PDZ-binding and di-hydrophobic motifs regulate distribution of Kir4.1 channels in renal cells

Journal of the American Society of Nephrology

Volumn 16, Issue 9, 2005, Pages 2608-2614

  Tanemoto, Masayuki ^a   Abe, Takaaki ^a,b   Ito, Sadayoshi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KIR4.1; PDZ PROTEIN; POTASSIUM CHANNEL; UNCLASSIFIED DRUG; VALINE; HYBRID PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM INWARDLY RECTIFYING CHANNEL, SUBFAMILY J, MEMBER 10; POTASSIUM INWARDLY-RECTIFYING CHANNEL, SUBFAMILY J, MEMBER 10;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; KIDNEY CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN TARGETING; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; BIOLOGICAL MODEL; CELL LINE; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; DOG; GENETICS; HYDROPHOBICITY; IN VITRO STUDY; KIDNEY DISTAL TUBULE; METABOLISM; MOLECULAR GENETICS; RAT; SITE DIRECTED MUTAGENESIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CELL MEMBRANE; DOGS; HUMANS; HYDROPHOBICITY; KIDNEY TUBULES, DISTAL; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS;

EID: 33644806107     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2005030266     Document Type: Article

References (29)

1. Jan LY, Jan YN: Cloned potassium channels from eukaryotes and prokaryotes. Annu Rev Neurosci 20: 91-123, 1997
2. Higashi K, Fujita A, Inanobe A, Tanemoto M, Doi K, Kubo T, Kurachi Y: An inwardly rectifying K(+) channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain. Am J Physiol Cell Physiol 281: C922-C931, 2001
3. Xu JZ, Hall AE, Peterson LN, Bienkowski MJ, Eessalu TE, Hebert SC: Localization of the ROMK protein on apical membranes of rat kidney nephron segments. Am J Physiol 273: F739-F748, 1997
4. Tanemoto M, Abe T, Onogawa T, Ito S: PDZ binding motif-dependent localization of K+ channel on the basolateral side in distal tubules. Am J Physiol Renal Physiol 287: F1148-F1153, 2004
5. Ito M, Inanobe A, Horio Y, Hibino H, Isomoto S, Ito H, Mori K, Tonosaki A, Tomoike H, Kurachi Y: Immunolocalization of an inwardly rectifying K+ channel, K(AB)-2 (Kir4.1), in the basolateral membrane of renal distal tubular epithelia. FEBS Lett 388: 11-15, 1996
6. Tanemoto M, Vanoye CG, Dong K, Welch R, Abe T, Hebert SC, Xu JZ: Rat homolog of sulfonylurea receptor 2B determines glibenclamide sensitivity of ROMK2 in Xenopus laevis oocyte. Am J Physiol Renal Physiol 278: F659-F666, 2000
7. Simon DB, Karet FE, Rodriguez-Soriano J, Hamdan JH, DiPietro A, Trachtman H, Sanjad SA, Lifton RP: Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K+ channel, ROMK. Nat Genet 14: 152-156, 1996
8. Tanemoto M, Kittaka N, Inanobe A, Kurachi Y: In vivo formation of a proton-sensitive K+ channel by heteromeric subunit assembly of Kir5.1 with Kir4.1. J Physiol 525: 587-592, 2000
9. Brown D, Breton S: Sorting proteins to their target membranes. Kidney Int 57: 816-824, 2000
10. Rothman JE: Mechanisms of intracellular protein transport. Nature 372: 55-63, 1994
11. Matter K: Epithelial polarity: Sorting out the sorters. Curr Biol 10: R39-R42, 2000
12. Pawson T, Scott JD: Signaling through scaffold, anchoring, and adaptor proteins. Science 278: 2075-2080, 1997
13. Tanemoto M, Fujita A, Higashi K, Kurachi Y: PSD-95 mediates formation of a functional homomeric Kir5.1 channel in the brain. Neuron 34: 387-397, 2002
14. Hunziker W, Harter C, Matter K, Mellman I: Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant. Cell 66: 907-920, 1991
15. Nishimura N, Balch WE: A di-acidic signal required for selective export from the endoplasmic reticulum. Science 277: 556-558, 1997
16. Songyang Z, Fanning AS, Fu C, Xu J, Marfatia SM, Chishti AH, Crompton A, Chan AC, Anderson JM, Cantley LC: Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science 275: 73-77, 1997
17. Daniels DL, Cohen AR, Anderson JM, Brunger AT: Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition. Nat Struct Biol 5: 317-325, 1998
18. Harrison SC: Peptide-surface association: The case of PDZ and PTB domains. Cell 86: 341-343, 1996
19. Stricker NL, Christopherson KS, Yi BA, Schatz PJ, Raab RW, Dawes G, Bassett DE Jr, Bredt DS, Li M: PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences. Nat Biotechnol 15: 336-342, 1997
20. Connors NC, Adams ME, Froehner SC, Kofuji P: The potassium channel Kir4.1 associates with the dystrophin-glycoprotein complex via alpha-syntrophin in glia. J Biol Chem 279: 28387-28392, 2004
21. Kachinsky AM, Froehner SC, Milgram SL: A PDZ-containing scaffold related to the dystrophin complex at the basolateral membrane of epithelial cells. J Cell Biol 145: 391-402, 1999
22. Loh NY, Newey SE, Davies KE, Blake DJ: Assembly of multiple dystrobrevin-containing complexes in the kidney. J Cell Sci 113: 2715-2724, 2000
23. Miranda KC, Khromykh T, Christy P, Le TL, Gottardi CJ, Yap AS, Stow JL, Teasdale RD: A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells. J Biol Chem 276: 22565-22572, 2001
24. Sheikh H, Isacke CM: A di-hydrophobic Leu-Val motif regulates the basolateral localization of CD44 in polarized Madin-Darby canine kidney epithelial cells. J Biol Chem 271: 12185-12190, 1996
25. Rapoport I, Chen YC, Cupers P, Shoelson SE, Kirchhausen T: Dileucine-based sorting signals bind to the beta chain of AP-I at a site distinct and regulated differently from the tyrosine-based motif-binding site. EMBO J 17: 2148-2155, 1998
26. Wang YJ, Wang J, Sun HQ, Martinez M, Sun YX, Macia E, Kirchhausen T, Albanesi JP, Roth MG, Yin HL: Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-I complexes to the Golgi. Cell 114: 299-310, 2003
27. Letourneur F, Klausner RD: A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains. Cell 69: 1143-1157, 1992
28. Giebisch G: Renal potassium channels: Function, regulation, and structure. Kidney Int 60: 436-445, 2001
29. Muto S, Asano Y, Wang W, Seldin D, Giebisch G: Activity of the basolateral K+ channels is coupled to the Na+-K+-ATPase in the cortical collecting duct. Am J Physiol Renal Physiol 285: F945-F954, 2003