Poly[3-(3,4-dihydroxyphenyl)glyceric acid], a new biologically active polymer from Symphytum asperum lepech. and S. caucasicum bieb. (boraginaceae)

Molecules

Volumn 10, Issue 9, 2005, Pages 1135-1144

  Barbakadze, Vakhtang ^a   Kemertelidze, Etheri ^a   Targamadze, Iraida ^a   Mulkijanyan, Karen ^a   Shashkov, Alexander S ^b   I Usov, Anatolii ^b  

^a INSTITUTE OF PHYSICS   (Georgia)

^b N D ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

Author keywords

3 (3,4 dihydroxyphenyl)glyceric acid; Caffeic acid; Poly oxy 1 carboxy 2 (3,4 dihydroxyphenyl)ethylene ; Symphytum asperum; Symphytum asperum caucasicum

Indexed keywords

BIOPOLYMER; CARBON; GLYCERIC ACID; POLY(3 (3,4 DIHYDROXYPHENYL)GLYCERIC ACID); POLY(3-(3,4-DIHYDROXYPHENYL)GLYCERIC ACID); PROTON;

BORAGINACEAE; CELL LINE; CHEMISTRY; CONFERENCE PAPER; HUMAN; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

BIOPOLYMERS; BORAGINACEAE; CARBON ISOTOPES; CELL LINE; GLYCERIC ACIDS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROTONS;

EID: 33644815806     PISSN: 14203049     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/10091135     Document Type: Conference Paper

References (26)

