Wiedemann-Rautenstrauch syndrome's fibroblasts display a normal in vitro lifespan [8]

American Journal of Medical Genetics

Volumn 140 A, Issue 6, 2006, Pages 661-662

  Nowak, Radosława ^a   Sawadro Rochowska, Maria ^a   Siwicki, Jan K ^a   Korniszewski, Lech ^b  

^a INSTITUTE OF ONCOLOGY   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE;

ATAXIA TELANGIECTASIA; CELL AGING; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; LETTER; PATHOGENESIS; PRIORITY JOURNAL; PROGERIA; SKIN FIBROBLAST; SYNDROME; TELOMERE; WERNER SYNDROME; WIEDEMANN RAUTENSTRAUCH SYNDROME;

CELL AGING; CELL DIVISION; FIBROBLASTS; HUMANS; INFANT, NEWBORN; PROGERIA; SYNDROME; TELOMERE;

ATAXIA TELANGIECTASIA;

EID: 33644860182     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.31128     Document Type: Letter

References (9)

1. Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW, Harley CB. 1992. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 89:10114-10118.
2. Baird DM, Davis T, Rowson J, Jones CJ, Kipling D. 2004. Normal telomere erosion rates at the single cell level in Werner syndrome fibroblats cells. Hum Mol Genet 13:1515-1524.
3. Ben-Porath I, Weinberg RA. 2005. The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 37:961-976.
4. Cristofalo VJ, Allen RG, Pignolo RJ, Martin BG, Beck JC. 1998. Relationship between donor age and the replicative lifespan of human cells in culture: A reevaluation. Proc Natl Acad Sci USA 95:10614-10619.
5. Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubeli I, Pereira-Smith O, Peacocke M, Campisi J. 1995. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92:9363-9367.
6. Jaeger M, Thorey F, Westhoff B, Wild A, Krauspe R. 2005. In vitro osteogenic differentiation is affected in Wiedemann-Rautenstrauch-syndrome (WRS). In vivo 19:831-836.
7. Korniszewski L, Nowak R, Okninska-Hoffmann E, Skorka A, Gieruszczak-Bialek D, Sawadro-Rochowska M. 2001. Wiedemann-Rautenstrauch (neonatal progeroid) syndrome: New case with normal telomere length in skin fibroblasts. Am J Med Genet 103:144-148.
8. Schulz VP, Zakian VA, Ogburn CE, McKay J, Jarzebowicz AA, Edland SD, Martin GM. 1996. Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells. Hum Genet 97:750-754.
9. Vaziri H, West MD, Allsopp RC, Davison TS, Wu YS, Arrowsmith CH, Poirier GG, Benchimol S. 1997. ATM-dependent telomere loss in aging human diploidal fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J 16:6018-6023.