Clinical efficacy of ampicillin, pivampicillin and procaine penicillin G in a soft tissue infection model in ponies

Journal of Veterinary Pharmacology and Therapeutics

Volumn 19, Issue 6, 1996, Pages 445-453

  Ensink, J M ^a,b   Klein, W R ^a   Barneveld, A ^a   Vulto, A G ^a   Van Miert, A S J P A M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b Dept of Gen and Large Anim Surg ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; PIVAMPICILLIN; PROCAINE PENICILLIN;

ABSCESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; HORSE; IMPLANT; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SOFT TISSUE INFECTION; STREPTOCOCCUS; SUBCUTANEOUS TISSUE;

ANIMALIA; EQUUS CABALLUS; STREPTOCOCCUS; STREPTOCOCCUS EQUI SUBSP. ZOOEPIDEMICUS;

EID: 0030468341     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2885.1996.tb00081.x     Document Type: Article

References (14)

1. Beadle, R.E., Short, C.R., Corstvet, R.E. et. al. (1989) Characterization of a soft-tissue infection model in the horse and its response to intravenous cephapirin administration. Journal of Veterinary Pharmacoloay and Therapeutics, 12, 73-86.
2. Bertone, A.L., McIlwraith C.W., Jones, R.L., Norrdin, R.W., Radin, M.J. & Lebel, J.L. (1987) Comparison of various treatments for experimentally induced equine infectious arthritis. American Journal of Veterinary Research, 48, 519-529.
3. Brunton, J. (1984) Antibiotic resistance plasmids of Streptococci, Staphylococci and Bacteroides. In: Antimicrobial Drug Resistance. Ed. Bryan, L.E. Academic Press, Orlando.
4. Burke, J.E. (1961) The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery, 50, 161-168.
5. Ensink, J.M., Klein, W.R., Mevius, D.J., Klarenbeek, A. & Vulto, A.G. (1992) Bioavailability of oral penicillins in the horse: a comparison of pivampicillin and amoxicillin. Journal of Veterinary Pharmacology and Therapeutics, 15, 221-230.
6. Ensink J.M., van Klingeren, B., Houwers, D.J., Klein, W.R. & Vulto, A.G. (1993) In vitro susceptibility to antimicrobial drugs of bacterial isolates from horses in the Netherlands. Equine Veterinary Journal, 25, 309-313.
7. Ensink, J.M., Klein, W.R., Barneveld, A., Vulto, A.G., van Miert, A.S.J.P.A.M. & Tukker, J.J. (1996) Distribution of penicillins into subcutaneous tissue chambers in ponies. Journal of Veterinary Pharmacology and Therapeutics, 19, 438-443.
8. Fink-Gremmels, J. & van Miert, A.S.J.P.A.M. (1994) Veterinary drugs: disposition, biotransformation and risk evaluation. Analyst, 119, 2521-2528.
9. Firth, E.C., Klein, W.R., Nouws, J.F.M. & Wensing, Th. (1988) Effect of induced synovial inflammation on pharmacokinetics and synovial concentration of sodium ampicillin and kanamycin sulfate after systemic administration in ponies. Journal of Veterinary Pharmacology and Therapeutics, 11, 56-62.
10. Love, D.N., Rose, R.J., Martin, C.A. & Bailey, M. (1984) Serum concentrations of penicillin in the horse after administration of a variety of penicillin preparations. Equine Veterinary Journal, 15, 43-48.
11. Mouton, R.P. & van Klingeren B. (1985) The standardisation of Susceptibility Tests. Report of the Working Party on Guidelines for Susceptibility Testing (in Dutch). National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
12. Parr T.R. & Bryan L.E. (1984) Nonenzymatic resistance to β-lactam antibiotics. In: Antimicrobial Drug Resistance. Ed. Bryan, L.E. Academic Press, Orlando.
13. Varma, K.J., Powers, T.E., Garg, R.C., Spurlock, S.L. & Powers, J.D. (1982) Efficacy of penicillin against Streptococcus zooepidemicus infection model in the horse. Proc. of the Second International Congress of the European Association for Veterinary Pharmacology and Toxicology pp. 429-435.
14. Woolcock, J.B. & Mutimer, M.D. (1983) Antibiotic susceptibility testing: caeci caecos ducentes? The Veterinary Record, 113, 125-128.