Clinical efficacy of local administration of ceftiofur in a Staphylococcus aureus infection in tissue cages in ponies

Journal of Veterinary Pharmacology and Therapeutics

Volumn 29, Issue 1, 2006, Pages 31-36

  Bosch, G ^a   Van Duijkeren, E ^a   Bergwerff, A A ^a   Rijkenhuizen, A B M ^a   Ensink, J M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTIOFUR; CEPHALOSPORIN DERIVATIVE;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTHROSCOPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL COUNT; BLOOD SAMPLING; CONTROLLED STUDY; DRUG EFFICACY; EXPERIMENTAL INFECTION; HORSE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SOFT TISSUE INFECTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; ANIMAL; DRUG EFFECT; MALE; TREATMENT FAILURE;

ANIMALIA; BACTERIA (MICROORGANISMS); EQUIDAE; EQUUS CABALLUS; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

ANIMALS; CEPHALOSPORINS; HORSES; MALE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TREATMENT FAILURE;

EID: 33644856848     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2006.00706.x     Document Type: Article

References (25)

1. Adamson P.J. Wilson W.D. Hirsh D.C. Baggot J.D. Martin L.D. 1985 Susceptibility of equine bacterial isolates to antimicrobial agents. American Journal of Veterinary Research 46 447 450.
2. Beadle R.E. Short C.R. Corstvet R.E. Pawlusiow J. Nobles D.D. McClure J.R. Guthrie A.J. Clarke C.R. 1989 Characterization of a soft-tissue infection model in the horse and its response to intravenous cephapirin administration. Journal of Veterinary Pharmacology and Therapeutics 12 73 86.
3. Beconi-Barker M.G. Roof R.D. Millerioux L. Kausche F.M. Vidmar T.H. Smith E.B. Callahan J.K. Hubbard V.L. Smith G.A. Gilbertson T.J. 1995 Determination of ceftiofur and its desfuroylceftiofur-related metabolites in swine tissues by high-performance liquid chromatography. Journal of Chromatography. B, Biomedical Sciences and Applications 673 231 244.
4. Bertone A.L. McIlwraith C.W. Jones R.L. Norrdin R.W. Radin M.J. Lebel J.L. 1987 Comparison of various treatments for experimentally induced equine infectious arthritis. American Journal of Veterinary Research 48 519 529.
5. Bertone A.L. Davis D.M. Cox H.U. Kamerling S.S. Roberts E.D. Caprile K.A. Gossett K.A. 1992 Arthrotomy versus arthroscopy and partial synovectomy for treatment of experimentally induced infectious arthritis in horses. American Journal of Veterinary Research 53 585 591.
6. Brown S.A. Yancey J.R. Steffan J. 1991 Ceftiofur sodium: antimicrobial activity of parent ceftiofur and metabolites. Acta Veterinaria Scandinavica 87 95 97.
7. Clarke C.R. Short C.R. Corstvet R.E. Nobles D. 1989 Effect of Pasteurella haemolytica infection on the distribution of sulfadiazine and trimethoprim into tissue chambers implanted subcutaneously in cattle. American Journal of Veterinary Research 50 1551 1556.
8. Clarke C.R. Brown S.A. Streeter R.N. Clarke J.M. Hamlow P.J. Callahan J.K. Hubbard V.L. Speedy A.K. Burrows G.E. 1996 Penetration of parenterally administered ceftiofur into sterile vs. Pasteurella haemolytica-infected tissue chambers in cattle. Journal of Veterinary Pharmacology and Therapeutics 19 376 381.
9. Ensink J.M. Klein W.R. Barneveld A. Vulto A.G. van Miert A.S.J.P.A.M. 1996a Clinical efficacy of ampicillin, pivampicillin and procaine penicillin G in a soft tissue infection model in ponies. Journal of Veterinary Pharmacology and Therapeutics 19 445 453.
