Tumor PO2 changes during photodynamic therapy depend upon photosensitizer type and time after injection

Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology

Volumn 132, Issue 1, 2002, Pages 177-184

  Pogue, Brian W ^a   O'Hara, Julia A ^b   Goodwin, Isak A ^a   Wilmot, Carmen J ^b   Fournier, Gregory P ^a   Akay, Altug R ^a   Swartz, Harold ^b  

^a DARTMOUTH COLLEGE   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Benzoporphyrin derivative; EPR; Oxygen; Photochemotherapy; Photodynamic; PO2; RIF 1 tumor; Singlet oxygen

Indexed keywords

AMINOLEVULINIC ACID; BENZOPORPHYRIN DERIVATIVE; PHOTOSENSITIZING AGENT; PROTOPORPHYRIN; OXYGEN; PORPHYRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CANCER TISSUE; CELL DAMAGE; CONFERENCE PAPER; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; MOUSE; NONHUMAN; OXIMETRY; OXYGEN TENSION; OXYGEN TISSUE LEVEL; PHOTODYNAMIC THERAPY; RADIATION DOSE; SKIN TUMOR; TISSUE OXYGENATION; ANIMAL; ARTICLE; CANCER TRANSPLANTATION; CELL CULTURE; CLASSIFICATION; LIGHT; METABOLISM; METHODOLOGY; NEOPLASM; PHOTOCHEMOTHERAPY; PRESSURE; TIME;

ANIMALIA;

ANIMALS; ELECTRON SPIN RESONANCE SPECTROSCOPY; LIGHT; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS; OXYGEN; PARTIAL PRESSURE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; PROTOPORPHYRINS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0036010228     PISSN: 10956433     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1095-6433(01)00545-1     Document Type: Conference Paper

References (24)

1. Depletion of tumor oxygenation during photodynamic therapy: Detection by the hypoxia marker EF3
2. Benzophenothiazine and benzoporphyrin derivative combination phototherapy effectively eradicates large murine sarcomas
3. Analysis of acute vascular damage after photodynamic therapy using benzoporphyrin derivative (BPD)
4. Age-related macular degeneration: Update for Primary Care
5. Oxygen consumption and diffusion effects in photodynamic therapy
6. Effects of photodynamic therapy on xenografts of human mesothelioma and rat mammary-carcinoma in Nude-Mice
7. Photofrin photodynamic therapy can significantly deplete or preserve oxygenation in human basal cell carcinomas during treatment, depending on fluence rate
8. Hemodynamic effects of 5-aminolevulinic acid in humans
9. In vivo fluence rate and fractionation effects on tumor response and photobleaching: Photodynamic therapy with two photosensitizers in an orthotopic rat tumor model
10. The role of photodynamic therapy in dermatology
11. Lithium phthalocyanine: A probe for EPR oximetry in viable biological systems
12. Photodynamic therapy and cancer of the esophagus
13. Combination of 5-aminol evulinic acid and a hematoporphyrin derivative in the photodynamic therapy of human colon-carcinoma cells
14. Photodynamic therapy of orthotopic prostate cancer with benzoporphyrin derivative: Local control and distant metastases
15. Oxygenation in a murine tumor following radiation: An in vivo electron paramagnetic resonance oximetry study
16. 2 dynamics during photodynamic therapy with verteporfin
17. Photodynamic treatment of the RIF-1 tumor with verteporfin with online monitoring of tissue oxygen using electron paramagnetic resonance oximetry
18. Liposomal delivery of a photosensitizer, benzoporphyrin derivative monoacid ring A (BPD), to tumor tissue in a mouse tumor model
19. Photodynamic therapy with verteporfin for choroidal neovascularization caused by age-related macular degeneration: Results of retreatments in a phase 1 and 2 study
20. Photodynamic therapy reduces tumor oxygenation during and after treatment: Effects of fluence rate
21. In vivo tumor oxygen tension measurements for the evaluation of the efficiency of photodynamic therapy
22. The importance of fluence rate in photodynamic therapy: Is there a parallel with ionizing-radiation dose-rate effects
23. Superficial blood flow following photodynamic therapy of malignant non-melanoma skin tumours measured by laser Doppler perfusion imaging
24. Side effects and photosensitization of human tissues after aminolevulinic acid