Targeting superoxide dismutase to renal proximal tubule cells attenuates vancomycin-induced nephrotoxicity in rats

Free Radical Research

Volumn 37, Issue 4, 2003, Pages 373-379

  Nishino, Yoshihiro ^a   Takemura, Shigekazu ^a   Minamiyama, Yukiko ^a,b   Hirohashi, Kazuhiro ^a   Ogino, Tetsuya ^b   Inoue, Masayasu ^a   Okada, Shigeru ^b   Kinoshita, Hiroaki ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

Hexamethylenediamine conjugated superoxide dismutase; Oxidative stress; Renal dysfunction; Vancomycin

Indexed keywords

1,6 HEXANEDIAMINE; 8 HYDROXYDEOXYGUANOSINE; CREATININE; DNA; FREE RADICAL; SUPEROXIDE DISMUTASE; VANCOMYCIN;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BIOASSAY; CHEMOLUMINESCENCE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DNA DETERMINATION; DOSE RESPONSE; DRUG TARGETING; GLOMERULUS; HISTOPATHOLOGY; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; KIDNEY TUBULE NECROSIS; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; RAT; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ANTI-BACTERIAL AGENTS; BLOOD UREA NITROGEN; CHEMILUMINESCENT MEASUREMENTS; CREATININE; DEOXYGUANOSINE; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY GLOMERULUS; KIDNEY TUBULES, PROXIMAL; MALE; OXYGEN; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; SUPEROXIDES; TIME FACTORS; VANCOMYCIN;

ANIMALIA; GLOMERULUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; RATTUS NORVEGICUS; STAPHYLOCOCCUS AUREUS;

EID: 0037399831     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/1071576031000061002     Document Type: Article

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