-
1
-
-
0018345066
-
Muscle fiber characteristics in healthy men and patients with juvenile diabetes
-
Saltin B, Houston M, Nygaard E, Graham T, Wahren J: Muscle fiber characteristics in healthy men and patients with juvenile diabetes. Diabetes 28 (Suppl 1):93-99, 1979
-
(1979)
Diabetes
, vol.28
, Issue.1 SUPPL.
, pp. 93-99
-
-
Saltin, B.1
Houston, M.2
Nygaard, E.3
Graham, T.4
Wahren, J.5
-
2
-
-
0021268588
-
Studies on the mechanism of improved glucose control during regular exercise in type 2 (noninsulin-dependent) diabetes
-
Schneider SH, Amorosa LF, Khachadurian AK, Ruderman NB: Studies on the mechanism of improved glucose control during regular exercise in type 2 (noninsulin-dependent) diabetes. Diabetologia 26:355-360, 1984
-
(1984)
Diabetologia
, vol.26
, pp. 355-360
-
-
Schneider, S.H.1
Amorosa, L.F.2
Khachadurian, A.K.3
Ruderman, N.B.4
-
3
-
-
33644614096
-
Rosiglitazone improves exercise capacity in individuals with type 2 diabetes
-
Regensteiner JG, Bauer TA, Reusch JEB: Rosiglitazone improves exercise capacity in individuals with type 2 diabetes. Diabetes Care 28:2877-2883, 2005
-
(2005)
Diabetes Care
, vol.28
, pp. 2877-2883
-
-
Regensteiner, J.G.1
Bauer, T.A.2
Reusch, J.E.B.3
-
4
-
-
0035083645
-
Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity
-
He J, Watkins S, Kelley DE: Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity. Diabetes 50:817-823, 2001
-
(2001)
Diabetes
, vol.50
, pp. 817-823
-
-
He, J.1
Watkins, S.2
Kelley, D.E.3
-
5
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB: Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51:2944-2950, 2002
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
6
-
-
12144275294
-
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
-
Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE: Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 54:8-14, 2005
-
(2005)
Diabetes
, vol.54
, pp. 8-14
-
-
Ritov, V.B.1
Menshikova, E.V.2
He, J.3
Ferrell, R.E.4
Goodpaster, B.H.5
Kelley, D.E.6
-
7
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately down-regulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstrale M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC: PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately down-regulated in human diabetes. Nat Genet 34:267-273, 2003
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
Subramanian, A.4
Sihag, S.5
Lehar, J.6
Puigserver, P.7
Carlsson, E.8
Ridderstrale, M.9
Laurila, E.10
Houstis, N.11
Daly, M.J.12
Patterson, N.13
Mesirov, J.P.14
Golub, T.R.15
Tamayo, P.16
Spiegelman, B.17
Lander, E.S.18
Hirschhorn, J.N.19
Altshuler, D.20
Groop, L.C.21
more..
-
8
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ: Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A 100:8466-8471, 2003
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
DeFronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
9
-
-
0032485927
-
Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo
-
Williams SB, Goldfine AB, Timimi FK, Ting HH, Roddy M-A, Simonson DC, Creager MA: Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo. Circulation 97:1695-1701, 1998
-
(1998)
Circulation
, vol.97
, pp. 1695-1701
-
-
Williams, S.B.1
Goldfine, A.B.2
Timimi, F.K.3
Ting, H.H.4
Roddy, M.-A.5
Simonson, D.C.6
Creager, M.A.7
-
10
-
-
0029977757
-
Obesity/insulin resistance is associated with endothelial dysfunction: Implications for the syndrome of insulin resistance
-
Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD: Obesity/insulin resistance is associated with endothelial dysfunction: implications for the syndrome of insulin resistance. J Clin Invest 97:2601-2610, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 2601-2610
-
-
Steinberg, H.O.1
Chaker, H.2
Leaming, R.3
Johnson, A.4
Brechtel, G.5
Baron, A.D.6
-
11
-
-
0034043652
-
Nutritive and non-nutritive blood flow: Rest and exercise
-
Clark MG, Rattigan S, Clerk LH, Vincent MA, Clark AD, Youd JM, Newman JM: Nutritive and non-nutritive blood flow: rest and exercise. Acta Physiol Scand 168:519-530, 2000
-
(2000)
Acta Physiol Scand
, vol.168
, pp. 519-530
-
-
Clark, M.G.1
Rattigan, S.2
Clerk, L.H.3
Vincent, M.A.4
Clark, A.D.5
Youd, J.M.6
Newman, J.M.7
-
12
-
-
0030747895
-
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: No alteration in adipose tissue of obese and NIDDM patients
-
Auboeuf D, Rieusset J, Fajas L, Vallier P, Frering V, Riou JP, Staels B, Auwerx J, Laville M, Vidal H: Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 46:1319-1327, 1997
-
(1997)
Diabetes
, vol.46
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Auwerx, J.8
Laville, M.9
Vidal, H.10
-
13
-
-
0036182137
-
Lipotoxic diseases
-
Unger RH: Lipotoxic diseases. Annu Rev Med 53:319-336, 2002
-
(2002)
Annu Rev Med
, vol.53
, pp. 319-336
-
-
Unger, R.H.1
-
14
-
-
0042330251
-
Minireview: The adipocyte: At the crossroads of energy homeostasis, inflammation, and atherosclerosis
-
