Clinical operational tolerance after kidney transplantation

American Journal of Transplantation

Volumn 6, Issue 4, 2006, Pages 736-746

  Roussey Kesler, G ^a   Giral, M ^a   Moreau, A ^a   Subra, J F ^b   Legendre, C ^c   Noel C ^d   Pillebout, E ^e   Brouard, S ^a   Soulillou, J P ^a  

^a HÔTEL DIEU   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d LILLE UNIVERSITY HOSPITAL   (France)

^e SAINT LOUIS HOSPITAL   (France)

Author keywords

Immunosuppression withdrawal; Kidney transplantation; Operational tolerance

Indexed keywords

ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCINEURIN INHIBITOR; CORTICOSTEROID; CREATININE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HLA ANTIBODY; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2 RECEPTOR ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PROTEIN; STEROID; THYMOCYTE ANTIBODY; VALACICLOVIR; CYCLOSPORIN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; MYCOPHENOLATE MOFETIL; OKT 3;

ABSCESS; ADULT; AGED; ANTIBODY RESPONSE; ARTICLE; BACTERIAL ARTHRITIS; BACTERIAL INFECTION; BASAL CELL CARCINOMA; BLOOD TRANSFUSION; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COLITIS; CREATININE BLOOD LEVEL; EAR NOSE THROAT DISEASE; EPSTEIN BARR VIRUS; FIBROSING ALVEOLITIS; GRAFT RECIPIENT; GRAFT SURVIVAL; GROUPS BY AGE; HEPATITIS C; HERPES; HERPES ZOSTER; HISTOLOGY; HISTORY OF MEDICINE; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; INFECTIOUS DIARRHEA; KIDNEY DONOR; KIDNEY FUNCTION; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; KIDNEY TUBULE DISORDER; LUNG DISEASE; LUNG INFECTION; LYMPHOCYTIC INFILTRATION; LYMPHOPROLIFERATIVE DISEASE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEINURIA; QUALITY CONTROL; RECURRENT DISEASE; SINUSITIS; SKIN CARCINOGENESIS; TREATMENT REFUSAL; TREATMENT WITHDRAWAL; TUMOR; URINARY TRACT INFECTION; VERRUCA VULGARIS; VIRUS INFECTION; ACUTE GRAFT REJECTION; ADOLESCENT; AGE; ALLOGRAFT GLOMERULOPATHY; BACTERIAL SINUSITIS; CHRONIC ALLOGRAFT NEPHROPATHY; CHRONIC GRAFT REJECTION; CORTICOSTEROID THERAPY; DRUG WITHDRAWAL; EPSTEIN BARR VIRUS INFECTION; FEMALE; GLOMERULOSCLEROSIS; GRAFT INFECTION; HEAD AND NECK INFECTION; HISTOPATHOLOGY; HUMAN TISSUE; MAINTENANCE THERAPY; MALE; MEDICAL HISTORY; MIDDLE AGED; OPERATIONAL TOLERANCE; ORGAN DONOR; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE; RENAL GRAFT DYSFUNCTION; TRANSPLANTATION TOLERANCE; TREATMENT RESPONSE; YOUNG ADULT;

EID: 33644771449     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01280.x     Document Type: Article

References (47)

