PC technology™ as a platform for drug delivery: From combination to conjugation

Expert Opinion on Drug Delivery

Volumn 3, Issue 2, 2006, Pages 289-298

  Lewis, Andrew L ^a  

^a BIOCOMPATIBLES UK LTD   (United Kingdom)

Author keywords

Biocompatibility; Combination product; Gene therapy; Hydrogels; Medical device; Micelles; PCylation; Phosphorylcholine; Stimulus responsive materials; Targeted drug delivery

Indexed keywords

2 METHACRYLOYLOXYETHYLPHOSPHORYLCHOLINE; ABT 578; ACETYLSALICYLIC ACID; COPOLYMER; DEXAMETHASONE; DRUG VEHICLE; OLIGONUCLEOTIDE; PARACETAMOL; PEGINTERFERON; PHOSPHORYLCHOLINE; PLASMID DNA; POLYMER; BIOMATERIAL; DNA;

ARTICLE; BIOCOMPATIBILITY; DEVICE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; HYDROGEL; HYDROPHOBICITY; NONHUMAN; PHYSICAL CHEMISTRY; POLYMERIZATION; SOFT CONTACT LENS; GENETICS; METABOLISM; MICELLE; VEHICLES;

COATED MATERIALS, BIOCOMPATIBLE; DNA; MICELLES; PHOSPHORYLCHOLINE; POLYMERS; VEHICLES;

EID: 33644777418     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.3.2.289     Document Type: Article

References (48)