10. Ensink J.M. Klein W.R. Barneveld A. Vulto A.G. van Miert A.S.J.P.A.M. Tukker J.J. 1996b Distribution of penicillins into subcutaneous tissue chambers in ponies. Journal of Veterinary Pharmacology and Therapeutics 19 439 443.
11. Ensink J.M. Smit J.A.H. van Duijkeren E. 2003 Clinical efficacy of trimethoprim/sulfadiazine and procaine penicillin G in a Streptococcus equi subsp. zooepidemicus infection model in ponies. Journal of Veterinary Pharmacology and Therapeutics 26 247 252.
12. Ensink J.M. Bosch G. van Duijkeren E. 2005 Clinical efficacy of prophylactic administration of trimethoprim/sulfadiazine in a Streptococcus equi subsp. zooepidemicus infection model in ponies. Journal of Veterinary Pharmacology and Therapeutics 28 45 49.
13. Lloyd K.C. Stover S.M. Pascoe J.R. Adams P. 1990 Synovial fluid pH, cytologic characteristics, and gentamicin concentration after intra-articular administration of the drug in an experimental model of infectious arthritis in horses. American Journal of Veterinary Research 51 1363 1369.
14. Meijer M.C. van Weeren P.R. Rijkenhuizen A.B.M. 2000 Clinical experiences of treating septic arthritis in the equine by repeated joint lavage: a series of 39 cases. Journal of Veterinary Medicine 47 351 365.
15. Meyer J.C. Brown M.P. Gronwall R.R. Meritt K. 1992 Pharmacokinetics of ceftiofur sodium in neonatal foals after intramuscular injection. Equine Veterinary Journal 24 485 486.
16. Mills M.L. Rush B.R. St Jean G. Gaughan E.M. Mosier D. Gibson E. Freeman L. 2000 Determination of synovial fluid and serum concentrations, and morphologic effects of intra-articular ceftiofur sodium in horses. Veterinary Surgery 29 398 406.
17. Anonymous 2003 USP veterinary pharmaceutical information monographs - antibiotics. Journal of Veterinary Pharmacology and Therapeutics 26 54.
18. Okker H. Schmitt E.J. Vos P.L. Scherpenisse P. Bergwerff A.A. Jonker F.H. 2002 Pharmacokinetics of ceftiofur in plasma and uterine secretions and tissues after subcutaneous postpartum administration in lactating dairy cows. Journal of Veterinary Pharmacology and Therapeutics 25 33 38.
19. Olson M.E. Ceri H. Morck D.W. Buret A.G. Read R.R. 2002 Biofilm bacteria: formation and comparative susceptibility to antibiotics. Canadian Journal of Veterinary Research 66 86 92.
20. Prescott J.F. 2000 Beta-lactam antibiotics: cephalosporins and cephamycins. In Antimicrobial Therapy in Veterinary Medicine 3rd edn. Eds Prescott J.F. Baggot J.D. Walker R.D. 151 pp. Iowa State University Press Ames, Iowa, USA.q4
21. Salmon S.A. Watts J.L. Yancey R.J. Jr. 1996 In vitro activity of ceftiofur and its primary metabolite, desfuroylceftiofur, against organisms of veterinary importance. Journal of Veterinary Diagnostic Investigation 8 332 336.
22. Schneider R.K. Bramlage L.R. Mecklenburg L.M. Moore R.M. Gabel A.A. 1992a Open drainage, intra-articular and systemic antibiotics in the treatment of septic arthritis/tenosynovitis in horses. Equine Veterinary Journal 24 443 449.
23. Schneider R.K. Bramlage L.R. Moore R.M. Mecklenburg L.M. Kohn C.W. Gabel A.A. 1992b A retrospective study of 192 horses affected with septic arthritis/tenosynovitis. Equine Veterinary Journal 24 436 442.
24. Ter Braake F. 2002 Direct endoscopic approach improves prognosis of septic-synovitis in the horse. Tijdschrift voor Diergeneeskunde 127 444 449.
25. Tulamo R.M. Bramlage L.R. Gabel A.A. 1989 Sequential clinical and synovial fluid changes associated with acute infectious arthritis in the horse. Equine Veterinary Journal 21 325 331.