Chemometric selection of a small set of pharmaceutical active substances used in determining the orthogonality and similarity of chromatographic systems

Analytica Chimica Acta

Volumn 562, Issue 1, 2006, Pages 73-84

  Van Gyseghem, E ^a   Elkihel, A ^a   Jimidar, M ^b   Sneyers, R ^b   Vander Heyden, Y ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Correlation coefficients color map; Kennard and Stone algorithm; Orthogonal chromatographic systems; Weighted holistic invariant molecular descriptors; Weighted average linkage dendrogram

Indexed keywords

CORRELATION THEORY; DRUG PRODUCTS;

CORRELATION COEFFICIENTS COLOR MAP; KENNARD AND STONE ALGORITHM; ORTHOGONAL CHROMATOGRAPHIC SYSTEMS; WEIGHTED HOLISTIC INVARIANT MOLECULAR DESCRIPTORS; WEIGHTED-AVERAGE-LINKAGE DENDROGRAM;

CHROMATOGRAPHIC ANALYSIS;

AMIODARONE; ASCORBIC ACID; CAFFEINE; CAMPHOR; CELIPROLOL; DESIPRAMINE; DIGITOXIN; ESTRADIOL; FAMOTIDINE; HISTAMINE; IBUPROFEN; LORAZEPAM; MICONAZOLE NITRATE; NADOLOL; NAPHAZOLINE; NICARDIPINE; NIZATIDINE; OXELADIN; OXPRENOLOL; PENTOXIFYLLINE; PHENOL; PINDOLOL; PIZOTIFEN; PRAZOSIN; PROCAINE; PROPIOMAZINE MALEATE; RESORCINOL; SULFAPYRIDINE; TIOTIXENE; UNINDEXED DRUG;

ALGORITHM; ARTICLE; CHROMATOGRAPHY; CORRELATION COEFFICIENT; DATA ANALYSIS; DRUG FORMULATION; DRUG SCREENING; PHYLOGENETIC TREE; PRIORITY JOURNAL;

DRYOBALANOPS;

EID: 33644781614     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2006.01.030     Document Type: Article

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