1. Rostaing L Cantarovich D Mourad G et al. Corticosteroid-free immunosuppression with tacrolimus, mycophenolate mofetil, and daclizumab induction in renal transplantation Transplantation 2005 79 807 814
2. Hariharan S Johnson CP Bresnahan BA Taranto SE McIntosh MJ Stablein D Improved graft survival after renal transplantation in the United States, 1988 to 1996 N Engl J Med 2000 342 605 612
3. Soulillou JP Giral M Controlling the incidence of infection and malignancy by modifying immunosuppression Transplantation 2001 72 12 Suppl S89 93
4. London NJ Farmery SM Will EJ Davison AM Lodge JP Risk of neoplasia in renal transplant patients Lancet 1995 346 403 406
5. Dantal J Hourmant M Cantarovich D et al. Effect of long-term immunosuppression in kidney-graft recipients on cancer incidence: Randomised comparison of two cyclosporin regimens Lancet 1998 351 623 628
6. Halloran PF Immunosuppressive drugs for kidney transplantation N Engl J Med 2004 351 2715 2729
7. Nankivell BJ Borrows RJ Fung CL O'Connell PJ Chapman JR Allen RD Calcineurin inhibitor nephrotoxicity: Longitudinal assessment by protocol histology Transplantation 2004 78 557 565
8. Pascual M Theruvath T Kawai T Tolkoff-Rubin N Cosimi AB Strategies to improve long-term outcomes after renal transplantation N Engl J Med 2002 346 580 590
9. Nankivell BJ Borrows RJ Fung CL O'Connell PJ Allen RD Chapman JR The natural history of chronic allograft nephropathy N Engl J Med 2003 349 2326 2333
10. Devlin J Doherty D Thomson L et al. Defining the outcome of immunosuppression withdrawal after liver transplantation Hepatology 1998 27 926 933
11. Takatsuki M Uemoto S Inomata Y et al. Weaning of immunosuppression in living donor liver transplant recipients Transplantation 2001 72 449 454
12. Owens ML Maxwell JG Goodnight J Wolcott MW Discontinuance of immunosuppression in renal transplant patients Arch Surg 1975 110 1450 1451
13. Uehling DT Hussey JL Weinstein AB Wank R Bach FH Cessation of immunosuppression after renal transplantation Surgery 1976 79 278 282
14. Zoller KM Cho SI Cohen JJ Harrington JT Cessation of immunosuppressive therapy after successful transplantation: A national survey Kidney Int 1980 18 110 114
15. Starzl TE Murase N Demetris AJ et al. Lessons of organ-induced tolerance learned from historical clinical experience Transplantation 2004 77 926 929
16. Burlingham WJ Grailer AP Fechner JH Jr. et al. Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient Transplantation 1995 59 1147 1155
17. Christensen LL Grunnet N Rudiger N Moller B Birkeland SA Indications of immunological tolerance in kidney transplantation Tissue Antigens 1998 51 637 644
18. Fischer T Schobel H Barenbrock M Specific immune tolerance during pregnancy after renal transplantation Eur J Obstet Gynecol Reprod Biol 1996 70 217 219
19. Strober S Benike C Krishnaswamy S Engleman EG Grumet FC Clinical transplantation tolerance twelve years after prospective withdrawal of immunosuppressive drugs: Studies of chimerism and anti-donor reactivity Transplantation 2000 69 1549 1554
20. VanBuskirk AM Burlingham WJ Jankowska-Gan E et al. Human allograft acceptance is associated with immune regulation J Clin Invest 2000 106 145 155
21. Brouard S Dupont A Giral M et al. Operationally tolerant and minimally immunosuppressed kidney recipients display strongly altered blood T-cell clonal regulation Am J Transplant 2005 5 330 340
22. Calne RY Prope tolerance: The future of organ transplantation - from the laboratory to the clinic Transplantation 2004 77 930 932
23. Cortesini R Suciu-Foca N The concept of "partial" clinical tolerance Transpl Immunol 2004 13 101 104
24. Starzl TE Murase N Abu-Elmagd K et al. Tolerogenic immunosuppression for organ transplantation Lancet 2003 361 1502 1510
25. Butler JA Peveler RC Roderick P Horne R Mason JC Measuring compliance with drug regimens after renal transplantation: Comparison of self-report and clinician rating with electronic monitoring Transplantation 2004 77 786 789
