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Volumn 13, Issue 11, 2005, Pages 1915-1924

(+)-Z-Bisdehydrodoisynolic acid ameliorates obesity and the metabolic syndrome in female ZDF rats

Author keywords

Insulin resistance; Peroxisome proliferator activated receptor; Selective estrogen receptor modulators; Zucker diabetic fatty rat

Indexed keywords

ANIMALIA; RODENTIA;

EID: 33644818968     PISSN: 10717323     EISSN: None     Source Type: Journal    
DOI: 10.1038/oby.2005.236     Document Type: Article
Times cited : (7)

References (33)
  • 1
    • 0014185924 scopus 로고
    • Inhibition of 17-beta-oestradiol uptake in mouse uterus by doisynolic and allenoic acid derivatives: An in vitro differentiation between true oestrogens and pro-oestrogens
    • Terenius L. Inhibition of 17-beta-oestradiol uptake in mouse uterus by doisynolic and allenoic acid derivatives: an in vitro differentiation between true oestrogens and pro-oestrogens. Acta PharmacolToxicol. 1967;25:313-22.
    • (1967) Acta PharmacolToxicol , vol.25 , pp. 313-322
    • Terenius, L.1
  • 2
    • 0036756819 scopus 로고    scopus 로고
    • Activities of a non-classical estrogen, Z-bis-dehydrodoisynolic acid, with ERalpha and ERbeta
    • Meyers CY, Hou Y, Winters TA, Banz WJ, Adler S. Activities of a non-classical estrogen, Z-bis-dehydrodoisynolic acid, with ERalpha and ERbeta. J Steroid Biochem Mol Biol. 2002;82:33-44.
    • (2002) J Steroid Biochem Mol Biol , vol.82 , pp. 33-44
    • Meyers, C.Y.1    Hou, Y.2    Winters, T.A.3    Banz, W.J.4    Adler, S.5
  • 3
    • 0033816285 scopus 로고    scopus 로고
    • Absolute structure determination of the highly biologically active bisdehydrodoisynolic acids
    • Meyers CY, Hou Y, Robinson PD, Adler S, Banz WJ, Winters TA. Absolute structure determination of the highly biologically active bisdehydrodoisynolic acids. J Pharm Sci. 2000;89:513-8.
    • (2000) J Pharm Sci , vol.89 , pp. 513-518
    • Meyers, C.Y.1    Hou, Y.2    Robinson, P.D.3    Adler, S.4    Banz, W.J.5    Winters, T.A.6
  • 4
    • 0031451301 scopus 로고    scopus 로고
    • Transcriptional regulation of estrogen-responsive genes by non-steroidal estrogens: Doisynolic and allenolic acids
    • Meyers CY, Lutfl HG, Adler S. Transcriptional regulation of estrogen-responsive genes by non-steroidal estrogens: doisynolic and allenolic acids. J Steroid Biochem Mol Biol. 1997;62:477-89.
    • (1997) J Steroid Biochem Mol Biol , vol.62 , pp. 477-489
    • Meyers, C.Y.1    Lutfl, H.G.2    Adler, S.3
  • 5
    • 0023687363 scopus 로고
    • Doisynolic-type acids: Uterotropically potent estrogens which compete poorly with estradiol for cytosolic estradiol receptors
    • Meyers CY, Kolb VM, Gass GH, Rao BR, Roos CF, Dandliker WB. Doisynolic-type acids: uterotropically potent estrogens which compete poorly with estradiol for cytosolic estradiol receptors. J Steroid Biochem. 1988;31:393-404.
    • (1988) J Steroid Biochem , vol.31 , pp. 393-404
    • Meyers, C.Y.1    Kolb, V.M.2    Gass, G.H.3    Rao, B.R.4    Roos, C.F.5    Dandliker, W.B.6
  • 6
    • 85039356949 scopus 로고
    • Doisynolic acid type compounds as weight and appetite suppressing and control agents. Patent 5420161
    • Meyers CY. Doisynolic acid type compounds as weight and appetite suppressing and control agents. Patent 5420161. 1995.
    • (1995)
    • Meyers, C.Y.1
  • 7
    • 0037192464 scopus 로고    scopus 로고
    • Antioxidant effects of phyto-and synthetic-estrogens on cupric ion-induced oxidation of human low-density lipoproteins in vitro
