Spectroscopic measurements of photoinduced processes in human skin after topical application of the hexyl ester of 5-aminolevulinic acid

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 25, Issue 1-2, 2006, Pages 307-320

  Zhao, Lu ^a   Nielsen, Kristian P ^a   Juzeniene, Asta ^b   Juzenas, Petras ^b   Lani, Vladimir ^b   Ma, Li Wei ^b   Stamnes, Knut ^c   Stamnes, Jakob J ^a   Moan, Johan ^b  

^a UNIVERSITY OF BERGEN   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c STEVENS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

ALA Hex PDT; Erythema; Fluorescence excitation spectroscopy; Melanogenesis; Oxygen; Reflectance spectroscopy

Indexed keywords

AMINOLEVULINIC ACID HEXYL ESTER; PROTOPORPHYRIN;

ARTICLE; BLEACHING; DRUG EFFECT; ERYTHEMA; FLUORESCENCE SPECTROSCOPY; HUMAN; KINETICS; LIGHT EXPOSURE; MELANOGENESIS; NORMAL HUMAN; PRIORITY JOURNAL; REFLECTOMETRY; SKIN;

EID: 33644778934     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: 10.1615/JEnvironPatholToxicolOncol.v25.i1-2.200     Document Type: Article

References (40)

1. Casas A, Batlle A. Rational design of 5-aminolevulinic acid derivatives aimed at improving photodynamic therapy. Curr Med Chem Anti-Canc Agents. 1998; 2:465-475.
2. Lopez RF, Lange N, Guy R, Bentley MV. Photodynamic therapy of skin cancer: controlled drug delivery of 5-ALA and its esters. Adv Drug Deliv Rev. 2004; 56(1):77-94.
3. Moan J, Qian P. Review: An outline of the hundred-year history of PDT. Anticancer Res. 2003; 23(5A):3591-3600.
4. Juzeniene A, Juzenas P, Iani V, Moan J. Topical application of 5-aminolevulinic acid and its methylester, hexylester and octylester derivatives: considerations for dosimetry in mouse skin model. Photochem Photobiol. 2002; 76(3):329-334.
5. Stender IM, Bech-Thomsen N, Poulsen T, Wulf HC. Photodynamic therapy with topical delta-aminolevulinic acid delays UV photocarcinogenesis in hairless mice. Photochem Photobiol. 1997; 66:493-496.
6. Sharfaei S, Juzenas P, Moan J, Bissonnette R. Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice. Arch Dermatol Res. 2002; 294:237-242.
7. Monfrecola G, Procaccini EM, D'Onofrio D, Roberti G, Liuzzi R, Staibano S, Manco A, De Rosa G, Santoianni P. Hyperpigmentation induced by topical 5-aminolaevulinic acid plus visible light. J Photochem Photobiol B:Biol. 2002; 68:147-155.
8. Touma DJ, Gilchrest BA. Topical photodynamic therapy: a new tool in cosmetic dermatology. Semin Cutan Med Surg 2003; 22(2):124-130.
9. Dougherty TJ, Gomer CJ, Henderson BW, Jori G, Kessel D, Korbelik M, Moan J, Qian P. Photodynamic Therapy. J Natl Cancer Inst 1998; 90(12):889-905.
10. Moan J. On the diffusion length of singlet oxygen in cells and tissues. J Photochem Photobiol 1990; 6:343-347.
11. Kochevar E. Singlet oxygen signaling: from intimate to global. Science's STKE, February 24, 2004; 221:pe7-7.
12. Moan J, Sommer S. Oxygen dependence of the photosensitizing effect of hematoporphyrin derivative in NHIK 3025 cells. Cancer Res. 1985; 45:1608-1610.
13. van der Veen N, Hebeda KM, de Bruijn HS, Star WM. Photodynamic effectiveness and vasoconstriction in hairless mouse skin after topical 5-aminolevulinic acid and single- or two-fold illumination. Photochem Photobiol. 1999; 70(6):921-929.
14. Star WM, Marijnissen HP, Van Berg-Blok AE, Versteeg JA, Franken KA, Reinhold HS. Destruction of rat mammary tumor and normal tissue microcirculation by hematoporphyrin derivative photoradiation observed in vivo in sandwich observation chambers. Cancers Res. 1986; 46(5):2532-2540.
15. Uehlinger P, Zellweger M, Wagnieres G, Juillerat-Jeanneret L, van den Bergh H, Lange N. 5-Aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells. J Photochem Photobiol B:Biol. 2000; 54(1):72-80.
16. Pottier RH, Chow YF, LaPlante JP, Truscott TG, Kennedy JC, Beiner LA. Non-invasive technique for obtaining fluorescence excitation and emission spectra in vivo. Photochem Photobiol 1986; 44:679-687.
17. Juzenas P, Iani V, Bagdonas S, Rotomskis R, Moan J. Fluorescence spectroscopy of normal mouse skin exposed to 5-aminolaevulinic acid and red light. J Photochem Photobiol, B: Biol. 2001; 61:78-86.
18. Bonnett R, Martinez G. Photobleaching of sensitisers used in photodynamic therapy. Tetrahedron. 2001; 57:9513-9547.