1. SWANSON N, STEPHENS-LLOYD A, GERSHLICH A: Drug eluting stents: from lab bench to bedside. Cardiol. News (2001) 4:12-15.
2. GRUBE E: Drug eluting stents: an overview. Cath. Lab. Digest (2001) 9:52-55.
3. LEWIS AL: Phosphorylcholine-based polymers and their use in the reduction of biofouling. Colloids Surf. B. Biointerfaces (2000) 21:261-275.
4. PATTI G, PASCERI V, CARMINATI P et al.: Effect of dexamethasone-eluting stents on systemic inflammatory response in patients with unstable angina pectoris or recent myocardial infarction undergoing percutaneous coronary intervention. Am. J. Cardiol. (2005) 95:502-505.
5. BUELLESFELD L, GRUBE E: ABT-578-eluting stents. The promising successor of sirolimus- and paclitaxel-eluting stent concepts? Herz (2004) 29:167-170.
6. ZWALL RF, COMFURIUS P, VAN DEENEN LL: Membrane asymmetry and blood coagulation. Nature (1977) 268:358-360.
7. PARKER AP, REYNOLDS PA, LEWIS AL et al.: Investigation into potential mechanisms promoting biocompatibility of polymeric biomaterials containing the phosphorylcholine moiety: a physicochemical and biological study Colloids Surf. B: Biointerfaces (2005) 46(4):204-217.
8. ISHIHARAK, NOMURA H, MIHARA T et al.: Why do phospholipid polymers reduce protein adsorption? J. Biomed. Mater. Res. (1998) 39:323-330.
9. HAYWARD JA, CHAPMAN D: Biomembrane surfaces as models for polymer design: the potential for haemocompatility. Biomaterials (1984) 5:135-142.
10. DURRANI AA, HAYWARD JA, CHAPMAN D: Biomembranes as models for polymer surfaces II. The syntheses of reactive species for covalent coupling of phosphorylcholine to polymer surfaces. Biomaterials (1986) 7:121-125.
11. LEWIS AL, DRIVER MJ: Preventing foul play. Chem. Br. (1999) 35:42-45.
12. NAKABAYASHI N, WILLIAMS DF: Preparation of non-thrombogenic materials using 2-methacryloyloxyethyl phosphorylcholine. Biomaterials (2003) 24:2431-2435.
13. WATANABE J, ISHIHARA K: Biointerface, bioconjugation, and biomatrix based on bioinspired phospholipid polymers (Chapter 3) In: Handbook of Nanostructured Biomaterials and their Application in Nanobiotechnology. HS Nalwa (Ed.), American Scientific Publishers, California, CA, USA (2005) 1:129-165.
14. LEWIS AL: Phosphorylcholine (PC) technology. In: Encyclopaedia of Biomaterials and Biomedical Engineering. GE Wnek, GL Bowlin (Eds), Marcel Dekker, Inc., New York, NY, USA (2004):1198-1211.
15. YOUNG G, BOWERS RW, HALL B et al.: Clinical comparison of omafilcon A with four control materials. CLAO J. (1997) 23:249-258.
16. LEWIS AL, STRATFORD PW: Phosphorylcholine-coated stents. J. Long Term Eff. Med Implants (2002) 12:231-250.
17. BERRY JA, BIEDLINGMAIER JF, WHELAN PJ: In vitro resistance to bacterial biofilm formation on coated fluoroplastic tympanostomy tubes. Otolaryngol. Head Neck Surg. (2000) 123:246-251.
18. LLOYD AW, DROPCOVA S, FARAGHER RG et al.: The development of in vitro biocompatibility tests for the evaluation of intraocular lenses. J. Mater. Sci. Mater. Med. (1999) 10:621-627.
19. RUSSELL JC: Bacteria, biofilms and devices: the possible protective role of phosphorylcholine materials. J. Endourol. (2000) 1:39-42.
20. DE SOMER F, VAN BELLEGHEM Y, CAES F et al.: Phosphorylcholine coating offers natural platelet preservation during cardiopulmonary bypass. Perfusion (2002) 1:39-44.
21. LEWIS AL, HUGHES PD, KIRKWOOD LC et al.: Synthesis and characterisation of phosphorylcholine-based polymers useful for coating blood filtration devices. Biomaterials (2000) 21:1847-1859.
22. MATYJASZEWSKI K: From atom transfer radical addition to atom transfer radical polymerization. Current Organic Chem. (2002) 6:67-82.
23. ROBINSON KL, KHAN MA, DE PAZ BANEZ MV et al.: Controlled polymerisation of 2-hydroxyethyl methacrylate by ATRP at ambient temperature. Polym. Mater. Sci. Eng. (2001) 84:58-59.
24. MA Y, ARMES SP, BILLINGHAM NC: Controlled structure water-soluble polymers: aqueous aton transfer radical polymerisation of a carboxybetaine monomer. Polym. Mater. Sci. Eng. (2001) 84:143-144.
25. LEWIS AL, CUMMING ZC, GOREISH HH et al.: Crosslinkable coatings from phosphorylcholine-based polymers. Biomaterials (2001) 22:99-111.