    • Wilson T, March H, Banz WJ, et al. Antioxidant effects of phyto-and synthetic-estrogens on cupric ion-induced oxidation of human low-density lipoproteins in vitro. Life Sci. 2002;70:2287-97.
    • (2002) Life Sci , vol.70 , pp. 2287-2297
    • Wilson, T.1    March, H.2    Banz, W.J.3
  • 8
    • 0032407939 scopus 로고    scopus 로고
    • Comparative effects of the selective estrogen receptor modulators (-)-, ( + )- And (+/-)-Z bisdehydrodoisynolic acids on metabolic and reproductive parameters in male and female rats
    • Banz WJ, Winters TA, Hou Y, Adler S, Meyers CY. Comparative effects of the selective estrogen receptor modulators (-)-, ( + )- and (+/-)-Z bisdehydrodoisynolic acids on metabolic and reproductive parameters in male and female rats. Horm Metab Res. 1998;30:730-6.
    • (1998) Horm Metab Res , vol.30 , pp. 730-736
    • Banz, W.J.1    Winters, T.A.2    Hou, Y.3    Adler, S.4    Meyers, C.Y.5
  • 9
    • 0032530765 scopus 로고    scopus 로고
    • A genderrelated detect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor alpha- Deficient mice
    • Djouadi F, Weinheimer CJ, Saffitz JE, et al. A genderrelated detect in lipid metabolism and glucose homeostasis in peroxisome proliferator-activated receptor alpha- deficient mice. J Clin Invest. 1998;102:1083-91.
    • (1998) J Clin Invest , vol.102 , pp. 1083-1091
    • Djouadi, F.1    Weinheimer, C.J.2    Saffitz, J.E.3
  • 10
    • 0037657668 scopus 로고    scopus 로고
    • Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells
    • Mezel O, Banz WJ, Steger RW, Peluso MR, Winters TA, Shay N. Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells. J Nutr. 2003;133:1238-43.
    • (2003) J Nutr , vol.133 , pp. 1238-1243
    • Mezel, O.1    Banz, W.J.2    Steger, R.W.3    Peluso, M.R.4    Winters, T.A.5    Shay, N.6
  • 11
    • 0037014617 scopus 로고    scopus 로고
    • Raloxifene and risk of cardiovascular events
    • Mayer DF. Raloxifene and risk of cardiovascular events. JAMA. 2002;288:42-3.
    • (2002) JAMA , vol.288 , pp. 42-43
    • Mayer, D.F.1
  • 12
    • 0034966336 scopus 로고    scopus 로고
    • Effects of the selective estrogen receptor modulator, raloxifene, on the somatotropic axis and insulin-glucose homeostasis
    • Oleksik AM, Duong T, Pliester N, Asma G, Popp-Snijders C, Lips P. Effects of the selective estrogen receptor modulator, raloxifene, on the somatotropic axis and insulin-glucose homeostasis. J Clin Endocrinol Metab. 2001;86:2763-8.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2763-2768
    • Oleksik, A.M.1    Duong, T.2    Pliester, N.3    Asma, G.4    Popp-Snijders, C.5    Lips, P.6
  • 13
    • 0023032094 scopus 로고
    • Long-term effects of diethylstilbestrol (DES) on genetically obese and non-obese female Zucker rats
    • Finkelstein JA. Long-term effects of diethylstilbestrol (DES) on genetically obese and non-obese female Zucker rats. Brain Res Bull. 1986;17:885-8.
    • (1986) Brain Res Bull , vol.17 , pp. 885-888
    • Finkelstein, J.A.1
  • 14
    • 0018652549 scopus 로고
    • Genetic obestiy: Estrogenic influences on the body weight and food intake of lean and obese adult Zucker (fa/fa) rats
    • Gale SK, Van Itallie TB. Genetic obestiy: estrogenic influences on the body weight and food intake of lean and obese adult Zucker (fa/fa) rats. Physiol Behav. 1979;23:111-20.
    • (1979) Physiol Behav , vol.23 , pp. 111-120
    • Gale, S.K.1    Van Itallie, T.B.2