19. Eichler J, Knof J, Lenz H. Measurements on the depth of penetration of light (0.35-1.0 μm) in tissue. Rad And Environm Biophys 1977; 14:239-242.
20. Moan J, Qian P, Sorensen R, Iani V, Nesland JM. The biophysical foundations of photodynamic therapy. Endoscopy 1998; 30:387-391.
21. Juzenas P, Juzeniene A, Kaalhus O, Iani V, Moan J. Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo. Photochem Photobiol Sci. 2002; 1:745-748.
22. Nielsen KP, Zhao L, Juzenas P, Stamnes JJ, Stamnes K, Moan J. Reflectance spectra of pigmented and non-pigmented skin in the UV spectral region. Photochem Photobiol 2004; 80(3):450-455.
23. Tromberg BJ, Orenstein A, Kimel S, Barker SJ, Hyatt J, Nelson JS, Berns MW. In vivo tumor oxygen tension measurements for the evaluation of the efficiency of photodynamic therapy. Phtochem Photobiol. 1990; 52:375-385.
24. Foster TH, Murant RS, Bryant RG, Knox RS, Gibson SL, Hilf R. Oxygen consumption and diffusion effects in photodynamic therapy. Radiat Res. 1991; 126:296-303.
25. Sitnik TM, Hampton JA, Henderson BW. Reduction of tumor oxygenation during and after photodynamic therapy in vivo: effects of fluence rate. Br J Caner. 1998; 77:1386-1394.
26. Zilberstein J, Bromberg A, Frantz A, Rosenbach-Belkin V, Kritzmann A, Pfefermann R, Salomon Y, Scherz A. Light-dependet oxygen consumption in bacteriochlorophyII-serine-treated malenoma tumors: on-line determination using a tissue-inserted oxygen microsensor. Photochem Photobiol 1997; 65:1012-1019.
27. 2 dynamics during photodynamic therapy with verteporfin. Photochem Photobiol. 2001; 74:700-706.
28. Blant SA, Woodtli A, Fontolliet C, Van den Bergh H, Monnier P. In vivo fluence rate effect in photodynamic therapy of early cancers with tetra (m-hydroxyphenyl) chlorine. Photochem Photobiol. 1996; 64:963-968.
29. Van Geel IPJ, Oppelaar H, Rijken PFJW, Bernsen HJJA, Hagemeier NEM, van dr Kogel AJ, Hodgkiss RJ, Stewart FA. Vascular perfusion and hypoxic areas in RIF-1 tumours after photodynamic therapy. Br J Cancer. 1996; 73:288-293.
30. 2 changes during photodynamic therapy depend upon photosensitizer type and time after injection. Comparative Biochemistry and Physiology Part A. 2002; 132:177-84.
31. Henderson BW, Busch TM, Vaughan LA, Frawley NP, Babich D, Sosa TA, Zolo JD, Dee AS, Cooper MT, Bellnier DA, Greco WR, Oseroff AR. Photofrin photodynamic therapy can significantly deplete or preserve oxygenation in human basal cell carcinomas during treatment, depending on fluence rate. Cancer Res. 2000; 60:525-529.
32. Porges SB, Kaidbey KH, Grove GL. Quantification of visible light-induced melanogenesis in human skin. Photodermatol 1988; 5(5):197-200.
33. Rosen CF, Jacques SL, Stuart ME, Gange RW. Immediate pigment darkening: visual and reflectance spectrophotometric analysis of action spectrum. Photochem Photobiol 1990; 51(5):583-585.
34. Wiegell SR, Stender IM, Na R, Wulf HC. Pain associated with photodynamic therapy using 5-aminolevulinic acid or 5-aminolevulinic acid methylester on tape-stripped normal skin. Arch Dermatol. 2003; 139:1173-1177.
35. Fehr MK, Hornung R, Degen A, Schwarz VA, Fink D, Haller U, Wyss P. Photodynamic therapy of vulvar and vaginal condyloma and intraepithelial neolasia using topically applied 5-aminolevulinic acid. Lasers Surg Med. 2002; 30:273-279.
36. Itoh Y, Ninomiya Y, Tjima S, Ishibashi A. Photodynamic therapy of acne vulgaris with topical delta-aminolaevulinic acid and incoherent light in Japanese patients. Br J Dermatol. 2001; 144:575-579.
37. Bissonnette R, Shapiro J, Zeng H, Mclean DI, Lui H. Topical photodynamic therapy with 5-aminolaevulinic acid does not induce hair regrowth in patients with extensive alopecia areata. Br J Dermatol. 2000; 143:1032-1035.
38. Hillemanns, P, Untch M, Dannecher C, Baumgartner R, Stepp H, Diebold J, Weingandt H, Prove F, Korell M. Photodynamic therapy of vulvar intraepithelial neoplasia using 5-aminolevulinic acidl. Int J Cancer. 2000; 85:649-653.
39. Nayeemuddin FA, Wong M, Yell J, Rhodes LE. Topical photodynamic therapy in disseminated superficial actinic porokeratosis. Clin Exp Dermatol. 2002; 27:703-706.
40. Karrer S, Abels C, Landthaler M, Szeimies RM. Topical photodynamic therapy for localized scleroderma. Acta Derm Venereol. 2000; 80:26-27.