1. Barbakadze, V.V.; Kemertelidze, E.P.; Usov, A.I.; Kroes, B.H.; Quarles van Ufford, H.C.; Van den Worm, E.; Beukelman, C.J.; Van den Berg, A.J.J.; Labadie, R.P. Evaluation of Immunomodulatory Activity of Some Plant Polysaccharides. Proc. Georg. Acad. Sci., Biol. Ser. 1999, 25, 207-216.
2. Barbakadze, V.V.; Kemertelidze, E.P.; Dekanosidze, H.E.; Beruchashvili, T.G.; Usov, A.I. investigation of Glucofructans from Roots of Two Species of Comfrey Symphytum asperum Lepech. and S. caucasicum Bieb. Bioorg. Khim. 1992, 18, 671-679.
3. Barbakadze, V.V.; Kemertelidze, E.P.; Shashkov, A.S.; Usov, A.I.; Kroes, B.H.; C.J.; Van den Berg, A.J.J.; Labadie, R.P. Partial Characterization of a New Anticomplementary Dihydroxycinnamate-Derived Polymer from Symphytum asperum Lepech. Proc. Georg. Acad. Sci., Biol. Ser. 2000, 25, 207-216.
4. Barbakadze, V.V.; Kemertelidze, E.P.; Shashkov, A.S.; Usov, A.I. Structure of a New Anticomplementary Dihydroxycinnamate-Derived Polymer from Symphytum asperum (Boraginaceae). Mendeleev Commun. 2000, 10, 148-149.
5. Dyer, M.A. Applications of Absorption Spectroscopy of Organic Compounds; Prentice-Hall Inc.: Englewood Cliffs, NY, 1965.
6. Patt, S.L.; Schoolery J.N. Attached Proton Test for Carbon-13 NMR. J. Magn. Reson. 2000, 46, 535-539.
7. Higuchi, T. in Encyclopedia of Plant Physiology: Plant Carbohydrates II: Extracellular Carbohydrates; Tanner, W.; Loewus, F.A., Eds.; Springer-Verlag: Berlin, Heidelberg, New York, 1981; Vol. 13B, Chapter 9, pp. 194-224.
8. Lewis, N.G. a 20(th) Century Roller Coaster Ride: a Short Account of Lignification. Curr. Opin. Plant Biol. 1999, 2, 153-162.
9. Bernards, M.A.; Lewis, N.G. The Macromolecular Aromatic Domain in Suberized Tissue; a Changing Paradigm. Phytochemistry 1998, 47, 915-933.
10. Bernards, M.A.; Lopez, M.L.; Zajicek, J.; Lewis, N.G. Hydroxycinnamic Acid-Derived Polymers Constitute the Polyaromatic Domain of Suberin. J. Biol. Chem. 1995, 270, 7382-7386.
11. Lapierre, C.; Pollet, B.; Negrel, J. The Phenolic Domain of Potato Suberin: Structural Comparison With Lignin. Phytochemistry 1996, 42, 949-953.
12. Zeier, J.; Schreiber, L. Chemical Composition of Hypodermal and Endodermal Cell Walls and Xylem Vessels Isolated from Clivia mimata. Plant Physiol 1997, 113, 1223-1231.
13. Eberhardt, T.L.; Bernards, M.A.; He, L.; Davin, L.B.; Wooten, J.B.; Lewis, N.G. Lignification in Cell Suspension Cultures of Pinus Taeda. In situ Characterization of a Gymnosperm Lignin. J. Biol. Chem. 1993, 265, 21088-21096.
14. 13C Nuclear Magnetic Resonance Methods. Plant Physiol. 1994, 104, 527-533.
15. Kelley, C.J.; Harruff, R.C.; Carmack, M. The Polyphenolic Acids of Lithospermum Ruderale. II. Carbon-13 Nuclear Magnetic Resonance of Lithospermic and Rosmarinic Acids. J. Org. Chem. 1976, 41, 449-455.
16. Tezuka, Y.; Kasimu, R.; Li, J.X.; Basnet, P.; Tanaka, K.; Namba, T.; Kadota, S. Constituent of Roots of Salvia deserta Schang. (Xinjiang-Danshen). Chem. Pharm. Bull. 1998, 46, 107-112.
17. Ralf, J.; Helm, R.F.; Quideau, S.J. Lignin-Feruloyl Ester Cross-Links in Grasses. Part 2. Model Compound Syntheses. J. Chem. Soc. Perkin Trans. 1 1992, 2971-2980.
18. Barthomeuf, C.M.; Debiton E.; Barbakadze, V.V.; Kemertelidze, E.P. Evaluation of the Dietetic and Therapeutic Potential of a High Molecular Weight Hydroxycinnamate-Derived Polymer from Symphytum asperum Lepech. Regarding its Antioxidant, Antilipoperoxidant, Antiinflammatory, and Cytotoxic Properties. J. Agric. Food Chem. 2001, 49, 3942-3946.
19. Halkes, S.B.A.; Van den Berg, A.J.J.; Hoekstra, M.J.; Du Point, J.S.; Kreis, R.W. The Use of Tannic Acid in the Local Treatment of Burn Wounds: intriguing Old and New Perspectives. Wounds 2001, 13, 144-158.
20. Latha, B.; Babu, M. The involvement of Free Radicals in Burn injury: a review. Burns 2001, 27, 309-317.
21. Van den Worm, E.; Beukelman, C.J.; Van den Berg, A.J.J.; Kroes, B.H.; Labadie, R.P.; Van Dijk, H. Effects of Methoxylation of Apocynin and Analogs on the inhibition of Reactive Oxygen Species Production By Stimulated Human Neutrophils. Eur. J. Pharmacol. 2001, 433, 225-230.
22. Mattsson, E.; Van Dijk, H.; Van Kessel, K.; Verhoef, J.; Fleer, A.; Rollof, J. intracellular Pathways involved in Tumor Necrosis Factor-Alpha Release by Human Monocytes on Stimulation With Lipopolysaccharide Or Staphylococcal Peptidoglycan Are Partly Similar. J. Infect. Dis. 1996, 173, 212-218.
23. Kardava, L.; Gabunia, Kh.; Tevzadze, M.; Barbakadze, V.; Ghirdaladze, D.; Iosava, G.; Porakishvili, N. A Dihydroxycinnamate-Derived Polymer from Symphytum asperum increases Spontaneous in vitro Apoptosis of β-Chronic Lymphocytic Leukaemia Cells. Bull. Georg. Acad. Sci. 2000, 162, 47-50.
24. Kardava, L.; Kulikova, N.; Tevzadze, M.; Gabunia, Kh.; Barbakadze, V.; Ghirdaladze, D.; Iosava, G.; Porakishvili, N. The Cell Cycle Progression of β-Chronic Lymphocytic Leukaemia Cells in vitro. Proc. Georg. Acad. Sci. Biol. Ser. 2001, 27, 465-470.
25. Barbakadze, V. V.; Gakhokidze, R. A.; Shengelia, Z.S.; Usov, A. Preliminary investigation of Water-Soluble Polysaccharides from Georgian Plants. Khim. Prir. Soedin. 1989, 3, 330-335.
26. [Chem. Nat. Compd. (Eng. Transl). 1989, 25, 281-286].