  • 15
    • 0021198508 scopus 로고
    • Effect of estrogen on lipoprotein lipase activity and cytoplasmic progestin binding sites in lean and obese Zucker rats
    • Gray JM, Greenwood MR. Effect of estrogen on lipoprotein lipase activity and cytoplasmic progestin binding sites in lean and obese Zucker rats. Proc Soc Exp Biol Med. 1984;175: 374-9.
    • (1984) Proc Soc Exp Biol Med , vol.175 , pp. 374-379
    • Gray, J.M.1    Greenwood, M.R.2
  • 17
    • 0020043045 scopus 로고
    • Influence of genetic hyperlipemia in the Zucker rat upon the lipemic response to graded estradiol exposure
    • Wilson JN, Wilson SP, Eaton RP. Influence of genetic hyperlipemia in the Zucker rat upon the lipemic response to graded estradiol exposure. Atherosclerosis. 1982;41:99-114.
    • (1982) Atherosclerosis , vol.41 , pp. 99-114
    • Wilson, J.N.1    Wilson, S.P.2    Eaton, R.P.3
  • 18
    • 0037203345 scopus 로고    scopus 로고
    • Lipoapoptosis: Its mechanism and its diseases
    • Unger RH, Orci L. Lipoapoptosis: its mechanism and its diseases. Biochim Biophys Acta. 2002;1585:202-12.
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 202-212
    • Unger, R.H.1    Orci, L.2
  • 19
    • 1942470630 scopus 로고    scopus 로고
    • Thiazolidinedione-induced congestive heart failure
    • Cheng AY, Fantus IG. Thiazolidinedione-induced congestive heart failure. Ann Pharmacother. 2004;38:817-20.
    • (2004) Ann Pharmacother , vol.38 , pp. 817-820
    • Cheng, A.Y.1    Fantus, I.G.2
  • 21
    • 33645077761 scopus 로고    scopus 로고
    • Effects of (+)-Z-bisdehydrodoisynolic acid on the rat prostate
    • abstr
    • Henry N, Hou Y, Roeder M, et al. Effects of (+)-Z-bisdehydrodoisynolic acid on the rat prostate. Biol Reprod. 2001;64:227 (abstr).
    • (2001) Biol Reprod , vol.64 , pp. 227
    • Henry, N.1    Hou, Y.2    Roeder, M.3
  • 22
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, Fahey GC, Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939-51.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey Jr., G.C.3
  • 23
    • 0020053033 scopus 로고
    • Doisynolic acids: Potent estrogens with very low affinity for estrogen receptors
    • Meyers CY, Kolb VM, Dandliker WB. Doisynolic acids: potent estrogens with very low affinity for estrogen receptors. Res Commun Chem Pathol Pharmacol. 1982;35:165-8.
    • (1982) Res Commun Chem Pathol Pharmacol , vol.35 , pp. 165-168
    • Meyers, C.Y.1    Kolb, V.M.2    Dandliker, W.B.3
  • 24
    • 0021475117 scopus 로고
    • Specific depletion of body fat in parabiotic partners of tube-fed obese rats
    • Harris RB, Martin RJ. Specific depletion of body fat in parabiotic partners of tube-fed obese rats. Am J Physiol. 1984;247:R380-6.
    • (1984) Am J Physiol , vol.247
    • Harris, R.B.1    Martin, R.J.2
  • 25
    • 0022626534 scopus 로고
    • Morphometry of canine coronary arteries, arterioles, and capillaries during hypertension and left ventricular hypertrophy
    • Tomanek RJ, Palmer PJ, Peiffer GL, Schreiber KL, Eastham CL, Marcus ML. Morphometry of canine coronary arteries, arterioles, and capillaries during hypertension and left ventricular hypertrophy. Circ Res. 1986;58:38-46.
    • (1986) Circ Res , vol.58 , pp. 38-46
    • Tomanek, R.J.1    Palmer, P.J.2    Peiffer, G.L.3    Schreiber, K.L.4    Eastham, C.L.5    Marcus, M.L.6
  • 26
    • 0024268251 scopus 로고
    • Microvascular morphometry and perfusion in renal hypertension-induced cardiac hypertrophy