26. Greenstein S Siegal B Compliance and noncompliance in patients with a functioning renal transplant: A multicenter study Transplantation 1998 66 1718 1726
27. Siegal BR Greenstein SM Postrenal transplant compliance from the perspective of African-Americans, Hispanic-Americans, and Anglo-Americans Adv Ren Replace Ther 1997 4 46 54
28. Chisholm MA Vollenweider LJ Mulloy LL et al. Renal transplant patient compliance with free immunosuppressive medications Transplantation 2000 70 1240 1244
29. Vlaminck H Maes B Evers G et al. Prospective study on late consequences of subclinical non-compliance with immunosuppressive therapy in renal transplant patients Am J Transplant 2004 4 1509 1513
30. Carter JT Lee CM Weinstein RJ Lu AD Dafoe DC Alfrey EJ Evaluation of the older cadaveric kidney donor: The impact of donor hypertension and creatinine clearance on graft performance and survival Transplantation 2000 70 765 771
31. Rao KV Kasiske BL Odlund MD Ney AL Andersen RC Influence of cadaver donor age on posttransplant renal function and graft outcome Transplantation 1990 49 91 95
32. Terasaki PI Gjertson DW Cecka JM Takemoto S Cho YW Significance of the donor age effect on kidney transplants Clin Transplant 1997 11 5 Pt 1 366 372
33. Roels L Waer M Coosemans W Christiaens MR Vanrenterghem Y The influence of donor age on initial and long-term renal allograft outcome. Leuven Collaborative Group for Transplantation Transpl Int 1994 7 Suppl 1 S303 305
34. Koning OH Ploeg RJ van Bockel JH et al. Risk factors for delayed graft function in cadaveric kidney transplantation: A prospective study of renal function and graft survival after preservation with University of Wisconsin solution in multi-organ donors. European Multicenter Study Group Transplantation 1997 63 1620 1628
35. Roussey-Kesler G Ballet C Aubin JT et al. Humoral and cellular response to influenza vaccination in human recipients naturally tolerant to a kidney allograft (Abstract) Basic Science Symposium La Baule France 2005
36. Opelz G Terasaki PI Dominant effect of transfusions on kidney graft survival Transplantation 1980 29 153 158
37. Soulillou JP Bignon JD Peyrat MA Guimbretiere J Guenel J Systematic transfusion in hemodialyzed patients awaiting grafts: Kinetics of anti-t and b lymphocyte immunization and its incidence on graft function Transplantation 1980 30 285 289
38. Fehrman I Ringden O Moller E Blood transfusions as pretreatment for kidney transplantation: Immunization rate and effect on cellular immune response in vitro Transplantation 1983 35 339 343
39. Terasaki PI Ozawa M Predicting kidney graft failure by HLA antibodies: A prospective trial Am J Transplant 2004 4 438 443
40. Hourmant M Cesbron-Gautier A Terasaki PI et al. Frequency and clinical implications of the development of donor-specific and non donor-specific HLA antibodies after kidney transplantation J. Am. Soc. Nephrol 2005 in press
41. Fehr T Sykes M Tolerance induction in clinical transplantation Transpl Immunol 2004 13 117 130
42. Salama AD Najafian N Clarkson MR Harmon WE Sayegh MH Regulatory CD25+ T cells in human kidney transplant recipients J Am Soc Nephrol 2003 14 1643 1651
43. Baeten D Louis S Braud C et al. Phenotypically and functionally distinct CD8+ lymphocyte populations in long term drug-free tolerance and chronic rejection in human kidney graft recipients J. Am. Soc. Nephrol. 2005 in press
44. Schwarz A Gwinner W Hiss M Radermacher J Mengel M Haller H Safety and adequacy of renal transplant protocol biopsies Am J Transplant 2005 8 1992
45. Li Y Koshiba T Yoshizawa A et al. Analyses of peripheral blood mononuclear cells in operational tolerance after pediatric living donor liver transplantation Am J Transplant 2004 4 2118 2125
46. Derks RA Burlingham WJ In vitro parameters of donor-antigen-specific tolerance Curr Opin Immunol. 2005 17 560
47. McLaughlin K Wu C Fick G Muirhead N Hollomby D Jevnikar A Cytomegalovirus seromismatching increases the risk of acute renal allograft rejection Transplantation. 2002 74 813 816