The risk of hepatocellular carcinoma in cirrhotic patients with small liver nodules on MRI

American Journal of Gastroenterology

Volumn 101, Issue 3, 2006, Pages 533-540

  Shah, Tilak U ^a   Semelka, Richard C ^a   Pamuklar, Ertan ^a   Firat, Zeynep ^a   Gerber, Richard D ^a   Shrestha, Roshan ^a   Russo, Mark W ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CANCER INCIDENCE; CANCER RISK; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HEALTH STATUS; HUMAN; KAPLAN MEIER METHOD; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER NODULE; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; TREATMENT INDICATION;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PRECANCEROUS CONDITIONS; PROSPECTIVE STUDIES; RISK;

EID: 33644776876     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2006.00450.x     Document Type: Article

References (27)

1. Bosch XF Ribes J Mireia D et al. Primary liver cancer: Worldwide incidence and trends Gastroenterology 2004 127 S5 16
2. El Serag HB Mason AC Rising incidence of hepatocellular carcinoma in the United States N Engl J Med 1999 10 745 50
3. Llovet JM Bustamante J Castells A et al. Natural history of untreated nonsurgical hepatocellular carcinoma: Rationale for the design and evaluation of therapeutic trials Hepatology 1999 29 62 7
4. Figueras J Jaurietta E Vallas C et al. Resection or transplantation for hepatocellular carcinoma in cirrhotic patients: Outcomes based on indicated treatment strategy J Am Coll Surg 2000 19 580 7
5. Bismuth H Chiche L Adam R et al. Liver resection versus transplantation for hepatocellular carcinoma in cirrhotic patients Ann Surg 1993 218 145 51
6. Mazzaferro V Regalia E Doci R et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis N Engl J Med 1996 334 693 9
7. Theise ND Park YN Kojiro M Dysplastic nodules and hepatocarcinogenesis Clin Liver Dis 2002 6 497 512
8. Winter TC III. Takayasu K Muramatsu Y et al. Early advanced hepatocellular carcinoma: Evaluation of CT and MRI appearance with MRI correlation Radiology 1994 192 379 87
9. Yamashita Y Mitsuzaki K Yi T et al. Small hepatocellular carcinoma in patients with chronic liver damage: Prospective comparison of detection with dynamic MR imaging and helical CT of the whole liver Radiology 1996 200 79 84
10. Rode A Bancel B Douek P et al. Small nodule detection in cirrhotic livers: Evaluation with ultrasound, spiral CT, and MRI and correlation with pathologic examination of the explanted liver J Comput Assist Tomogr 2001 25 327 36
11. Ferrell L Wright T Lake J et al. Incidence and diagnostic features of macroregenerative nodules vs. small hepatocellular carcinoma in cirrhotic livers Hepatology 1992 16 1372 81
12. Borzio M Fargion S Borzio F et al. Impact of large regenerative, low grade and high-grade dysplastic nodules in hepatocellular carcinoma development J Hepatol 2003 39 208 14
13. Choi BI Takayasu K Han MC Small hepatocellular carcinomas and associated nodular lesions of the liver: Pathology, pathogenesis, and imaging findings AJR Am J Roentgenol 1993 160 1177 87
14. Matsui O Kadoya M Kameyama T et al. Adenomatous hyperplastic nodules in the cirrhotic liver: Differentiation from hepatcellular carcinoma with MR imaging Radiology 1989 173 123 6
15. Matsui O Kadoya M Kameyama T et al. Benign and malignant nodules in cirrhotic livers: Distinction based on blood supply Radiology 1991 178 493 7
16. Earls JP Theise ND Weinreb JC et al. Dysplastic nodules and hepatocellular carcinoma: Thin-section MR imaging of explanted cirrhotic livers with pathologic correlation Radiology 1996 201 207 14
17. Mastropasqua M Braga L Kanematsu M et al. Hepatic nodules in liver transplantation candidates: MR imaging and underlying hepatic disease Magn Reson Imaging 2005 23 557 62
18. International Working Party Terminology of nodular hepatocellular lesions Hepatology 1995 22 983 93
19. Kaplan EL Meier P Non-parametric estimation for incomplete observation J Am Stat Assoc 1958 53 457 81
20. Cox DR Regression models and life tables J R Stat Soc 1972 34 87 220
21. Krinsky GA Lee VS Theise ND et al. Hepatocellular carcinoma and dysplastic nodules in patients with cirrhosis: Prospective diagnosis with MR imaging and explant correlation Radiology 2001 219 445 54
22. Borzio M Bruno S Massimo R et al. Liver cell dysplasia is a major risk factor for hepatocellular carcinoma in cirrhosis: A prospective study Gastroenterology 1995 108 812 7
23. Seki S Sakaguchi H Kitada T et al. Outcomes of dysplastic nodules in human cirrhotic liver: A clinico-pathologic study Clin Cancer Res 2000 6 3469 73
24. Teraski S Kanedo S Kobayashi K et al. Histologic features predicting malignant transformation of non-malignant hepatocellular nodules: A prospective study Gastroenterology 1998 115 1216 22
25. Kobayashi M Ikeda K Hosaka T et al. Dysplastic nodule frequently develops hepatocellular carcinoma in patients with chronic viral hepatitis and cirrhosis Hepatology 2004 40 suppl 1 146 abstract
26. Hytiroglou P Theise ND Schwartz M et al. Macroregenerative nodules in a series of adult cirrhotic liver explants: Issues of classification and nomenclature Hepatology 1995 21 703 8
27. Schwartz M Liver transplantation for hepatocellular carcinoma Gastroenterology 2004 127 S268 76