Rajala MW, Scherer PE: Minireview: the adipocyte: at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 144:3765-3773, 2003
-
(2003)
Endocrinology
, vol.144
, pp. 3765-3773
-
-
Rajala, M.W.1
Scherer, P.E.2
-
15
-
-
3843061592
-
AMP kinase and malonyl-CoA: Targets for therapy of the metabolic syndrome
-
Ruderman N, Prentki M: AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nat Rev Drug Discov 3:340-351, 2004
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 340-351
-
-
Ruderman, N.1
Prentki, M.2
-
16
-
-
0036789137
-
The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
-
Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, Olefsky JM: The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51:2968-2974, 2002
-
(2002)
Diabetes
, vol.51
, pp. 2968-2974
-
-
Yu, J.G.1
Javorschi, S.2
Hevener, A.L.3
Kruszynska, Y.T.4
Norman, R.A.5
Sinha, M.6
Olefsky, J.M.7
-
17
-
-
0242581695
-
Adiponectin stimulates production of nitric oxide in vascular endothelial cells
-
Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ: Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 278:45021-45026, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 45021-45026
-
-
Chen, H.1
Montagnani, M.2
Funahashi, T.3
Shimomura, I.4
Quon, M.J.5
-
18
-
-
0037020170
-
Role of adiponectin in preventing vascular stenosis: The missing link of adipo-vascular axis
-
Matsuda M, Shimomura I, Sata M, Arita Y, Nishida M, Maeda N, Kumada M, Okamoto Y, Nagaretani H, Nishizawa H, Kishida K, Komuro R, Ouchi N, Kihara S, Nagai R, Funahashi T, Matsuzawa Y: Role of adiponectin in preventing vascular stenosis: the missing link of adipo-vascular axis. J Biol Chem 277:37487-37491, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 37487-37491
-
-
Matsuda, M.1
Shimomura, I.2
Sata, M.3
Arita, Y.4
Nishida, M.5
Maeda, N.6
Kumada, M.7
Okamoto, Y.8
Nagaretani, H.9
Nishizawa, H.10
Kishida, K.11
Komuro, R.12
Ouchi, N.13
Kihara, S.14
Nagai, R.15
Funahashi, T.16
Matsuzawa, Y.17
-
19
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF: Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci U S A 98:2005-2010, 2001
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
Tsao, T.S.2
Javorschi, S.3
Ebbets-Reed, D.4
Erickson, M.R.5
Yen, F.T.6
Bihain, B.E.7
Lodish, H.F.8
-
20
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ: The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 112:91-100, 2003
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
21
-
-
0037059013
-
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation
-
Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang Cc C, Itani SI, Lodish HF, Ruderman NB: Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci U S A 99:16309-16313, 2002
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16309-16313
-
-
Tomas, E.1
Tsao, T.S.2
Saha, A.K.3
Murrey, H.E.4
Zhang, Cc.C.5
Itani, S.I.6
Lodish, H.F.7
Ruderman, N.B.8
-
22
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, Yamashita S, Noda M, Kita S, Ueki K, Eto K, Akanuma Y, Froguel P, Foufelle F, Ferre P, Carling D, Kimura S, Nagai R, Kahn BB, Kadowaki T: Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8:1288-1295, 2002
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
23
-
-
2942748585
-
Metabolic and hormonal interactions between muscle and adipose tissue
-
Tomas E, Kelly M, Xiang X, Tsao TS, Keller C, Keller P, Luo Z, Lodish H, Saha AK, Unger R, Ruderman NB: Metabolic and hormonal interactions between muscle and adipose tissue. Proc Nutr Soc 63:381-385, 2004
-
(2004)
Proc Nutr Soc
, vol.63
, pp. 381-385
-
-
Tomas, E.1
Kelly, M.2
Xiang, X.3
Tsao, T.S.4
Keller, C.5
Keller, P.6
Luo, Z.7
Lodish, H.8
Saha, A.K.9
Unger, R.10
Ruderman, N.B.11
-
24
-
-
0037067666
-
The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
-
Fryer LG, Parbu-Patel A, Carling D: The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J Biol Chem 277:25226-25232, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 25226-25232
-
-
Fryer, L.G.1
Parbu-Patel, A.2
Carling, D.3
-
25
-
-
2942748289
-
AMPK activity is diminished in tissues of IL-6 knockout mice: The effect of exercise
-
Kelly M, Keller C, Avilucea PR, Keller P, Luo Z, Xiang X, Giralt M, Hidalgo J, Saha AK, Pedersen BK, Ruderman NB: AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise. Biochem Biophys Res Commun 320:449-454, 2004
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 449-454
-
-
Kelly, M.1
Keller, C.2
Avilucea, P.R.3
Keller, P.4
Luo, Z.5
Xiang, X.6
Giralt, M.7
Hidalgo, J.8
Saha, A.K.9
Pedersen, B.K.10
Ruderman, N.B.11
-
26
-
-
12144271041
-
Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: Prevention of diabetes and ectopic lipid deposition
-
Yu X, McCorkle S, Wang M, Lee Y, Li J, Saha AK, Unger RH, Ruderman NB: Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition. Diabetologia 47:2012-2021, 2004
-
(2004)
Diabetologia
, vol.47
, pp. 2012-2021
-
-
Yu, X.1
McCorkle, S.2
Wang, M.3
Lee, Y.4
Li, J.5
Saha, A.K.6
Unger, R.H.7
Ruderman, N.B.8
|