258
    • (2002) Arthritis Rheum , vol.46 , pp. 3251-3258
    • Kalunian, K.C.1    Davis Jr., J.C.2    Merrill, J.T.3
  • 34
    • 0037333857 scopus 로고    scopus 로고
    • A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis
    • Boumpas DT, Furie R, Manzi S et al. A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis. Arthritis Rheum 2003; 48: 719-727
    • (2003) Arthritis Rheum , vol.48 , pp. 719-727
    • Boumpas, D.T.1    Furie, R.2    Manzi, S.3
  • 35
    • 0034101827 scopus 로고    scopus 로고
    • CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis
    • Reynolds J, Tam FW, Chandraker A et al. CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis. J Clin Invest 2000; 105: 643-651
    • (2000) J Clin Invest , vol.105 , pp. 643-651
    • Reynolds, J.1    Tam, F.W.2    Chandraker, A.3
  • 36
    • 0000052398 scopus 로고    scopus 로고
    • Reversal of advanced murine lupus nephritis with combined CTLA4Ig and cyclophosphamide
    • Daikh DI, Wofsky D. Reversal of advanced murine lupus nephritis with combined CTLA4Ig and cyclophosphamide. Arthritis Rheum 1996; 39: S140
    • (1996) Arthritis Rheum , vol.39
    • Daikh, D.I.1    Wofsky, D.2
  • 37
    • 21644468434 scopus 로고    scopus 로고
    • The evolving clinical profile of abatacept (CTLA4-Ig): A novel co-stimulatory modulator for the treatment of rheumatoid arthritis
    • Ruderman EM, Pope RM. The evolving clinical profile of abatacept (CTLA4-Ig): A novel co-stimulatory modulator for the treatment of rheumatoid arthritis. Arthritis Res Ther 2005; 7 [Suppl 2]: S21-S25
    • (2005) Arthritis Res Ther , vol.7 , Issue.SUPPL. 2
    • Ruderman, E.M.1    Pope, R.M.2


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