Rapid and preferential distribution of blood-borne αCD3εAb to the liver is followed by local stimulation of T cells and natural killer T cells

Immunology

Volumn 117, Issue 1, 2006, Pages 117-126

  Wingender, Gerhard ^a   Schumak, Beatrix ^a   Schurich, Anna ^a   Gessner, J Engelbert ^b   Endl, Elmar ^a   Limmer, Andreas ^a   Knolle, Percy A ^a  

^a UNIVERSITY OF BONN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Fc receptor; Innate immunity; Liver sinusoidal endothelial cells; Natural killer T cells

Indexed keywords

ALPHA CD3 EPSILON MONOCLONAL ANTIBODY; CD3 ANTIBODY; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; CYTOKINE; FC RECEPTOR; GAMMA INTERFERON; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG; CD3 ANTIGEN; CD3E PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ANTIGEN BINDING; ANTIGEN PRESENTING CELL; ARTICLE; BINDING AFFINITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; ENDOTHELIUM CELL; IMMUNE RESPONSE; IMMUNOREGULATION; LIVER; LIVER CIRCULATION; LIVER METABOLISM; LIVER SINUSOID; LYMPH NODE; LYMPHOCYTE SUBPOPULATION; MACROPHAGE; MEMORY T LYMPHOCYTE; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RECEPTOR BINDING; SPLEEN; T LYMPHOCYTE ACTIVATION; THYMUS; TISSUE DISTRIBUTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CULTURE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; NATURAL KILLER CELL; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD11A; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; INTERFERON TYPE II; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, IGG; SPLEEN; T-LYMPHOCYTE SUBSETS; TISSUE DISTRIBUTION;

EID: 33644821892     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2005.02272.x     Document Type: Article

References (35)

1. Crispe IN Hepatic T cells and liver tolerance Nat Rev Immunol 2003 3 51 62
2. Limmer A Ohl J Kurts C et al. Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance Nat Med 2000 6 1348 54
3. Knolle PA Schmitt E Jin S Germann T Duchmann R Hegenbarth S Gerken G Lohse AW Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells Gastroenterology 1999 116 1428 40
4. Crispe IN Mehal WZ Strange brew: T cells in the liver Immunol Today 1996 17 522 5
5. Kronenberg M Gapin L The unconventional lifestyle of NKT cells Nat Rev Immunol 2002 2 557 68
6. Bendelac A Rivera MN Park SH Roark JH Mouse CD1-specific NK1 T cells: development, specificity, and function Annu Rev Immunol 1997 15 535 62
7. Eberl G MacDonald HR Rapid death and regeneration of NKT cells in anti-CD3epsilon- or IL-12-treated mice: a major role for bone marrow in NKT cell homeostasis Immunity 1998 9 345 53
8. Sprent J Surh CD T cell memory Annu Rev Immunol 2002 20 551 79
9. Masopust D Vezys V Marzo AL Lefrancois L Preferential localization of effector memory cells in nonlymphoid tissue Science 2001 291 2413 7
10. Reinhardt RL Khoruts A Merica R Zell T Jenkins MK Visualizing the generation of memory CD4 T cells in the whole body Nature 2001 410 101 5
11. Mehal WZ Azzaroli F Crispe IN Antigen presentation by liver cells controls intrahepatic T cell trapping, whereas bone marrow-derived cells preferentially promote intrahepatic T cell apoptosis J Immunol 2001 167 667 73
12. Huang L Soldevila G Leeker M Flavell R Crispe IN The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo Immunity 1994 1 741 9
13. Unsoeld H Krautwald S Voehringer D Kunzendorf U Pircher H Cutting edge. CCR7+ and CCR7- memory T cells do not differ in immediate effector cell function J Immunol 2002 169 638 41
14. Weerasinghe A Sekikawa H Watanabe H et al. Association of intermediate T cell receptor cells, mainly their NK1.1(-) subset, with protection from malaria Cell Immunol 2001 207 28 35
15. Hogquist KA Jameson SC Heath WR Howard JL Bevan MJ Carbone FR T cell receptor antagonist peptides induce positive selection Cell 1994 76 17 27
16. Takai T Li M Sylvestre D Clynes R Ravetch JV FcR gamma chain deletion results in pleiotrophic effector cell defects Cell 1994 76 519 29
17. Takai T Ono M Hikida M Ohmori H Ravetch JV Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice Nature 1996 379 346 49
18. Hazenbos WL Gessner JE Hofhuis FM et al. Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice Immunity 1996 5 181 8
19. Shinkai Y Rathbun G Lam KP et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V (D) J rearrangement Cell 1992 68 855 67
20. Burdin N Brossay L Koezuka Y et al. Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes J Immunol 1998 161 3271 81
21. Haanen JB Toebes M Cordaro TA Wolkers MC Kruisbeek AM Schumacher TN Systemic T cell expansion during localized viral infection Eur J Immunol 1999 29 1168 74
22. Valitutti S Muller S Cella M Padovan E Lanzavecchia A Serial triggering of many T-cell receptors by a few peptide-MHC complexes Nature 1995 375 148 51
23. Iezzi G Karjalainen K Lanzavecchia A The duration of antigenic stimulation determines the fate of naive and effector T cells Immunity 1998 8 89 95
24. Meuer SC Hodgdon JC Hussey RE Protentis JP Schlossman SF Reinherz EL Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones J Exp Med 1983 158 988 93
25. Cho BK Wang C Sugawa S Eisen HN Chen J Functional differences between memory and naive CD8 T cells Proc Natl Acad Sci USA 1999 96 2976 81
26. Nolte MA Belien JA Schadee-Eestermans I Jansen W Unger WW van Rooijen N Kraal G Mebius RE A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp J Exp Med 2003 198 505 12
27. Lovdal T Berg T Transcription of Fc (gamma) receptors in different rat liver cells Cell Biol Int 2001 25 821 24
28. Geissmann F Cameron TO Sidobre S Manlongat N Kronenberg M Briskin MJ Dustin ML Littman DR Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids PLoS Biol q47 2005 3 e113
29. Kambayashi T Assarsson E Lukacher AE Ljunggren HG Jensen PE Memory CD8+ T cells provide an early source of IFN-gamma J Immunol 2003 170 2399 408
30. Berenzon D Schwenk RJ Letellier L Guebre-Xabier M Williams J Krzych U Protracted protection to q48 Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells J Immunol 2003 171 2024 34
31. Dikopoulos N Wegenka U Kroger A Hauser H Schirmbeck R Reimann J Recently primed CD8+ T cells entering the liver induce hepatocytes to interact with naive CD8+ T cells in the mouse Hepatology 2004 39 1256 66
32. Grant AJ Lalor PF Hubscher SG Briskin M Adams DH MAdCAM-1 expressed in chronic inflammatory liver disease supports mucosal lymphocyte adhesion to hepatic endothelium (MAdCAM-1 in chronic inflammatory liver disease) Hepatology 2001 33 1065 72
33. Eksteen B Miles AE Grant AJ Adams DH Lymphocyte homing in the pathogenesis of extra-intestinal manifestations of inflammatory bowel disease Clin Med 2004 4 173 80
34. Guidotti LG Matzke B Schaller H Chisari FV High-level hepatitis B virus replication in transgenic mice J Virol 1995 69 6158 69
35. Guidotti LG Chisari FV Noncytolytic control of viral infections by the innate and adaptive immune response Annu Rev Immunol 2001 19 65 91