26. ROTHMAN ML, LEWIS AL: Biocompatibles drug eluting stents (Chapter 36). In: Handbook of Stems. PW Serruys, BJ Rensing (Eds), Martin Dunitz Ltd, London, UK (2001):299-310.
27. DE SCHEERDER IK, LEWIS AL, COLLIAS AC: Phosphorylcholine (PC Technology™) coated stents as a drug delivery platform (Chapter 16). In: Local Drug Delivery For Coronary Artery Disease. E Camenzind, IK De Scheerder (Eds), Taylor and Francis, London, UK (2005):139-150.
28. TANG Y, LU JR, LEWIS AL et al.: Swelling of zwitterionic polymer films characterised by spectroscopic ellipsometry, Macromolecules (2001) 34:8768-8776.
29. CLARKE S, DAVIES MC, ROBERTS CJ et al.: Surface mobility of 2-methacryloyloxyethyl phosphorylcholine-co-lauryl methacrylate polymers. Langmuir (2000) 16:5116-5122.
30. LEWIS AL, VICK TA, COLLIAS AM et al.: Phosphorylcholine-based polymers for stent drug delivery. J. Mater. Sci. Mater. Med. (2001) 12:865-870.
31. TANG Y, SU TJ, ARMSTRONG J et al.: Structure of phosphorylcholine incorporated biocompatible polymer films. Macromolecules (2003) 36:8440-8448.
32. KONNO T, WATANABE J, ISHIRARA K: Enhanced solubility of paclitaxel using water-soluble and biocompatible 2-methacryloyloxyethyl phosphorylcholine polymers. J. Biomed. Mater. Res. (2003) 65:209-214.
33. LOBB EJ, MA I, BILLINGHAM NC et al.: Facile synthesis of well-defined, biocompatible phosphorylcholine-based methacrylate copolymers via atom transfer radical polymerisation at 20°C. J. Am. Chem. Soc. (2001) 123:7913-7914.
34. MA I, LOBB EJ, BILLINGHAM NC et al.: Synthesis of biocompatible polymers 1. Homopolymerisation of 2-methacryloyloxyethyl phosphorylcholine via ATRP in protic solvents: an optimisation study. Macromolecules (2002) 35:9306-9314.
35. MA I, TANG Y, BILLINGHAM NC, ARMES SP: Well-defined biocompatibles block copolymers via atom transfer radical polymerization of 2-methacryloyloxyethyl phosphorylcholine in protic media. Macromolecules (2003) 36:3475-3484.
36. SALVAGE JP, ROSE SF, PHILLIPS GJ et al.: Novel biocompatibles phosphorylcholine-based self-assembled nanoparticles for drug delivery. J. Control. Release (2005) 104:259-270.
37. LICCARDI M, TANG Y, BILLINGHAM NC et al.: Synthesis of novel folic acid-functionalized biocompatible block copolymers by atom transfer radical polymerization for gene delivery and encapsulation of hydrophobic drugs. Biomacromolecules (2005) 6:1085-1096.
38. DU J, TANG Y, LEWIS AL, ARMES SP: pH-Sensitive vesicles based on a biocompatible zwitterionic diblock copolymer. J. Am. Chem. Soc. (2005) 127(51):17982-17983.
39. TANG Y, ARMES SP, MORRIS CJ et al.: Synthesis and characterization of biocompatible thermo-responsive gelators based on ABA triblock copolymers. Biomacromolecules (2005) 6:994-999.
40. LI Y, NARAIN R, MA Y et al.: Biomimetic thermoresponsive star diblock gelators. Chem. Comm. (2004) 7(23):2746-2747.
41. PALMER RR, LEWIS AL, KIRKWOOD LC et al.: Biological evaluation and drug delivery application of cationically-modified phospholipid polymers. Biomaterials (2004) 25(19):4785-4796.
42. LEWIS AL, VICK TA: Site-specific drug delivery from coronary stents. Drug Del. Systems Sci. (2001) 1:65-71.
43. WALTER DH, CEJNA M, DIAZ-SANDOVAL L et al.: Local gene transfer of phVEGF-2 plasmid by gene-eluting stents: an alternative strategy for inhibition of restenosis. Circulation (2004) 110:36-45.
44. LAM JK, STOLNIK ST, ARMES SP et al.: Phosphorylcholine-based diblock copolymers: new synthetic vectors for gene delivery. J. Control Release (2004) 100:293-312.
45. CHIM YT, LAM JK, MA Y et al.: Structural study of DNA condensation induced by novel phosphorylcholine-based copolymers for gene delivery and relevance to DNA protection. Langmuir (2005) 21:3591-3598.
46. LAM JK, LEWIS AL, ARMES SP et al.: Folate conjugated phosphorylcholine-polycation copolymers for gene delivery. Transactions of the CRS 32nd Annual Meeting & Exposition. Miami, FL, USA (2005):Abstract 0595.
47. ZHAO XB, ZHANG Z, PAN F et al.: Solution pH regulated adsorption of diblock phosphorylcholine copolymers. Langmuir (2005) 21:9597-9603.
48. MIYAMOTO D, WATANABE J, ISHIHARA K: Effect of water-soluble phospholipid polymers conjugated with papain on the enzymatic stability. Biomaterials (2004) 25:71-76.