    • Cimini CM, Weiss HR. Microvascular morphometry and perfusion in renal hypertension-induced cardiac hypertrophy. Am J Physiol. 1988;255:H 1384-90.
    • (1988) Am J Physiol , vol.255
    • Cimini, C.M.1    Weiss, H.R.2
  • 28
    • 0037200657 scopus 로고    scopus 로고
    • Signal cross-talk between estrogen receptor alpha and beta and the peroxisome proliferator-activated receptor gamma i in MDA-MB-231 and MCF-7 breast cancer cells
    • Wang X, Kilgore MW. Signal cross-talk between estrogen receptor alpha and beta and the peroxisome proliferator-activated receptor gamma I in MDA-MB-231 and MCF-7 breast cancer cells. Mol Cell Endocrinol. 2002;194:123-33.
    • (2002) Mol Cell Endocrinol , vol.194 , pp. 123-133
    • Wang, X.1    Kilgore, M.W.2
  • 29
    • 0029067225 scopus 로고
    • Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements
    • Keller H, Givel F, Perroud M, Wahli W. Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol Endocrinol. 1995;9:794-804.
    • (1995) Mol Endocrinol , vol.9 , pp. 794-804
    • Keller, H.1    Givel, F.2    Perroud, M.3    Wahli, W.4
  • 30
    • 0034847431 scopus 로고    scopus 로고
    • Prospects for prevention and treatment of cancer with selective PPARgamma modulators (SPARMs)
    • Sporn MB, Suh N, Mangelsdorf DJ. Prospects for prevention and treatment of cancer with selective PPARgamma modulators (SPARMs). Trends Mol Med. 2001;7:395-400.
    • (2001) Trends Mol Med , vol.7 , pp. 395-400
    • Sporn, M.B.1    Suh, N.2    Mangelsdorf, D.J.3
  • 31
    • 0036479110 scopus 로고    scopus 로고
    • Defects in heart, eye, and megakaryocytes in peroxisome proliferator activator receptor binding protein (PBP) null embryos implicate GATA family of transcription factors
    • Crawford SE, Qi C, Misra P, Stellmach V, Rao MS, Engel JD, Zhu Y, Reddy JK. Defects in heart, eye, and megakaryocytes in peroxisome proliferator activator receptor binding protein (PBP) null embryos implicate GATA family of transcription factors. J Biol Chem, 2002;277:3585-92.
    • (2002) J Biol Chem , vol.277 , pp. 3585-3592
    • Crawford, S.E.1    Qi, C.2    Misra, P.3    Stellmach, V.4    Rao, M.S.5    Engel, J.D.6    Zhu, Y.7    Reddy, J.K.8
  • 32
    • 2342597134 scopus 로고    scopus 로고
    • Bifunctional properties of peroxisome proliferatoractivated receptor gamma1 in KDR gene regulation mediated viii interaction with both Spl and Sp3
    • Sassa Y, Hata Y, Aiello LP, Taniguchi Y, Kohno K, Ishibashi T. Bifunctional properties of peroxisome proliferatoractivated receptor gamma1 in KDR gene regulation mediated viii interaction with both Spl and Sp3. Diabetes. 2004;53: 1222-9.
    • (2004) Diabetes , vol.53 , pp. 1222-1229
    • Sassa, Y.1    Hata, Y.2    Aiello, L.P.3    Taniguchi, Y.4    Kohno, K.5    Ishibashi, T.6
  • 33
    • 0034585795 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptor gamma increase the generation of vascular endothelial cell growth factor in vascular smooth muscle cells and in macrophages
    • Jozkowicz A, Dulak J, Piatkowska E, Placha W, Dembinska-Kiec A. Ligands of peroxisome proliferator-activated receptor gamma increase the generation of vascular endothelial cell growth factor in vascular smooth muscle cells and in macrophages. Acta Biochim Pol. 2000;47:1147-57.
    • (2000) Acta Biochim Pol , vol.47 , pp. 1147-1157
    • Jozkowicz, A.1    Dulak, J.2    Piatkowska, E.3    Placha, W.4    Dembinska-Kiec, A.5


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